Herpes 6 types: symptoms and treatment in children and adults
The word "herpes" in most people is associated with unpleasant blistering rashes in the area of the lips or genitals.Indeed, these symptoms are a manifestation of a herpetic infection caused by herpes simplex virus type 1 or type 2.However, the clinical manifestations of herpetic infection do not end there, because there are 8 types of herpesviruses, and all of them are capable of provoking the development of certain pathological conditions.This article will be devoted to a fairly "young", opened in 1986, a representative of the herpesvirus family - the herpes simplex virus type 6 and related diseases.Table of contents: Features of the herpes simplex virus type 6 Diseases related to HHV-6 Herpes type 6 in children Herpes type 6 in adults Diagnosis Herpes 6 types: treatment
Features of the herpes virus type 6Recommended to read:
VirusHerpes simplex type 6( HHV-6) is generally similar to the rest of herpesviruses, but has a number of characteristics( "likes" to kill lymphocytes, is insensitive to antiviral drugs that are commonly used for herpes infection, etc.).
There are two types of HHV-6 : the first( A) - neurotropic virus( presumably plays a role in the development of multiple sclerosis), the second( B) - provokes the occurrence of roseola, lymphoproliferative and immunosuppressive diseases.
Infection with HHV-6 occurs predominantly by airborne injection of , although vertical transmission( from mother to child) and parenteral( for example, with blood transfusion, organ transplantation) routes of transmission of this infection are not ruled out.
Diseases associated with HHV-6
Herpes 6 types of symptoms has a fairly polymorphic.Primary infection people, as a rule, are transferred in the form of sudden exanthema( roseola) even in childhood. In addition, ingestion of the herpesvirus type 6 virus can trigger the emergence of a number of other pathological conditions( the relationship between many of them and HHV-6 still remains at the hypothesis level and requires further study and confirmation):
- Syndrome of chronic fatigue.
- Febrile seizures.
- Infectious mononucleosis, not associated with infection with the Epstein-Barr virus.
- Diseases of the central nervous system( multiple sclerosis, encephalitis, meningitis, etc.).
- Necrotizing lymphadenitis( inflammation of lymph nodes accompanied by enlargement and necrotic destruction).
In the future, the persistence of the virus in the human body is almost not manifested. In rare cases, the associated pathological infections associated with persistent HHV-6 are possible:
- Lymphoproliferative diseases( manifested by enlarged lymph nodes and immunodeficient conditions).
- Malignant lymphomas( eg, non-Hodgkin's lymphoma).
In addition, in a number of studies, scientists have received data on the possible association of infection of women with HHV-6 and the development of complications of pregnancy leading to fetal death of the child or premature birth.
It should also be noted that the herpesvirus type 6 is a co-factor( accelerator of the onset and development of the disease) of AIDS, cervical cancer and carcinoma of the ENT organs.
Herpes 6th type in children
For 6 months, children are usually protected from HHV by their mother's antibodies, so they do not suffer from roseola.Subsequently, due to the high susceptibility of the child's organism, any contact with this virus ends with infection, but sudden exanthema does not develop in all children.
The main manifestations of HHV-6 infection in childhood:
- Increased body temperature( fever lasts no more than 3 days).
- Nasal congestion, slightly reddened throat.
- A patchy skin rash that occurs after the normalization of body temperature and disappears very quickly without any medical intervention, leaving no trace.
- In rare cases, babies develop febrile seizures.
In general, type 6 herpes in children is not something terrible and dangerous .Sooner or later, almost all the guys are facing this virus.And many parents do not even know that their child has recovered with roseola, because the clinical picture of this disease is very similar to the usual ARVI, and the rash on the skin is written off for an allergic reaction associated with taking antipyretics or other medications.
Type 6 herpes in adults
Almost all adults face HHV-6 when they are young, so they do not get a roseola, but the reactivation of the virus in the body under the influence of a number of provoking factors can cause the development of certain diseases.The factors that cause the activation of the infectious process include stress, a strong emotional and intellectual overwork, acute viral diseases and chronic illnesses( they suppress immunity). Reactivation of HHV-6 can cause the development of the syndrome of chronic fatigue, multiple sclerosis and other serious CNS lesions in adults.
For civilized countries, due to the prevalence of mental loads over physical labor among the population, the chronic fatigue syndrome is a particularly urgent problem. It is possible to suspect its development on the basis of the following symptoms:
- Unexplained fatigue, which does not go away even after a long rest.
- Apathy to everything and everyone
- Increased aggressiveness and bouts of anger.
Multiple sclerosis is another disease that physicians tend to associate with infection with HHV-6.The main mechanism of development of this pathology is in autoimmune reactions, due to which the myelin sheath of nerve fibers in the central nervous system is damaged.Because of this, the connection between nerve cells is lost.The disease manifests a variety of neurological symptoms( their nature is determined by which part of the central nervous system is most affected).
There are several methods for diagnosing HHV-6 infection:
- Immunoenzymatic analysis( the specific antibody titer is determined).
- Detection of virus DNA in blood or other biological fluids and tissues by polymerase chain reaction( PCR).
Diagnosis of the presence of HHV-6 in the body is not available to all patients with the symptoms of this infection.The need for it arises in disputable cases, when doctors need to decide on the choice of an antiviral drug when the patient is in serious condition and it is vital to identify the cause of the disease( for example, with meningitis, encephalitis), when physicians can not find the cause of the increase in lymph nodes and immunodeficiency conditionsetc.To survey the same infection of a child with symptoms of roseola is inadvisable, because until the results of analysis the patient can fully recover.
Herpes 6 types: treatment
Several groups of medicines are used to treat HHV-6 infection:
- Antiviral drugs.With a certain success, various drugs( acyclovir, ganciclovir) are used, but not effective enough for HHV-6 and safe for the patient's health.
- Immunoglobulins( specific antibodies).
These drugs are used only for severe, life-threatening diseases, for example, neuroinfections, multiple organ dysfunction, immunodeficiency states, etc. In case of roseola, the most frequent manifestation of HHV-6 infection, no specific antiviral treatment is performed, therapists are limited to only symptomatic therapy.
Zubkova Olga Sergeevna, medical reviewer, epidemiologist