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Norma blood urea men and deviation from it

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Urea (Urea) blood test Transcript: norm and deviation

Urea (Urea) is the final product after the breakdown of proteins. It stands out from the body by the kidneys, that is the only body that is responsible for the complete elimination of urea from the body.

All the rest of her savings had already said that there are significant problems with the body that needs to be treated. Accordingly, for such control in medicine there is a certain blood chemistry, showing the final content of urea at the moment.

So it is possible to judge the health of the kidneys and their basic functions.

Urea is included in the composition of the residual blood nitrogen. This is a special substance, which respectively contain nitrogen, but the characteristics do not contain proteins.

To all this to the residual nitrogen properties include creatine, creatinine, uric acid, ammonia and others.

Most often, increasing urea indicates the presence of chronic diseases or occurrence of inflammation in the body.

If there is no rate of urea in the blood, as shown by biochemical analysis, it is necessary to immediately check the state of the kidneys. Perhaps it is their work gave an embarrassing failure in the study results. It should be noted that urea in their characteristics is still different from uric acid, so do not confuse this two substances, having received blood chemistry.

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research indicators

Biochemical analysis of blood shows whether there is a urea or not the norm. For his conduct is taken venous blood, as it is the most rich in all the necessary study materials.

In order to obtain reliable results it is recommended to take a mandatory analysis in the morning on an empty stomach.

It was at this point in the body and thus the blood there is no extra breaches and stimuli acting on the increase or decrease in urea.

the content of the norm differs only in the age category. For example, urea adult rate should be from 2.5 to 6.4 mmol / l. Children up to 14 years, the rate ranges from 1.8 to 6.4 mmol / L.

For elderly over 60 years the rate of urea should not exceed the limits from 2.9 to 7.5 mmol / l. All subsequent deviation from the norm should not be left unattended.

test results show the best doctor and consult in order to identify the cause of the time.

Increase or decrease in performance

Pass the biochemical analysis of blood and find out which urea - very little to make the correct diagnosis. The fact that the increased urea is not always a sign of disease.

For example, the increase may be insignificant in humans, is often used mainly protein foods. Also, these results are from those who are actively engaged in hard physical activity.

This happens especially in men.

As for the disease, the increased urea may be an indication of certain diseases. Quite often the cause of deviations from the norm can be bad food, excessive intake of alcohol and smoking, which is particularly detrimental effect on the liver and kidneys.

possible diseases

Deciphering the survey results will indicate the presence of kidney disease, which in turn are in violation of the excretory function.

This chronic and acute glomerulonephritis or renal amyloidosis.

In this scenario, you experience symptoms such as quickening or slowing the contrary urination, blood in the urine, high blood pressure, fatigue and weakness.

Biochemical analysis of blood will show a significant increase in creatinine, urea and all other components of residual nitrogen.

Another may be diseases such as heart failure, burns or hemorrhage, disorders resulting from blood access to the kidneys. In this case, the blood is not enough to clean the kidneys and that this leads to an increase in urea.

Thus, the interpretation of the results suggests that it is also necessary to pay attention to the kidneys.

Deciphering doctors can testify to such diseases that occur as a result of increase in protein breakdown. This long flowing chronic diseases, endocrine problems and malignant tumors.

The decline in

Biochemical analysis of blood can show not only an increase in urea, but also its significant reduction.

It may also result from the presence of certain diseases and disorders of the kidney. In this case the rate will also depend on the reasons for the decline and its results.

Thus, decoding indicates the presence of viral hepatitis, cirrhosis and liver cancer as well as other symptoms.

Since the liver is the major organ urea formation, the rate of its content in this organ depends on the work outputting body. Thus, all the functioning of complications affect the general health condition of the body. Biochemical analysis immediately shows a significant decrease in urea and decryption doctor will answer its causes.

It is worth noting that in this case the biochemical analysis can show and increased AST and ALT. Diseases of the digestive system may also be a cause of reduced urea. Not only can decrypt this point, but possible symptoms. For example, the sharp decrease in body weight, muscle weakness and fatigue, severe swelling and others.

