Disputituitarism is pubertal and youthful

Disputituitarism pubertal - youthful( okolopubertatny basophilism, hypothalamic syndrome of puberty, youth hypercorticism, obesity with pink strias) - neuroendocrine syndrome, which manifests increased mental and physical fatigue, abnormal increase in body weight, menstrual irregularities in girls and gynecomastia in young men. This syndrome develops in the age of the physiological activation of the system: pituitary - hypothalamus - peripheral endocrine glands

Causes

In most reported cases, dispituitarism puberty - Junior observed in genetically determined constitutional - exogenous obesity. By provoking factors of development dispituitarism puberty - youth include: mental and physical trauma, infectious diseases( including CNS), a sharp decrease of habitual physical activity, sexual initiation. Repeated angina and chronic tonsillitis very often accompany dyspeptuitarism puberty - juvenile. However, in most patients, the immediate cause of this disease can not be established

course and symptoms of this syndrome occurs equally in both girls and boys at the age of 12 to 23 years( in most cases between 15 and 18 years).A characteristic feature is tall( more often in young men).Uniform obesity of the second - third degree is observed. On the skin of the thighs, abdomen, chest, shoulders there are multiple red or pink stretch bands( often superficial, short).In girls, there is a violation of the menstrual cycle, and in young men gynecomastia( an increase in mammary glands).Sexual development can be slow, normal or accelerated. Quite often notes transient hypertension( more often in boys)

Diagnostics

on electroencephalogram( EEG) - there are signs of impaired functioning of the nonspecific structures of diencephalic region and midbrain. On the radiograph of the skull - in the area of ​​the "Turkish saddle" there are areas of calcification of the dura mater, as well as signs of intracranial hypertension. In a number of patients, the function of the adrenal cortex was increased, glucose tolerance was impaired, and the hyperinsulinism was present. The course of this syndrome is in most cases benign.

dispituitarism puberty - Youth must be differentiated from syndrome Cushing - Cushing and pituitary adenomas

Treatment

For the normalization of body mass while reducing other symptoms of the disease, attributed to increased exercise and low-calorie diet. In the treatment in a hospital designate a specially designed diet that is in daily use from 1200 to 1500 kcal, of which: 80 - 120 g carbohydrates, 70 - 80 grams of fat, 80 - 100 grams of protein.

In addition, diuretics, spironolactones, anorectic agents( desopimon, fepranone, etc.), adiposine, thyroid preparations are prescribed. In the presence of symptoms of sexual insufficiency, young men are assigned a chorionic gonadotropin 2 - 4 r. In a week to 1500ED, courses of three to four weeks. To improve the functional cerebral activity, it is prescribed cerebrolysin, nootropil, cavinton, stugeron, cynarizine( courses 1 to 3 months, 20 to 40 injections per course).

Treatment of adolescent forms of obesity among other things, is the prevention of the development of hypertension, diabetes and infertility .

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