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Analysis on CEA( analysis for cancer-embryonic antigen)

Analysis on CEA( analysis for cancer-embryonic antigen)

Under the abbreviation REA is meant a specific cancer-embryonic antigen.This protein compound is synthesized by the epithelial cells of the child's gastrointestinal tract during the period of intrauterine development.

Table of contents: Where is CEA contained?Explanation of the analysis for cancer-embryonic antigen Cancer-embryonic antigen: norms Pathology, in which the assay is prescribed for CEA

Where is the CEA contained?

The minimum presence of this oncofetal protein is determined in scanty amounts in the epithelium of the bronchi and the digestive tract.

In adult patients, this compound is synthesized in extremely small volumes by the epithelium of the mammary glands, the digestive tract and the respiratory system( bronchial tubes).The protein is practically absent even in the blood of a pregnant woman.

Interpretation of the assay for the cancer embryonic antigen

If laboratory studies show that there is an increase in the level of this oncofetal antigen in the dynamics, this often indicates the development of a malignant tumor.

In 70% of cases the level of CEA is elevated with the following non-oncological pathologies:

  • Rakovo-embrionalynyj-antigen11 chronic pancreatitis;
  • Chronic decreased functional activity of the kidneys;
  • chronic inflammation of the pancreas;
  • chronic hepatitis;
  • Crohn's disease;
  • polyps of large intestine;
  • ulcerative colitis;
  • pneumonia;
  • chronic bronchitis;
  • Cystic fibrosis;
  • is a tuberculosis lesion;
  • series of autoimmune pathologies.

Important: with the same frequency, this specific antigen is detected in nicotine dependence and in people suffering from chronic alcoholism.


The level of cancer embryonic antigen is increased in 100% of patients suffering from malignant lesions of the large intestine.

With a probability of 90%, the presence of this cancer marker indicates cancerous tumors of the following organs:

  • stomach;
  • rectum;
  • easy;
  • ovaries;
  • mammary glands;
  • pancreas.

CEA in 90% of cases indicates the formation of secondary tumor lesions( metastasis) in liver tissue and bones.

In malignant tumors localized in the head and neck region, this protein antigen is detected in 70% of diagnosed cases.

Cancer-embryonic antigen:

Important: , the reference values ​​for antigen content in the blood do not exceed 5 ng / ml.A slight increase in normal indicators is typical for people with tobacco and( or) alcohol dependence.

Up to 7-10 ng / mL, the indicator may increase with the following pathologies:

  • pneumonia;
  • pulmonary tuberculosis;
  • bronchitis( acute or chronic);
  • cirrhosis of the liver;
  • chronic hepatitis;
  • inflammation of the pancreas;
  • Crohn's disease;
  • colitis( ulcerative).

Pathologies in which a specialist prescribes analyzes for the oncofetal antigen

The physician assigns an assay for CEA to patients suffering from the following diseases:

  • miliary, focal and infiltrative pulmonary tuberculosis;
  • severe liver damage( hepatitis and cirrhosis);
  • chronic renal failure;
  • ulcerative inflammation of the large intestine;
  • granulomatous enteritis( Crohn's disease);
  • chronic pancreatitis;
  • pneumonia;
  • Cystic fibrosis.

Important: is mandatory for the patient to be screened for suspected malignant tumors of the stomach, lung, colon and prostate.

Plisov Vladimir, medical reviewer

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