Treatment

If the study shows that there are some deviations, and there is no rule of urea, it is necessary to take Meria treatment. To do this right already should seek medical advice.

After such determination cause increase or decrease, the doctor will prescribe appropriate treatment. In this case, all the action is directed to a "deletion" causes increase or decrease of urea, and after its recovery.

For this purpose various control methods, including the reception of various drugs and other drippers.

If we are talking about cancer, it will be assigned to appropriate therapy.

It all depends on what it was caused by the change in the indicator, because each may be quite different reasons, in the case and the lack of a serious disease.

Maybe just the wrong food or physical overload, and with what can not cope in a timely manner the body. Therefore, whatever the result of the analysis may have been, it is not necessary to engage in self-diagnosis and self-treatment.

A source: https://krasnayakrov.ru/analizy-krovi/mochevina.html

What is the normal level of urea in the blood in people?

Any kinds of metabolic processes in the body accompanied by the formation of the final products of metabolism and their intermediate metabolites. Determine their concentration allows blood chemistry. With respect to protein metabolism metabolites - the components of the residual nitrogen. One of them - urea in the blood. Explaining the importance of this indicator is devoted to this article.

As it is formed and circulates

The protein, which is part of all body tissues, is subject to constant synthesis and degradation.

The most powerful bodies involved in this process are the liver, heart muscle, striated muscles of the skeleton and the kidney.

The source of protein intake of food are amino acids entering the bloodstream during digestion. balance of protein and products of its metabolism is dependent on the status of these bodies.

urea circulation is as follows: the main depot protein - muscle tissue. In the process of life and energy for reductions constant protein breakdown occurs, in which the formed amino acids, creatinine and ammonia.

Since this substance is highly toxic to the body, the liver is its binding and neutralization by the formation of urea. Leaving the hepatic vein into the systemic circulation, urea must be excreted by the kidneys.

Thus, the body maintains a stable level of urea in the blood and produces self neutralization of toxic products of protein metabolism.

Important to remember! Urea - one of the final metabolites of protein metabolism. From the body the ability to synthesize and display it depends on the possibility of a natural cleanse the blood of toxic metabolic products!

How is

Determination of the concentration of urea in the scope of the biochemical blood analysis. His appointment suggests a study of rates of protein metabolism. In this it is not necessary to emphasize neither the doctor nor the patient. Each laboratory know a standard set of indicators included in the biochemical analysis.

To conduct the study needs about 10-20 ml of blood from a vein. After centrifugation and separation of the formed elements plasma (serum) is subjected to detailed testing involving various chemical reagents.

The result can be obtained within several hours. If the analysis examined plasma registers that urea are elevated, there is the feasibility of biochemical urine test to determine the concentration of urea.

This will give more information about the possible causes of deviations from the norm.

Blood urea - one of the main criteria of kidney function

performance Objectives

Normal blood urea represented a relatively wide spread of numbers. This is due to the impact on its performance, not only abnormal, but physiological and external and internal factors. In this case, registration of changes of indicators can be taken as a regular norm in these situations:

  1. The urea concentration in the plasma of adults is slightly higher than in children;
  2. Blood urea in women less than men of similar age group;
  3. In the elderly the amount of urea may be higher than that of young people;
  4. Strengthened food with a high content of protein in the diet causes increased level of urea;
  5. Inadequate fluid intake or increased its losses related to working conditions and lifestyle traits;
  6. Intensive muscle loads lead to higher levels of urea.

The average rate of the urea content (in mmol / l) in plasma is shown in Table.

Age Adults Newborns Children up to 3 years Children up to 10 years
urea norm 2,5-8,3 1,4-4,3 1,8-6,4 2,0-6,8

What does the rate increase

The greatest diagnostic value belongs to increase urea index. The more its norm is exceeded, the more pronounced structural and functional changes in tissues and organs, involved in protein metabolism. The main reasons for blood analysis indicates the increase of urea, and their detailed decoding are given in the table.

