Drugs used to treat dermatomycosis in humans
Jul 07, 2018
Dermatomycosis in medicine is called a vast group of infectious skin lesions, the appearance of which is provoked by various types of pathogenic fungi-dermatophytes.Similar lesions can be observed in adults and children, but in any case, you need to see a doctor and conduct a full treatment.Of course, there are many folk methods for treating dermatomycosis, and often they are effective.But the "secret" is that the effect of relief in the treatment of dermatomycosis has a short-term character, then all the symptoms of the disease "flare up" with greater intensity.That's why doctors insist on conducting competent drug treatment.Table of contents:
Antifungal systemic remedies for the treatment of dermatomycosis
Since antifungal agents have toxic effects, they can not be taken in an independent regimen and even more without the expert's advice to adjust the dosage of .Below are presented preparations in the tablet form, taken with dermatomycosis.
Analogues - Itrazole, Rumikoz, Canditral, Irunin
This is a synthetic antifungal agent that has a wide spectrum of action against dermatophytes.Take this drug should be at least 2-4 weeks and only after that it will be possible to evaluate the effectiveness of treatment.
Itraconazole has contraindications to the use of :
- period of pregnancy and lactation;
- kidney failure;
- lung diseases that occur in severe form;
- ischemic heart disease;
- hearing impairment;
- hepatic impairment.
Extremely cautious this antifungal drug is prescribed for children and the elderly.
Why do doctors categorically not recommend taking itraconazole uncontrollably? The fact is that this drug has many side effects:
- diarrhea and / or constipation;
- leukopenia / neutropenia / thrombocytopenia;
- decreased visual acuity;
- peripheral neuropathy;
- violation of taste perception;
- acute hepatic impairment.
And this is only part of the possible side effects!Often, patients who take this medication complain about rashes, itching and burning in certain places of the body, problems with sexual desire.Women may experience menstrual irregularities and urinary incontinence.
Analogues - Mikoflukan, Mikomaks, Flukostat
This antifungal agent is highly specific because it inhibits the activity of pathogens of dermatomycoses, disrupts their growth and spread.
- pregnancy and lactation period;
- simultaneous reception of Terfenadine and Astemizole.
Extremely cautious this antifungal drug should be taken to people with organic heart disease and liver failure.
Fluconazole( and its analogs) can also have side effects that cause disruption in almost all body systems:
- digestive system - changes in taste, flatulence, nausea, diarrhea or constipation, functional liver disorders;
- Nervous system - frequent dizziness, convulsions, spontaneous headache;
- hematopoiesis system - thrombocytopenia, leukopenia, neutropenia;
- cardiovascular system - a flutter of the ventricles.
In addition, taking the antifungal drug in question can cause allergic reactions - urticaria, face swelling, intense skin itching, exudative erythema, angina neurotic shock.
Fluconazole and its analogs belong to the azole group of medicines, when taken, they should be consumed with a sufficient amount of water, and they should be consumed directly during meals.If a patient with dermatomycosis has a low gastric acidity, Fluconazole tablets should be taken with a liquid that has an acidic reaction. When taking any drug from the group of azoles, including Fluconazole, it is strictly forbidden to use Pimozide, Quinidine, Astemizole, Simvastatin.
Analogues - Terbinox, Terbisil, Braamisil, Lamisil
This drug belongs to the group of allylamines, it has a wide range of effects on mushrooms dermatophytes, which are one of the causative agents of dermatomycosis.Terbinafine has quite a few contraindications - it is not recommended for patients who are diagnosed with chronic liver and kidney diseases with frequent relapses, as well as during pregnancy and lactation.
Terbinafine, like all antifungal agents, has a fairly high toxicity, so when it is used, the following side effects may occur:
- nausea, diarrhea and recurrent abdominal pain;
- feeling of constant stomach overflow.
In addition, the antifungal agent under consideration can adversely affect the human immune system, which can trigger the development of systemic or cutaneous lupus erythematosus.Often, patients taking Terbinafine, note the appearance of dermatological reactions - for example, there may appear psoriasis-like rashes on the skin.
Terbinafine is taken orally, with enough water and with no food intake.
This is one of the earliest natural antimycotics that has a narrow spectrum of activity, therefore it is used only for the treatment of dermatomycosis caused by fungi-dermatomycetes.Griseofulvin is used to treat severe dermatomycosis. This drug belongs to the group of antibiotics.
Contraindications to the use of Griseofulvin:
- children under 2 years;
- period of bearing and feeding of the child;
- diagnosed malignant tumors;
- lupus-like syndrome;
- organic liver and kidney pathologies;
- systemic blood diseases.
