Treatment of pancreatitis with medicines
Treatment of pancreatitis is largely determined by the severity of the process and includes several points. It is mandatory to follow a diet that helps to relieve the pancreas load and ensure her peace. Also, you can not do without taking medications.
For the treatment of pancreatitis in adults, various medications are used, which can only be prescribed by the attending physician.
Kinds of medicines
Drug treatment for pancreatitis is complex and involves the appointment of the following drugs:
- antispasmodics and analgesics for relief of pain syndrome;
- enzyme preparations for the alleviation of digestive processes;
- holinoliticheskih means used for painful forms of the disease;
- antiferment preparations for suppressing the activity of certain enzymes;
- antacids( phosphalugel, diamond) to reduce the production of gastric mucosa hydrochloric acid;
- antibacterial agents as anti-inflammatory therapy;
- H2-blockers block the histamine receptors of the gastric mucosa and thereby cause a decrease in the production of hydrochloric acid.
Enzyme preparations
After pain relief, as a rule, they begin treatment with enzyme preparations. Trypsin and lipase are used. Accept enzyme preparations with or immediately after eating. Their dosage is selected individually. At the same time pay attention to the patient's body weight, as well as the amount of fat in the stool.
These agents can be used to treat both acute and chronic inflammation in the pancreas in adults. In the latter case, it is often necessary to take these funds for life to maintain the digestive process.
From this group, you can distinguish Creon, available in capsules and containing amylase, pancreatin, lipase and proteases. It is distinguished by the dosage of the active substances included in it( 10,000, 25,000, 40,000 IU).Used as a substitute enzyme therapy for pancreatitis.
Spasmolytics and anticholinergics
These drugs are used to relieve pain. The most common antispasmodic is drotaverin( no-sppa), it refers to myotropic drugs. The therapeutic effect of drotaverine is to reduce the tone of the smooth muscles of the internal organs, to reduce the pain syndrome. In the acute period, the drug can be administered intramuscularly. Especially this method is recommended in the presence of vomiting( in this case drotaverin can be combined with a sedative neuroleptic).
Antacids
These preparations are aimed at neutralizing the action of hydrochloric acid, since they themselves have an alkaline reaction. They are effective for many gastrointestinal diseases, including pancreatitis. The most commonly used phosphalugel, diamond.
H2 blockers
The action of this group of drugs is aimed at suppressing gastric secretion. Among them, it can be noted ranitidine, famotidine. These drugs block H2 histamine receptors, inhibit the production of hydrochloric acid, which can be stimulated by histamine, nutritional load, irritation of the baroreceptors, acetylcholine and gastrin. More effective in pancreatitis famotidine. This drug belongs to the H2-blockers of the third generation and can be used in the treatment of both acute and chronic pancreatitis in adults.
Antibiotics
This group of agents is used as anti-inflammatory antibacterial therapy. This treatment can be prescribed for patients with fever, severe pain and prolonged vomiting.
As a rule, a combination of different antibiotics is used. The following combinations of antibacterial drugs can be used: aminoglycoside with cephalosporin, aminoglycoside with linkosomide, cephalosporin with aminoglycoside, cephalosporin with fluoroquinol.
Antiferment preparations
These drugs inhibit the activity of certain enzymes. Among them, two groups can be distinguished:
- inhibitors of proteolytic enzymes;
- inhibitors of fibrinolysis.
Among the first group, the most commonly used are gordoks, ингитрил, пантрипин and контрикал.These drugs suppress the activity of proteolytic enzymes, which are involved in the development of inflammatory processes in the pancreas.
In pancreatitis, antifoam agents are administered intravenously drip. In this case, allergic reactions to these drugs are possible( they can occur in about 10% of cases) and are most often expressed in allergic reactions( antihistamines are prescribed for their prevention).
There are some contraindications. In particular, these drugs are not recommended for individual intolerance of the components of the drug and increased sensitivity to them in adults. Some of them( ingitryl) can not be administered with increased blood clotting.
This group of drugs is used not only for the treatment of pancreatitis, but also for its prevention. For example, they can be prescribed for an operation on the biliary tract and stomach, since there is a risk of damage to the pancreas.
As you can see, the treatment of pancreatitis is rather complicated and therefore it should be prescribed only by a doctor.