Group of causal factors specific diseases
kidney disease
  • Acute and chronic glomerulonephritis;
  • Acute and chronic pyelonephritis;
  • Urolithiasis in violation of the outflow of urine;
  • Renal amyloidosis;
  • kidney cancer;
  • Renal insufficiency of any origin.
liver disease
  • Viral and toxic hepatitis;
  • Cirrhosis of the liver;
  • Liver tumors;
  • Biliary tract disease accompanied by bile stagnation;
  • Hepatic or renal failure of any origin.
The pathology of the muscular system
  • Myositis and myonecrosis;
  • Progressive muscular dystrophy;
  • crush syndrome;
  • Gangrene of the limbs;
  • Restoration of blood flow in the limbs after prolonged ischemia (circulatory disorders).
Intoxication and medication
  • Poisoning by toxic substances (chemicals, poisons, salts of heavy metals, pesticides, etc.);
  • Infectious and septic purulent processes in the body;
  • Treatment with antibiotics tetracycline, sulfa and aminoglycoside series, furosemide, hormonal therapy.
other causes
  • A disadvantage of chlorine ions;
  • Dehydration on the background of diarrhea and vomiting;
  • Severe disease accompanied by increased protein disintegration with simultaneous dehydration (ileus, malignant tumor, leukemia).

Important to remember! Increase of urea up to two times higher than the norm is considered moderate and can be the result of any of these reasons. If urea are elevated in two or more times, it always speaks of renal disease, which led to severe renal failure and uremia. Therefore, analysis of urea - is one measure of kidney function!

Symptoms indicating a rate increase

In the context of clinical manifestations of high blood urea can be considered two options. In the first case we are talking about the appearance of complaints in healthy people without disease history. They can celebrate:

  • Headaches;
  • General weakness;
  • Lethargy and fatigue;
  • Increased sweating;
  • swelling;
  • Pain in the muscles and reduce their strength;
  • Decrease in intellectual abilities and memory;
  • Increase or decrease in the amount of daily urine.

In the second case, the symptoms increase urea levels are determined by the growing manifestations of the disease, which took place at the patient and caused the violation of its removal from the body.

This means that the degree of the general condition of these patients weighting can indirectly judge the progression and a progressive increase intoxication disease caused accumulation of toxic products of protein metabolism, containing ammonia.

Video transmission of kidney failure - the root cause of increasing urea:

What can cause decline

Very rarely, but sometimes you have to deal with situations where the rate of urea is not exceeded, but on the contrary, has not been achieved. Such an analysis suggests either a lack of protein in the body, or of deriving it from massive blood. This is possible in the circumstances:

And still advise to read:

What does it mean CRP in the blood test?

  • When pregnancy. Metabolic processes in the healthy mother and the fetus are directed on the synthesis of protein and not its decay, which is manifested decrease urea. Furthermore, in blood increases the amount of fluid that spreads further concentration of the compounds;
  • Food with low protein value;
  • Malabsorption of nutrients in the gut;
  • Excessive flooding the body and massive intravenous infusion;
  • After hemodialysis and other extracorporeal procedures detoxification (hardware artificial blood purification of toxic compounds in renal failure);
  • At deficiency of thyroid hormones;
  • Toxic liver damage and various phosphorus enzymopathies when the liver is unable to synthesize urea, which leads to a reduction of its concentration. This increases the level of other metabolites of protein metabolism.

Determination of urea level in the biochemical blood study relates to reliable landmarks in the assessment of protein metabolism and functioning of organs involved in this process.

The norm in the results - a reliable sign of their normal state.

If there are deviations from accepted standards is important to know how to decipher the figures given clinical and other tests.

A source: http://serdec.ru/krov/kakoy-normalnyy-uroven-mocheviny-krovi-lyudey

Urea is the norm in the blood of men over the age of

Content

Often in the biochemical study of urea is determined, the rate among men in the blood varies with the diseases of the liver and biliary tract and kidneys.

The indicator is the result of protein metabolism, so deviations can talk about his disturbed metabolism.

The fact that the reasons for the decline and increase the incidence of serious, so if you feel unwell, you must either go to a clinic.

