Actovegin: contraindications and indications for use

Actovegin is a broad-spectrum preparation aimed at the regeneration of various tissues of the human body.The medicine accelerates and stimulates metabolism in cells, increasing their vital potential.The instructions attached to the medicine contain all information about the properties, advantages and disadvantages of the drug.

Contents:

• Brief instructions for use Actovegin
• When is the drug used?
• Features of use Actovegin and contraindications
• How is vegetative-vascular dystonia treated?

Brief instruction on the use of Actovegin

Actovegin is a drug for improving the metabolic and regenerating mechanism inside cells.It stimulates the energy processes and functionality of the metabolism in the human body, helps restore intracellular level and tissue healing.

In addition, the drug enhances blood flow.Actovegin activates and stimulates the processes of renewal, improves the nutrition of cells.All this produces the resistance of tissues of various organs to hypoxia - oxygen starvation.

Actovegin is a drug based on the released protein from the calves' blood extract obtained by dialysis and filtration.

The active substance of the drug is the deproteinized hemoderivat of the blood of young calves.It was developed and patented by Actovegin Austrian company Nycomed.

Available in various forms:

• Cream for external use 5%;
• Ointment for external use 5%;
• External gel 5%;
• Eye gel 20%;
• Dragee with an amount of active substance 500 milligrams;
• Solution for injections with different doses - 400 milligrams, 200 milligrams, 80 milligrams of active substance;
• Solution for infusion with glucose and with sodium chloride;
• Tablets in a soluble coating with an active substance volume of 200 milligrams.

The main manufacturers of the drug are the famous pharmaceutical companies:

• KRKA, Slovenia;
• Nycomed, Austria;
• Sotex-Pharmaceutical Company, Austria;
• Hafslund, Austria;
• Unik Pharmaceuticals, India;
• Nycomed, Germany;
• Sotex FarmFirm, Russia.

When is the drug used?

Indications for the use of the drug are various conditions and diseases:

• Insufficient blood supply and blood circulation of the brain;
• Low level of oxygen in the blood;
• Ischemic stroke;
• Injuries to the head and brain;
• Decreased vascular tone with a violation of their functionality;
• Deviations in the nutrition of skin cells;
• Violation of the functionality of the valve apparatus;
• Ulcers of different degree and etiology;
• Burns;
• Treatment and prevention of radiation sickness;
• Damage to the cornea of ​​the eye of various etiologies;
• Damage to the sclera;
• Inflammatory processes of the cornea;
• Ulcers of the eyes;
• Consequences of corneal transplantation;
• Prevention of corneal abrasions, as a result of improper selection and wearing of lenses;
• Diabetic polyneuropathy;
• Placental insufficiency;
• Preventing early delivery;
• Postponed myocardial infarction;
• Cerebrovascular disease and its consequences;
• Radiation cystitis;
• Open wounds;
• Infection is post-traumatic.

All pharmacokinetics are based on the action of the physiological components of the drug.

Features of the use of Actovegin and contraindications

Depending on the dosage form of Actovegin and the disease due to which the medicine is prescribed, the doctor prescribes an individual method of application.The drug can be used in three ways: orally, parenterally, externally( topically).

According to the attached instructions:

• Dragee and tablets three times a day for 1-2 pieces;
• Intravenous and intra-arterial( depending on the severity of the disease and individual characteristics) initially 10-20 milliliters.In the subsequent appoint to 5 milliliters daily.
• Drip in the form of infusions once a day for 250 milliliters of the drug solution at a rate of up to 3 milliliters per minute.Course - no more than 20 days.It is forbidden to add other drugs to the solution of Actovegin.

Parenteral administration of the drug requires caution and monitoring.This is due to the possible development of an allergic anaphylactic shock.In addition, it is necessary to monitor the patient's arterial pressure level and the parameters of water-electrolyte metabolism.

• The gel is used according to the doctor's prescription for the purification and healing of superficial wounds and ulcers.Sometimes used for application in the form of bandages and compresses.Change bandages at least once a week.For wet surfaces - several times a day.
• The cream is used to treat wounds of different etiologies and improve their healing.
• Ointment Actovegin is used in the treatment of non-healing damage to the skin.It is recommended for prophylaxis of bedsores.
• Eye gel is prescribed by an ophthalmologist for the treatment of eye diseases.Usually 1 drop of gel is used three times a day.

The open package can be stored after opening for no more than 30 days.In the case of particles in the solution or the appearance of opacity, the drug should not be used.Side effects can occur due to hypersensitivity to the active substance of the drug.

In rare cases, allergic reactions may occur:

• Sweating;
• Hives;
• Edema;
• Drug-related fever;
• Increased body temperature;
• Pain in the heart;
• Emergence of tides;
• Hyperemia of the skin;
• Itching, burning and irritation in the area of ​​topical application.

Very rarely possible development:

• Shortness of breath;
• Hypo- or hypertension;
• Violations of some organs;
• Tachycardia;
• Frequent heavy breathing;
• Sore throat;
• Headaches;
• Vertigo;
• Spasms and muscle pain;
• Loss of consciousness.

In cases of dose excess and self-use of the drug, the following can be observed:

• Gastric colic;
• Abdominal pain;
• Nausea resulting in vomiting;
• Diarrhea.

Therefore it is extremely important to take and use the drug under the supervision of a doctor and only for its intended purpose.

There are some contraindications for the use of medication in treatment.For the drug Actovegin, the contraindications are:

• Age of the child up to 3 years;
• Hypersensitivity to Actovegin and its analogs;
• Heart failure with decompensation;
• Pulmonary edema;
• Anuria;
• Oliguria;
• Drinking water;
• Hyperchlorination;
• Hypernatremia;
• Diabetes mellitus( with the use of diffusions with glucose).

For all this, the drug is recommended for use during pregnancy to prevent phenoplacental insufficiency.However, if side effects are observed, the use of the medicine is immediately stopped.

Unauthorized use of Actovegin is prohibited, since with incorrect treatment with violation of the conditions of use, critical conditions are possible.The instruction for the preparation is familiarizing, not being a guide to action.

How is vegetative-vascular dystonia treated?

Many people face such a diagnosis as vegetative-vascular dystonia, a disease based on an imbalance in the autonomic nervous system.The disease is not life threatening, but it can often be a harbinger of other serious diseases.

If this is confirmed by a diagnostic examination, then treatment of the VSD with medications is required.Drug treatment is prescribed by the doctor, having carried out the necessary diagnostic tests, comparing the patient's complaints and the results of the tests.

Often in the treatment of VSD, the use of Actovegin is required, which interferes with energy cellular processes that affect the state of psychic energy.It is a great antioxidant that positively influences the regeneration of cells, blood supply and blood circulation of the brain and other organs.Actovegin has a medicinal effect on the body with VSD in the form of improving the metabolism of brain cells.

VSD is a disease that is often caused by the fear of death.Antidepressants, sedatives, antipsychotics and antioxidants, in particular, Actovegin, the combination in complex treatment helps to get rid of this disease.

Having coped with chronic stress, with fatigue, restoring balance in the body, patients recover from the VSD quickly.Additional measures in the favorable outcome of treatment are often adherence to diet and day, exercise, optimistic perception of one's life, setting goals, overcoming phobias, tempering the body, proper nutrition.

Learn about the treatment of VSD from the video.

Actovegin is a universal medicine that, when properly applied under the supervision of a doctor, can help even in the most "hopeless" case, improving the general condition of the patient.