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Efferalgan: instructions for use, release forms, analogs

Efferalgan

Efferalgan is an effective analgesic antipyretic which is recommended for symptomatic treatment of colds, ARVI and pain syndrome of various genesis and localization.The drug is available in the form of dispersible tablets, syrup( for children) and rectal suppositories.

Table of contents: Active substance and dosage forms Indications Who is Efferaulgan contraindicated?Recommended dosages and administration scheme Side effects Pharmacological action Application in pregnancy and lactation Interaction with other drugs Overdose Storage and dispensing conditions from pharmacies Analogs of Effergangan

Active substance and dosage forms

Efferalgan Active component of Effergangan is a non-steroidal anti-inflammatory drug paracetamol.

Each effervescent tablet contains 500 mg of paracetamol, and in suppositories - 80, 150 or 300 mg.

For children aged 1 month.(With a body weight ≥ 4 kg), yellow-brown syrup is sold in pharmacies with a pleasant vanilla scent.In 100 ml contains 3 g of paracetamol.

Important: the parents of a child with diabetes should remember that syrup contains sucrose.

Tablets are supplied in blisters( 4 pcs.), Candles - in contour packs( 5 pcs.), And syrup - in polymer bottles( 90 ml).A convenient measuring spoon is supplied with the child's Effergangan.

Indications

Efferalgan is recommended for treatment of febrile syndrome in infectious and inflammatory diseases.

The drug is also recommended for:

  • myalgia;
  • arthralgia;
  • toothache;
  • painful menstruation;
  • post-traumatic pain syndrome.

Note: Efferlangan syrup is good for babies from pain during teething and helps to bring down the temperature when the body reacts to the introduction of vaccines.

Who is contraindicated Efferlangan?

This drug should not be taken to patients with individual hypersensitivity to paracetamol to avoid the development of severe allergic reactions.

Contraindications include:

  • marked functional liver failure;
  • closed angle glaucoma;
  • "aspirin triad"( bronchial asthma in combination with nasal polyposis and intolerance to salicylates);
  • severe renal failure.

Important: should be especially careful for people with alcohol dependence, as well as for elderly patients.

Those who adhere to diets with restriction of table salt, we must remember that in the dispersible tablets are present over 400 mg of sodium.

effervescent tablets Efferlangan are not given to children under 2 years of age or weighing less than 13 kg .

Recommended dosages and dosage regimen

Efferalgan Dispersible tablets are pre-dissolved in 150 ml of boiled water.For adolescents from 15 years and adult patients, a single dose is 1-2 tablets of ( depending on the severity of the symptoms), and the frequency of application is up to 4 times a day.Between the methods it is strongly recommended to withstand the time intervals of 4-6 hours to avoid the development of a hepatotoxic effect.

Important: for children is given in terms of 10-15 mg of paracetamol per kg of body weight per day.The daily dosage should not exceed 60 mg / kg.

Babies from 2 to 7 years of age are given ½ tab.With an interval of 6 hours( not more than 2 pieces per day).

For children from 7 to 10 years effective safe dosage = ½ tab.Effergangan;The interval should be 4 hours( up to 3 pieces per day).

Patients aged 10 to 15 years can take 1 tablet.Not more than 4 times a day.

The duration of symptomatic therapy should not exceed 3 days .If necessary, continue treatment should consult a district therapist.Continuous use of paracetamol requires monitoring of the pattern of peripheral blood and the functional activity of the liver.

Side effects of

Most patients very well tolerate symptomatic therapy with Effergangan.With allergy to paracetamol, it is possible to develop skin itch and rash, as well as angioedema.In severe cases, anaphylactic shock is not excluded.

In rare cases, the following side effects are noted:

  • fall in blood pressure( arterial hypotension);
  • fatigue;
  • dizziness;
  • dyspeptic disorders.

Important: in laboratory testing of peripheral blood against the background of abuse Efferalganom may be noted anemia, leukopenia and thrombocytopenia( reduction in the number of shaped elements).

Pharmacological action

Efferalgan Paracetamol is a non-selective inhibitor of the cyclooxygenase enzyme.Suppression of its activity leads to a decrease in the synthesis of mediators of pain - prostaglandins and slowing of the nerve impulse

Thanks to the direct effect on the hypothalamic center of thermoregulation, paracetamol allows you to fight hyperthermia against colds and ARVI.

After taking Efferalgan solution, the active substance is quickly and completely absorbed in the gastrointestinal tract.Already after 20 minutes, there is a decrease in the temperature and intensity of the pain syndrome.The highest level of paracetamol in the serum is fixed in half an hour-hour.The process of biotransformation of NSAIDs takes place in the liver, and the substance and its inactive products of metabolism through the intestine are excreted.Half-life is about 2 hours on average.

Application in pregnancy and lactation

Paracetamol does not have teratogenic or embryotoxic effects, however, Efferlangan during gestation and breastfeeding of the baby is not recommended for .If there is a need for symptomatic treatment during lactation, it is advisable to temporarily transfer the child to artificial feeding.

Interaction with other medicines

Paracetamol potentiates the effect of indirect anticoagulants and antiplatelet agents, therefore, when these drugs are used in parallel, the risk of bleeding of various locations increases.

Simultaneous reception of barbiturates reduces the antipyretic effect of Effergangan.

Severe poisoning, even with a slight excess of tolerable dosages, may develop if the patient receives tricyclic antidepressants, phenytoin or an antibacterial agent Rifampicin.

During treatment, it is highly undesirable to take other NSAIDs, because the risk of toxic effects on the kidneys increases.

The likelihood of developing glaucoma increases when taking Efferalgan against hormonal therapy with glucocorticosteroids.

Overdose

Paracetamol poisoning is possible in adults when taking ≥ 10 g of this substance.

With a significant excess of single and daily doses, the following symptoms develop:

  • decrease or total absence of appetite;
  • feeling tired;
  • abdominal pain;
  • dyspepsia disorder;
  • is an intestinal disorder.

Taking high doses can cause severe liver damage( including hepatonecrosis - necrosis of tissues), which is accompanied by progressive encephalopathy.

Complications such as metabolic acidosis and coma are not excluded.In severe cases, an overdose leads to the death of the victim.

In case of an overdose, call an ambulance.In the first 2 hours after an overdose, the patient should be washed with a stomach and given enterosorbents( activated charcoal). Within 8-9 hours, it is necessary to introduce a specific antidote - methionine, and if more than 12 hours pass, detoxification requires the introduction of acetylcysteine.The victim needs hospitalization.He is often shown the hardware purification of blood - hemodialysis.

Storage and dispensing conditions from pharmacies

You do not need a doctor's prescription to purchase Effergangan in pharmacy chains.

The medicine should be stored in places with a low level of humidity, at temperatures ranging from +15 to +30 ° C.

Shelf life is 3 years from the date of issue( it is indicated on the packaging).

Keep out of the reach of children!

Analogs of Effergangan

The Effergangan analogues of the active substance are:

  • Paracetamol MS;
  • Antigrippin;
  • Acetaminophen;
  • Aldolor;
  • Kalpol;
  • Panadol;
  • Tylenol;
  • Rapidol;
  • Ithymol;
  • Meksalen;
  • Grippostad;
  • Cefexon D;
  • Fabricet.

Plisov Vladimir, medical reviewer


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