Process appearance urea

the level of urea in the blood can not be seen in isolation, without taking into account other parameters blood test. An integrated approach allows us to more accurately orient with the diagnosis and follow-up.

Here the urea scheme:

  1. Organs and tissue for the activity using oxygen, glucose and other substances.
  2. After the process is complete, the cell appear waste products, including ammonia.
  3. He is detoxified by the liver, through which all the blood.
  4. At the exit there is urea in the blood.
  5. In order to avoid any excess of the substance, blood passes through the kidneys, and outputs the main part of the outside of urea.
  6. Some amount remains in the buffer system of the body.

The rate of urea in the body and removing it out is approximately the same, thus maintaining index on one and the same level.

Urea (the second name of the blood component) is determined by examining the venous blood. Letting the analysis takes place on an empty stomach, because the presence of lipids in the serum does not informative analysis. The patient receives the result of the next day.

Biochemical analysis of blood with the determination of urea carried out periodically during the medical examination from the work passage medical examination on the driver's certificate and the appearance of complaints. Doctor to facilitate its task appoints general and biochemical blood test.

That is, under any circumstances can be fundamentally important level of urea:

  • When the pain of the big toe and ankle (may be a manifestation of urate gout or infarction).
  • As a preventive measure in order to avoid gout in the presence of disease in close relatives.
  • When the complex examination of the urinary system.
  • If you are diagnosed degree of disorders of the cardiovascular system.
  • If there is pain in the lower back on the right or the left, impaired urination, change in urine color.
  • In order to control the patient's condition after conservative treatment of cancer.
  • If you suspect a rheumatic disease (pain and swelling in the joints, recently transferred angina).
  • When a diet change (starvation diet).
  • Intoxication of various origins.

The basis power athletes is increasing protein intake because it heavily consumed during exercise. Therefore, they are examined more often than other categories of people.

Assigning pregnant women, a gynecologist analysis can determine the level of growth of the fetus in the mother's kidney burden.

Studies of modern scientists have established the relationship between the level parameter and the blood group: above all, he in those with 3 group.

Methods for determining

urea concentration gives an indication of renal function and liver, since its release occurs in the urine, and the rate set indicator in the secondary medium.

The end result of research affected by several factors: the nature of food, alcohol, smoking, stress, physical activity and the level of fatigue. Therefore for a reliable result it is necessary to give up fatty foods and all other listed items.

All the methods for determining the urea is divided into several groups:

  • gasometrical ways;
  • photometers;
  • enzyme;

Laboratories usually choose for themselves the method that is convenient for them financially, as well as the most accurate and informative.

For the ordinary citizen it does not matter what principle is the basis for determining the parameter, but general information about it can not hurt:

  • Gasometrical methods are now used infrequently because they do not allow to accurately determine the value of indicators. Its essence lies in the fact that the sample is added sodium hypobromite solution which promotes oxidation of urea. This provokes the release of nitrogen, the amount of which is measured and correlated with the original urea level.
  • Photometric methods based on the fact that when connecting the patient's blood sample with certain substances staining solution occurs in any of color of varying intensity. This sample is compared with the existing control samples, then the result is registered.
  • The enzymatic method is based on the fact that the enzyme urease decomposes urea level is measured more substances formed.

Norm and deviation

As for the concentration of the substance in various categories of the population, the rate of urea in the blood of men and the elderly - is higher in children and women - below.

Specific figures are as follows:

  • infants - 1,2-5,3 mmol / l;
  • children up to 14 years - 1.8 - 6.5;
  • for women the normal rate - 2,3-6,6;
  • Healthy men have 3,7-7,4 mmol / l;
  • elderly - 2,8-7,5 mmol / l;

Male analysis has higher value due to the fact that the nature of their power dominates animal protein in the form of meat, and that is reflected on the form.

If the analysis of blood urea slight deviation occurs parameter, this can be caused by overeating or temporary effect factors. But if there is a significant violation, it is necessary to find the cause of such an analysis.

Lowering and raising of the urea takes place for their own reasons.

