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Mezim: brief instructions and analogues

Mezim Mezim - a drug belonging to the category of enzymatic, is used in the treatment of diseases of the organs of the gastrointestinal tract and to improve the digestive processes.Mezim is released in pharmacies without prescriptions and many people take it without any prescription of the doctor - in principle, this option is acceptable, but still need to read the official instruction to exclude contraindications and prevent overdose.

Contents: What does Mezim consist and how does it work? Indications for using Mezima How to take Mezim Possible side effects Analogues of Mezim

What does and how does Mezim work

The main active substance of the drug in question is pancreatin , the active componentsAre considered lipase, amylase and protease.Excipients, that is, excipients, which in no way affect the clinical picture, are aerosil, carboxymethyl starch, magnesium stearate.

Mezim is a tablet coated with a dispersion of polyacrylate, talc, titanium dioxide, hypromellose, macrogol, simethicone emulsion, azorubin varnish.

With the use of the drug in question, all of its main active substances begin to "work" only in the duodenum, although before that they are mixed with food in the stomach. Enzymes that enter the body are not only able to improve / make digestion complete, but also increase the secretion of the secretion of the pancreas.

Indications for the use of Mezima

The official regulations for the enzyme preparation in question indicate the following conditions in which its administration is advisable:

  • inflammatory or dystrophic changes in the tissues of organs involved in the digestive process;
  • indigestion, loose stools, bloating if they are associated with previous surgical intervention on the organs of the gastrointestinal tract;
  • decreased activity of the secretory function of the pancreas;
  • preparation for a routine abdominal examination using ultrasound or X-ray.

In addition, Mezim can act as an "ambulance" in case of overeating, a sharp change in the diet table for a general, eating a lot of fatty foods or incompatible products.


Note: , although Mezim is considered a safe drug and can be used in certain conditions without prescribing a doctor, it is worth knowing and contraindications to this - pancreatitis, which occurs in acute form or in the period of exacerbation of its chronic course,Sensitivity to components.

Separately, it is worthwhile to clarify the use of Mezima by pregnant women and during breastfeeding.Some studies in this direction were conducted, but they remained unfinished, therefore it is impossible to establish exactly how the active substances of the drug in question affect the fetal development of the fetus and the infant's health.In this regard, doctors do not recommend the use of Mezima during pregnancy and lactation.

How to take Mezim

How to take mezim The considered medicinal product of the enzymatic category should be taken orally before or during meals.Swallow tablets need to be whole, because when chewing them, the protective shell is damaged, and all the active components of Mezim are neutralized under the influence of gastric juice - the result will be a complete loss of pharmacological capabilities.

If Mezim is taken with a medical purpose, the dosage and duration of the appointment is determined by the attending physician - this will depend not only on the specific diagnosis, but also on the severity of the pathology, the overall health of the patient.

The official instructions of Mezima indicate general recommendations - adults should consume 1-2 tablets immediately before meals three times a day .If the doctor determines the need to additionally take 1-2 tablets during meals, then this is also acceptable.

The duration of administration of the medicinal product in question can not be specified accurately, it is of a variable nature.For example, if Mezim is used in the case of banal overeating, then this method will have a one-off character.But during the course of therapy the duration of treatment can be 2-3 months.

Possible side effects of

As a rule, Mezima is not accompanied with side effects even for a long time, but in some cases there may be unpleasant sensations / pain in the anatomy of the stomach( epigastric abdomen), nausea, allergic reaction in the form of rashes andItching of the skin, constipation or diarrhea.

If the considered drug of the enzymatic group is taken by the patient for a long time, it can provoke an increase in the concentration of uric acid and an increase in its quantity in the blood.Therefore, when appointing a long therapeutic course Mezim, the doctor should periodically refer the patient to a laboratory blood test.

Note: if Mezim is taken by patients with cystic fibrosis, some areas of the intestine may narrow, but this side effect is extremely rare and is an exception.

Overdose Mezimom is rare, but if it does, constipation, severe nausea, and intense pain in the epigastric abdomen can develop.Such symptoms are a reason for drug withdrawal and symptomatic therapy.

Analogues of Mezima


The pharmacological industry also produces analogues of this drug that will be similar to it in its action and composition.


An enzymatic preparation that has a rather wide range of uses:

  • insufficiency of secretion of pancreatic secretion, no matter what exactly this condition is caused by;
  • Cystic fibrosis is a disease of a hereditary etiology that is characterized by obstruction / obstruction of the pancreatic ducts;
  • inflammatory or dystrophic pathological processes in the liver, stomach or gallbladder;
  • chronic meteorism( accumulation of gases in the intestine);
  • recovery period after surgical removal of part of the stomach, pancreas, gallbladder or intestine;
  • violation of the patency of the ducts of the gallbladder and pancreas( obstructive conditions).

Pancreatin is often prescribed to people who are forced to occupy a reclining position for a long time, who has a malfunctioning function.The analogue of Mezim under consideration is included in the preparatory complex of measures before the passage of planned ultrasound or roentgenological examination of the abdominal cavity organs.

Side effects in Pancreatin are few and they most often manifest only with prolonged use of the drug - these can be disorders of the intestine, unceasing nausea, narrowing of the intestinal lumen .A distinctive feature of this analogue from Mezim is a high probability of developing an allergic reaction.


Perhaps the best-known enzyme preparation, which is actively used for fast and forced digestion of proteins, carbohydrates and fats in the digestive tract. Its composition and pharmacological action are identical to Mezim, among the indications for use it is possible to distinguish:

  • accumulation of a large number of gases in the intestines, the cause of which was cholecystitis;
  • obligatory bowel cleansing before the planned roentgenogram;
  • derangement of stools due to prolonged use of antibacterial agents;
  • problems with digestibility of elements and digestion in general in elderly and senile people.

Naturally, Festal is indicated in case of insufficient formation and release of enzymes by the pancreas, which can be associated with various pathologies of the gastrointestinal tract.

The considered Mezim analogue is taken in the amount of 1-2 tablets during or after meals three times a day.Contraindications to the use of Festal are blockage of the bile ducts and inflammatory processes in the liver tissues.

Mezim and its analogs are effective enzyme preparations that are completely permitted to be taken on their own when overeating, eating too much fatty foods or incompatible products.But this does not mean that you can ignore the instructions in the official instructions - you need to take into account both contraindications to use, and special instructions regarding dosages.

Tsygankova Yana Aleksandrovna, medical reviewer, therapist of the highest qualification category

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