ACS: form of release, pharmacological action, rules of application
Jul 08, 2018
ACS is a medicinal product that belongs to the group of mucolytics, in addition it is insensitive, but it has a beneficial effect on the inflammatory process and congestion in the bronchi.This drug is dispensed in pharmacies without a prescription, but it should still be taken as prescribed by the doctor - the instructions indicate a clear differentiation of prescriptions / dosages, which implies an assessment of the patient's condition and the determination of not only the exact diagnosis but also the stage of the disease course.Table of contents: Composition of the preparation, its pharmacological action and form of use Indications / contraindications for use ATSTS How to take ACCS Possible side effects Drug interaction
Composition of the drug, its pharmacological action and form of release
The main active substance in the drug in questionActs acetylcysteine, which has the ability to exert a pneumoprotective and antioxidant effect.When ACC is taken inside, a disruption of bisulphide bonds in sputum occurs - this explains the ability of the preparation to make mucus accumulated in the upper respiratory tract, less viscous.
Acetylcysteine is absorbed already in the gastrointestinal tract( if taken internally), it was revealed during the studies that the highest level of acetylcysteine concentration is determined after 3 hours, in some cases this period is one hour.The complete withdrawal of the remnants of the drug in question takes place within an hour, but if the patient has liver problems( for example, there is progressive liver failure), the withdrawal time of the drug residues will be 8 hours.
It is produced in two pharmacological forms - tablets( effervescent, for dissolution in water) and powder( for the preparation of either a hot beverage or a cold one).
Indications / contraindications for use ACS
This medication is often used in medical practice - it is prescribed for patients with respiratory system diseases, when a large amount of viscous sputum is accumulated against the background of the pathological process.
Unconditional indications for the treatment of ATSs are:
- acute / chronic bronchitis of various kinds( obstructive part of this category);
- bronchial asthma;
- otitis exudative type of middle ear;
- cystic fibrosis;
- bronchiectatic disease;
The considered drug can be taken only after the coordination of treatment tactics with the doctor - the ACC has a number of categorical contraindications to .You can not take ATSTS in case of diagnosed ulcerative lesions of the gastric mucosa( type of peptic ulcer - peptic), fructose intolerance of congenital / hereditary character( it is a part of the drug as an auxiliary component), an allergic reaction to acetylcysteine.Do not appoint ATSTS for pulmonary bleeding, even if they are spontaneous and non-intensive.
Note: The intake of the drug in question in childhood is quite acceptable, but if the child has hepatitis or renal insufficiency, then ACC is contraindicated, since there is a high probability of accumulation in the body of products with a high nitrogen content, which will lead to a deterioration.
Separately it is necessary to learn about whether it is possible to take ATSTS pregnant and lactating women. Acetylcysteine has no embryotoxic effect, that is, there is no effect on the fetal development of the fetus.But in any case, the decision on the appropriateness of using ATSs by pregnant / nursing should be taken by the doctor, assessing the possible risks.
How to take ACS
The drug under consideration is taken after a meal, the tablet or powder must be dissolved in 100-150 ml of liquid, and this can be pure water, tea, compote, and juice. Specific dosages and duration of admission of ATSs are determined by the physician on an individual basis, but there are also general recommendations for daily doses:
- if the treatment of cystic fibrosis is necessary and the patient weighs more than 30 kg, then the daily dose of ACS should be 800 mg( this is the maximum);
- treatment of cystic fibrosis in children aged 10 days to 2 years implies taking 50 mg of ACS 2-3 times a day;
- if a course of therapy is required against cystic fibrosis in children aged 2-5 years, the daily dose of the drug in question should be a maximum of 400 mg, which must be divided into 4 divided doses;
- treatment of cystic fibrosis in children older than 6 years is carried out by taking ACTS 3 times a day, the total daily amount should not exceed 600 mg.
Any other diseases whose treatment implies the use of ATSs also pass individually, but there are also the determination of the maximum daily doses:
- adults and adolescents with 14 years of age - 600 mg per day;
- children from 6 years - 400 mg( divided into two doses per day);
- children aged 2-5 years - 300 mg for two doses;
- children under 2 years of age - 50 mg per appointment, which should be 3 per day.
If the disease occurs in acute form, then the drug should be taken for 7 days, and in the case of a chronic course of pathologies treatment will be prolonged, it can last up to six months.
Possible side effects
In general, ATSTS is well perceived by the body, and side effects are extremely rare. The most frequent "pobochko" when taking this drug are diarrheal disorders - diarrhea, mild nausea, vomiting once, heartburn .In some cases, ATSC lowers blood pressure, which is accompanied by noise in the ears and headaches.
If the patient does not have an allergy to the main active ingredient ATSs, the body takes it normally, but in some cases the patient may develop a rash, reddening and itching of the skin.
If during the treatment of ATSC there is a deterioration in health status and the appearance of unexplained symptoms, then it is necessary to stop taking the medication and inform the doctor about what happened, most likely, the preparation will be replaced.If the digestive system disorders are intense, the patient will be symptomatically treated.
ACC is strictly prohibited to appoint concomitantly with tetracycline and its derivatives( the exception is only doxycycline) - this rule applies only to pediatric practice.
If at the same time a patient takes ACS and an antibiotic, then the interval between doses should be at least two hours.The drug under consideration is absolutely incompatible with the cephalosporin and aminoglycoside series.
It is not advisable to take antitussive drugs against the backdrop of treatment with ACC - sputum congestion in the respiratory tract is possible.
ACS is a common drug used to treat respiratory diseases.In the pharmacy, you can find analogues to him, which belong to the same group of drugs( mucolytics) and have a similar effect on the body - for example, Acysteine, Asibrox, Fluimucil, Acestad.But in any case, the appointment and selection of daily dosage / duration of the course of admission should be determined by a specialist.
Tsygankova Yana Aleksandrovna, medical reviewer, therapeutist of the highest qualification category