Decrease the numerical value of the indicator can be observed under the following conditions:

  • nature of power when excluding or deficient protein (diet, starvation);
  • the liver, leading to disruption of the metabolism of urea;
  • liver inflammation (hepatitis), cirrhosis (destruction of body tissue);
  • disruption of the endocrine system (eg, thyroid);
  • with malabsorption syndrome, which disrupts the absorption of amino acids (which are structural components of protein);
  • hepatitis combination with tissue necrosis;
  • poisoning by arsenic or phosphorus;
  • pituitary hyperfunction (results in acromegaly, which is manifested disproportionately long limbs and developed front part of the skull);
  • excess intake of liquid;
  • after the artificial blood purification (hemodialysis).

The reasons for lowering the level is insufficient intake in the protein body or breaking its absorption.

Increasing the level of urea is a sign of the following abnormalities:

  • Renal dysfunction (inflammatory and infectious lesions, organ failure).
  • Violation of urine excretion (tumor, adenoma, urolithiasis).
  • Diseases of the cardiovascular system (heart attack, heart failure).
  • Bleeding of the digestive tract.
  • Diabetes.
  • Hyperthyroidism.
  • The high content of protein in the diet.
  • Leukemia, leading to increased protein catabolism.
  • Excessive physical strain.
  • The loss of body fluid (supplied by vomiting, diarrhea).
  • Large area burns.

In determining the rate of urea in the blood of men indicates that the kidneys are functioning normally, there is no malabsorption substances in the digestive tract, there is no process of atrophy in muscle tissue body.

Signs of metabolic system of urea are weakness, headache, muscle weakness, blurred vision, indigestion, although they are not specific.

If any of the signs should request the appropriate specialist. He will appoint necessary research, analyzes, if necessary - treatment.

A source: http://BolezniKrovi.com/analizy/biohimicheskij/mochevina-norma-u-muzhchin-v-krovi.html

Why increased urea in the blood, what does it mean?

Urea - the end product of protein metabolism, and more specifically amino nitrogen. Urea is produced by the liver during protein synthesis, is removed together with urine by the kidneys.

The residue of this component in the blood gives an indication of the effectiveness of the kidneys, and any deviation from the norm concentration of urea should guard.

Increased urea in the blood analysis usually shows a chronic or acute kidney disease. It is often accompanied by kidney disease at the same time with an increase in the blood concentration of urea it content decreases in urine (due to poor functioning kidneys urea in the blood begins to accumulate).

Of note is the fact that urea and uric acid - a different matter. Uric acid is mainly produced by the decay of complex nucleic acids.

The norm in blood urea

In adults, the level of urea is determined by biochemical analysis of blood. To do this, blood is taken from a vein located at the elbow. The results to be valid it is recommended to carry out blood donation in the morning and on an empty stomach (only allowed the use of water).

Normal value content of urea is determined by the age and gender of the person.

  • newborn 1,7-5,0;
  • children under 1 year of 1,4-5,4;
  • children under 15 years of 1,8-6,7;
  • adult women 2,0-6,7;
  • adult men 2,8-8,0.

Quantitative level of urea in the blood depends on three factors:

  • significant levels of amino acids in proteins exchange body (from which the amount of ammonia produced depends);
  • liver condition (independent transformation into urea ammonia);
  • renal (urea withdrawal from the body).

During high protein intake of food, and with a substantial destruction of proteins in the body, it increases the formation of ammonia, and hence the urea.

When this analysis is prescribed?

This index gives doctors an idea of ​​renal excretory function - their ability to remove unwanted substances in the urine. According to its concentration in the blood can talk not only about the work of the kidneys, but also the state of the musculoskeletal system and the liver.

Indications for the implementation of the laboratory test are:

  • all forms of ischemic heart disease;
  • systemic connective tissue disease;
  • hypertension (regardless of the duration of its existence);
  • detection of deviations in the overall analysis of urine in the screening examination;
  • liver disease accompanied by dysfunction of (hepatitis, cirrhosis);
  • suspicion of renal inflammatory or infectious disease;
  • diseases of the gastrointestinal tract which are characterized by decreased absorption of food ingredients (celiac disease).