Occurrence of side effects in the treatment of a given drug is, in principle, a frequent fact. The whole organism suffers from the toxic effect of the drug, therefore the following changes in the functioning of the systems are possible:
- digestive system - nausea and vomiting, diarrhea, hepatitis, candida-associated stomatitis;
- nervous system - dizziness and insomnia, movement coordination disorders and confusion, disorientation and headache;
- hematopoiesis system - granulocytopenia, agranulocytosis, leukopenia.
In addition, there is often an allergy in the treatment of Griseofulvin - urticaria, lupus-like syndrome, exudative erythema, toxic epidermal necrolysis.
This medication should be taken with or immediately after a meal, and if the patient complies with a low-fat diet, each Griseofulvin tablet should be taken with a tablespoon of vegetable oil.
Please note: treatment of dermatomycosis with these antifungal agents is strictly forbidden to combine with the use of alcoholic beverages.You can not start treatment with these drugs without prescribing a doctor, arbitrarily change the dosage or duration of therapy - this is fraught with the development of complications of the disease.
The use of local remedies for the treatment of dermatomycosis
Local remedies in the treatment of dermatomycosis play an important role, because they are able to quickly reduce the level of unpleasant / uncomfortable sensations on the affected skin.In addition, all topical preparations have anti-inflammatory, anti-edematous effects, are able to relieve the patient of itching.
Before using antifungal ointments, creams and sprays, you need to visit a doctor and clarify the diagnosis.It is on the basis of such data that a specialist will be able to appoint competent treatment with an effective drug.
Pimafurcot( cream, ointment)
This is a combined preparation that has antifungal and anti-inflammatory effects.It is effective not only in the treatment of "classical" dermatomycosis, but also in case of attachment to the underlying disease of bacterial infection.
The use of Pimafurcot( cream, ointment) is categorically contraindicated in the presence of open wounds on the skin in places of intended application of the product and in viral infections of the skin.
Use this drug to treat dermatomycosis possible in children from birth, but until the age of 1 year should be careful and apply cream / ointment under the supervision of a doctor.
Afloderm( cream, ointment)
The drug is classified as a non-halogenated synthetic glucocorticoid and is actively used to treat various types of dermatomycosis.There are also Afloderm analogues, but this particular drug can be used in the face and genital area.
It is possible to use this medicinal product of local significance from the age of six months of infants, it is not forbidden to apply Afloderm to affected areas of the skin and lactating women, but it is necessary to avoid getting the drug on the area of the mammary glands.
Acriderm( cream, ointment)
This is a fairly fast drug from the group of glucocorticoids.Its use is strictly forbidden at the age of a child under 6 months and for women who breast-feed a child.Pregnant women, in principle, are allowed to use Acriderm to treat dermatomycosis, but in low doses and short courses.
This is a long-known topical preparation that has the ability to penetrate the skin and accumulate in its stratum corneum.The drug Sinaphlan( ointment) is found in the skin and 15 days after the last moment of its use.
Please note: as this medication penetrates into the blood and exerts a toxic effect on the entire body, it can not be categorically used to treat foci of dermatomycosis on the delicate skin of the face.For the same reason, Sinaphlane is not applied under the bandages.
Ointment or Cream Sinaphlan is permitted for pregnant women, but with caution and not in the first trimester of pregnancy.Women who are in the period of lactation, you can use Sinaflan, but only for a short time and in limited areas of skin.In general, the considered type of medicinal product is used for the treatment of pregnant and lactating women only in exceptional cases, when other methods of treatment do not give a positive effect.
Advantan( emulsion, cream, ointment)
A modern glucocorticoid that is highly effective.Advantan is practically not absorbed into the blood and can be used to treat fungal diseases with lesions on the face and in the external genital area.
Children can be prescribed Advantan from the age of four months, during pregnancy and feeding to women, as a rule, this drug is not prescribed, or its use is under the supervision of a doctor.
It is strictly forbidden to use Advantan in any pharmacological form for viral skin lesions at places of presumed application of the drug.
Important! The scheme of treatment of dermatomycosis is selected by the doctor in strictly individual order.But it necessarily includes immunomodulators, vitamin-mineral complexes and antiseptic solutions.Vitamins and immunomodulators strengthen the immune system of the sick person's body, help it to fight fungal lesions.And antiseptic solutions are used to treat the wetting areas of the skin, boric acid, chlorhexidine can be classified as such.
Treatment of dermatomycosis is a long process, in some cases it is necessary to take specific medications prescribed by a doctor for 3-6 months.The doctor should necessarily observe the course of treatment of dermatomycosis, because at any time a replacement of the drug may be necessary.
Tsygankova Yana Aleksandrovna, medical reviewer, therapist of the highest qualification category