The urea concentration in the blood is:

  1. Indicator of renal excretory function, ie the ability to eliminate urine together with unnecessary body substances.
  2. Indicator muscle condition. This is due to the fact that the protein, resulting in the collapse of which appears urea is contained mostly in the muscles.
  3. Evidence for the effectiveness of the liver. After all the ammonia produced from urea in this organ.

Thus, the urea in the blood - a significant indicator of hepatic, kidney and muscle.

Reasons for the increase in blood urea

Why blood urea increased, and what does it mean? In fact, there are many reasons because of which the figure may be higher than normal. They do not necessarily be associated with some deviations in the life of the organism.

The reasons are not indicative of the disease, but which can be increased urea in the blood of adults:

  1. As a result of receiving certain medications, e.g., Lasix, Eutiroksa, Tetracycline, Corticosteroids, sulfonamides, cephalosporins, anabolics, Neomycin, steroids, salicylates, androgens.
  2. Excessive consumption of protein foods, or vice versa starvation.
  3. Because of the intense exercise.
  4. Nervous stress.

One of the main reasons for the increase of urea in the blood is associated with impaired renal excretory function, which can be observed in a number of diseases:

  • Acute renal failure in which the urea first increases and then creatinine, and is at least 10 mmol / l;
  • Blockage of ducts urinary calculi or neoplasm;
  • CRF (parallel to the concentration of uric acid, creatinine, cystatin C);
  • Pyelonephritis and glomerulonephritis;
  • Reduced blood supply to the kidneys due to dehydration, shock, heart failure, myocardial infarction.

Also enhanced protein breakdown, and, accordingly, increased urea biosynthesis (produktsionnaja azotemia) cause many human diseases:

  • Hematological disease (leukemia, leukemia, malignant form of anemia, hemolytic jaundice).
  • Serious infections, including gastrointestinal (dysentery, typhoid, cholera).
  • bowel disease (obstruction, peritonitis, thrombosis).
  • Burn disease.
  • Neoplasms of the prostate gland.
  • Shock.

To determine the nature of the disease, a doctor examines the serum urea dynamics.

Thus the patient is sent for further urine to determine index urea in this material.

For reliable conclusions take into account the level of red blood cells, lymphocytes, blood sugar levels and other indicators and symptoms to assess the patient's overall health.

symptoms

Increased urea levels in the blood of men and women can be identified by the following characteristics:

  • lower back pain;
  • the problem with the outflow of urine, it appears too much (polyuria) or very little (anuria);
  • high blood pressure;
  • swelling;
  • the formation of blood in the urine and protein.

In medicine, clinical signs of increasing the concentration of urea in the blood called a special term - uremic syndrome.

How to treat elevated blood urea

If the blood chemistry analysis showed this pathology in a patient, the doctor, first of all, try to find out exactly what it was the root cause, in other words, you will need to pass an additional examination in order to identify the main disease. And, of course, will need to retake a blood test.

At home, the decline in urea level is achieved by reducing meat products from the daily diet, in this case, the emphasis needs to be done on fruit, vegetables, cereals and fruit. It is recommended to drink a decoction of rose hips, juices, which are used for preparation of fresh fruit and vegetables, diuretic tea.

But all is good only if the person is not detected any serious diseases. In the same case, if the increase in blood urea - is a consequence of the disease, then to solve the problem of urea will be a doctor. Moreover, the increase in this index - it's just a reaction to the problem, it is a consequence.

A source: http://simptomy-lechenie.net/pochemu-v-krovi-mochevina-povyshena/

Urea in Blood: functions, norms, deviations

Despite the consonance of the terms "urea" and "uric acid", they are classified as different substances.

So how to understand what the urea and how does it differ from the acid? If uric acid - the result of cleavage of purines, the blood urea formed during the decomposition of complex proteins and amino acids
Urea is produced in the liver for disposal of ammonia - the end product of protein metabolism.

In diagnostics it is used as an indicator of the liver and kidneys. According to her trial and other violations of the body. Slight variations - this is normal, but if the urea is significantly increased or decreased in the blood - is an alarming signal for the medical personnel.

Facts about ammonia and urea

Urea what is it? It is among the group of substances called residual blood nitrogen. These are products of protein metabolism, which include nitrogen, but they do not belong to the proteins.

These elements are:

  • Uric acid,
  • creatine,
  • creatinine,
  • Ammonia,
  • Urea.

Ammonia - a toxic substance, therefore, the body tends to recycle it into a harmless urea. Urea produced in the liver.

From there it goes into the blood to transport in the kidney, after she was expelled from the body in urine.

Urea has a few names: carbamide, diamide of carbonic acid, not uric acid - it is quite another matter.

Urea is formed quickly and in the same accelerated pace excreted by the kidneys. All thanks to the simple structure of this element.

It consists of:

  • Carbonic acid,
  • 2 molecule of ammonia.

That is why the human body, its minimum level.

Despite its relative harmlessness, blood urea at high concentrations of toxic and dangerous. It easily overcomes the cell membranes of the liver, kidney and spleen.

Thus it "drags" water, thereby increasing the cell, and they can no longer function normally (hyperhydration cells).

Therefore, the level of carbonic acid diamide is judged on the status and operability of parenchymatous organs (liver, kidney, spleen).

Functional purpose

So what is needed urea? For nothing. With food in our body receives the vitamins and trace elements. In the process of digestion formed - ammonia. It is toxic and therefore dangerous for the organism. To neutralize it formed urea in the liver. It is the end product of protein metabolism, and with its help the body get rid of surplus nitrogen.

Rates for different age groups

Development of urea and its excretion from the body - an ongoing process. Its level in the blood must meet certain standards. The table shows the rate of urea in the blood by age groups.

Age group Blood Urea rate (mmol / l)
grudnichki 1,1 — 8,8
Children up to 14 years 1,8 – 6,4
Adults up to 60 years Women 2,3 – 6,6
men 3,7 – 7,4
People over 60 years old 2,9 – 7,5

According to our tests, the healthy adult human blood urea level of 660 mg / L - about 4 mmol / L. Daily kidneys displayed 20-35 g of the diamide of carbonic acid, that is 333,6-587,7 mmol.

With age, the rules of urea increases. This is due to a decrease in kidney performance. Yes and gender indicators are different: men level is always higher than that of women.

Urea in blood chemistry

Although urea and the final product is subject to removal from the body, it is still involved in a number of physiological processes.

Biochemical analysis of blood urea is important:

  • On it is judged as the kidneys eliminate substances
  • In the liver, the synthesis of urea, so low concentration suggests hepatic diseases about,
  • Intensive protein breakdown leads to an increase in blood urea. This means that for this indicator are judged on muscle condition.

If a patient is concerned about the following symptoms, the physician is required to appoint a delivery biochemical analysis of blood:

  • Fast fatiguability,
  • Lack of appetite,
  • Heaviness in the legs,
  • cramps,
  • Back pain and bone,
  • Insomnia,
  • itching
  • Frequent urination,
  • Urine has changed its color. She became colorless or dark. It is observed foam and even blood.

How is the analysis?

When the biochemical analysis of blood from the patient is made from a vein. To study were as accurate as possible is necessary to adhere to the following guidelines:

  • sampling is carried out in the morning,
  • Letting analysis conducted on an empty stomach,
  • On the eve eliminate physical and emotional stress,
  • During the day, you need to give up alcohol and heavy meals.

As a preventive measure analysis of blood urea 1 shall once a year, and for the diagnosis - in the direction of a health professional.

blood urea content can then fall, then rise again. The level of influence a variety of physiological processes, some of them are harmless and they are considered the norm, while others - the threat to human health and life.

Secure reasons for deviations

With intense physical activity level of urea increased, so in men the level above, in connection with the development of muscles. It plays an important role and power. Menu poor in protein foods to reduce the urea concentration, as well as excessive consumption of foods rich in proteins improves.

chlorine deficiency in the human body caused by the rejection of salt consumption, urea production provokes intensive.

During pregnancy the body's need for vitamins, proteins, fats and minerals doubles. This is reflected in biochemical indices. Since the consumption of protein in the growing fetus increases in serum urea decreased.

When all of these factors there is a slight deviation from specifications. Over time, the urea level is stabilized independently, without outside interference.

pathological symptoms

Increased urea levels can be an indication of disease progression.

These pathological processes include:

  • Inflammation and kidney infections (pyelonephritis, tuberculosis, amyloidosis, hypertension)
  • Obstruction of the ureters,
  • Poor blood supply to the kidneys,
  • Dehydration is a longer,
  • High level of protein breakdown,
  • Vascular insufficiency,
  • Uremic syndrome (chronic renal failure caused by the accumulation of toxic substances in the body).

Low urea in the blood, what is it? This is a rare phenomenon that occurs as a result of:

  • A rigid diet, protein deficiency,
  • Hepatic coma,
  • Hepatic cirrhosis and hepatic insufficiency
  • Irregular secretion of the thyroid gland,
  • Malabsorption - amino acids are poorly absorbed the intestines,
  • Poisoning by arsenic or phosphorus,
  • Acromegaly - high level of growth hormone (somatotropin),
  • Dialysis consequence.

Reduced diamide of carbonic acid content in the blood is rarely the case, therefore will be described only the high-level symptoms of this element.

Symptoms of imbalance of urea in the blood

Uremia - this intoxication nitrogen slags that have accumulated as a result of improper kidney. One of these toxins is urea. Its highest level in the blood affects the well-being of a person. Initially, the patient feels:

  • Fatigue,
  • General weakness,
  • Headache.

Without appropriate response aggravated clinical picture:

  • Poor eyesight,
  • Liver dysfunction,
  • Soreness in the joints,
  • High blood pressure,
  • Deficiency of iron in the blood,
  • nausea,
  • Diarrhea,
  • oliguria - decreased amount of urine,
  • The tendency to bleeding,
  • Plaque on the skin appear. This uremic "powder."

What is uremic raid? Accumulate in the body, urea as a mineral substance, simply emerges on the surface of the skin.

External signs of increasing urea:

  • Brittle nails and hair,
  • Dry skin,
  • Frequent urination or no,
  • The skin starts to smell the urine due to ammonia toxicity.

If nothing is done, then the brain cells start to die, there will be neurological and psychological disorders.

What to do?

urea level depends on the age and metabolism. Therefore, you should take appropriate measures:

  • Monitor the water balance,
  • Choose the appropriate diet,
  • Do not forget the timely meal,
  • To live an active lifestyle.

Drinking regime plays an important role in the proper functioning of all systems. The norm is to drink 2 liters of water in nature. Preference is better to give a mineral water without gas.

You should not go on about fashion, reducing daily calories or starve. All these measures may aggravate the condition of the body and lead to an increase in urea. Urea in the blood is normal, if you try to eat a day not less than 6 times, and fasting days to spend not more than 1 time per week.

If the tests show a high concentration of urea, then you should reconsider your diet.

To the urea was normal, experts recommend to increase the consumption of the following products:

  • Lean rabbit meat, chicken, turkey,
  • Seafood, in which the fat content does not exceed 8%
  • eggs,
  • milk and milk products,
  • Vegetables,
  • Fruits,
  • Vegetable oil and olive oil,
  • Pasta and cereals are not more than 1-2 times a week,
  • Homemade marmalade, jelly, jam, jam,
  • Juices, infusions, decoctions,
  • Weak tea and coffee.

It is prohibited to use:

  • Fatty meats and fish,
  • Sausages,
  • smoked,
  • Salt,
  • Canned,
  • Carbonated drinks,
  • Alcohol,
  • mushrooms,
  • Sorrel,
  • Cauliflower,
  • Strong coffee and tea.

When the results appears in the form of urea and 10 mmol value above assistants resorting to drug therapy. In these figures the body is unable to cope on their own.

Drugs that can help the body excrete urea, does not exist.

You can help the patient infusion therapy, but the only way to replace the kidney - is dialysis or kidney transplantation.

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A source: https://KardioBit.ru/analizy/analizy-krovi/mochevina-v-krovi-funktsii-normy-otkloneniya

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