Omnik: what reviews of the drug are there?

Omnic

Omnic selectively and competitively blocks postsynaptic α1A-adrenergic receptors located in the smooth muscles of the prostate glands, bladder neck and prostatic urethra, as well as α1D-adrenergic receptors, mainly located in the urinary body bubble.

This leads to a decrease in the tone of the smooth muscles of the prostate gland, bladder neck and prostatic urethra and an improvement in detrusor function. This reduces the symptoms of obstruction and irritation associated with benign prostatic hyperplasia.

As a rule, the therapeutic effect develops 2 weeks after the start of taking the drug, although in some patients, a decrease in the severity of symptoms is noted after taking the first dose.

Omnik's ability to affect α1A-adrenergic receptors is 20 times greater than its ability to interact with α1B-adrenergic receptors, which are located in the smooth muscles of blood vessels. Due to this high selectivity, the drug does not cause any clinically significant decrease in systemic blood pressure both in patients with arterial hypertension and in patients with a normal baseline HELL.

Pharmacokinetics

Suction

After oral administration, tamsulosin is rapidly and almost completely absorbed from the gastrointestinal tract. The bioavailability of the drug is about 100%. Absorption slows down somewhat after eating. The same level of absorption can be achieved if the patient takes the drug every time after the usual breakfast.

The pharmacokinetics of tamsulosin is linear. After a single dose of the drug orally at a dose of 400 μg, the Cmax of the active substance in plasma is reached after 6 hours.

Distribution

After repeated oral administration of the drug in a daily dose of 400 μg, Css is reached by the 5th day, while its value is 2/3 higher than the Cmax value after a single dose of the drug.

Plasma protein binding - 99%. Vd is insignificant and amounts to 0.2 l / kg.

Metabolism

Tamsulosin is slowly biotransformed in the liver to form less active metabolites. Most of the active substance is present in the blood unchanged.

In experimental studies, the ability of tamsulosin to slightly induce the activity of liver microsomal enzymes was revealed.

Withdrawal

Tamsulosin and its metabolites are excreted mainly in the urine, 9% of the dose is excreted unchanged.

T1 / 2 with a single dose of 400 mcg of tamsulosin after meals - 10 hours, after multiple doses - 13 hours.

Source: https://ProTabletky.ru/omnic/

Omnic

Omnik is a drug that is effectively used to treat impaired urinary dysfunction, accompanied by benign prostatic hyperplasia.

The active ingredient - tamsulosin - does not affect the muscles of the walls of blood vessels, thereby not exposing the body to a decrease in blood pressure.

The mechanism of action of the drug leads to relaxation of the smooth muscle fibers of the neck and bladder, which enhances the flow of urine even with a significant volume of the prostate gland.

This effect does not appear on the walls of blood vessels due to the pronounced selectivity (selectivity) of tamsulosin.

In the vessels there is a subtype of alpha - adrenergic receptors - alpha 1 B receptors, taking alpha 1 A - blockers does not cause a significant decrease in blood pressure in patients.

Clinical and pharmacological group

Α1-adrenergic receptor blocker; a remedy for the symptomatic treatment of benign prostatic hyperplasia.

Conditions of dispensing from pharmacies

Dispensed by prescription.

Prices

How much does Omnik cost in pharmacies? The average price in 2018 is 400 rubles for 10 capsules.

Release form and composition

Omnik comes in the form of modified-release hard gelatin capsules (size # 2, orange body labeled "701" and olive green cap labeled "0.4"). The capsules contain:

• The active substance is 0.4 mg of tamsulosin hydrochloride (in the form of white granules with a light yellow tint);
• Auxiliary components - calcium stearate, indigotin, gelatin, iron oxide red, polysorbate 80, talc, MCC, iron oxide yellow, titanium dioxide, sodium lauryl sulfate, methacrylic acid copolymer (type C), triacetin.

In blisters of 10 pcs., 1 or 3 blisters in a box.

Pharmacological effect

Omnic is a specific blocker of alpha1-adrenergic receptors found in the fibers smooth muscles of the prostatic urethra, bladder neck and prostate glands. The use of the drug helps to reduce the tone of smooth muscles of the urethra, bladder and prostate gland, which leads to a significant improvement in the outflow of urine.

The active component of the drug has a high selectivity (does not affect smooth muscle fibers of the walls of blood vessels), due to which the medication does not provoke a systemic decrease in arterial pressure.

Omnic has 100% bioavailability. The maximum concentration of the active substance in the blood is observed 6 hours after oral administration. The drug and its metabolites are excreted exclusively by the kidneys. Approximately 9% of the drug is excreted unchanged. The half-life of the drug is 10 to 13 hours.

Indications for use

Dysuric disorders in benign prostatic hyperplasia (treatment).

Omnik - okas and Omnik: what's the difference?

Omnic has an undesirable side effect of retrograde ejaculation (the throwing of semen into the bladder during orgasm).

Since Omnik-Okas has a gradual release of the medicinal substance due to its structure, normal ejaculation is maintained. Therefore, it is reasonable to use Okas in men who have a fairly active sex life, and for whom the fact of the presence of ejaculate at the end of the sexual act is important.

Note that more often in treatment regimens for exacerbation of prostatitis, tamsulosin is prescribed in a short course, from 10 days to 1 month, so it is convenient to buy the Okas form in packaging for exactly 10 days. The disadvantages of Okas include the price, it costs more than the usual Omnik.

Contraindications

• hypersensitivity to the constituent components of the drug;
• severe liver failure;
• orthostatic hypotension (pressure drop with a sharp change in body position).

The use of Omnik requires caution in patients with severe renal failure.

Dosage and method of administration

The instructions for use indicate that Omnik should be taken 1 time per day, 1 capsule (0.4 mg). The capsule of the drug should be swallowed whole without chewing.

Side effects

During therapy with the use of Omnik capsules, the following side effects were occasionally observed:

1. From the reproductive organs: retrograde ejaculation.
2. From the digestive system: nausea, vomiting, stool disorders.
3. From the side of the skin: urticaria, itching, angioedema.
4. From the side of the central nervous system: dizziness, headache, general weakness (very rare).
5. From the side of the cardiovascular system: tachycardia, orthostatic hypotension.

Overdose

In clinical practice, there have been no cases of acute intoxication with the drug Omnik. When using excessively high doses of the drug, theoretically, the following symptoms may occur:

• acute form of arterial hypotension;
• compensatory tachycardia.

As a treatment for the consequences of an overdose, it is recommended to put the patient to bed and introduce vasoconstrictor and volume replacement drugs. To prevent further absorption of the active element, you can rinse the stomach and take sorbents or osmotic laxatives. You should also constantly monitor the functioning of the kidneys.

special instructions

Before you start using the drug, read the special instructions:

1. Use with caution in patients prone to arterial hypotension, with severe liver dysfunction.
2. Before starting tamsulosin therapy, the patient should be examined for other diseases that can cause the same symptoms as benign prostatic hyperplasia. Before starting treatment and regularly during therapy, a digital rectal examination and, if necessary, determination of a specific antigen of the prostate should be performed. In patients with impaired renal function, changes in the dosage regimen are not required.

During the period of treatment, it is necessary to refrain from engaging in potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.

Drug interactions

When using the drug, it is necessary to take into account the interaction with other drugs:

1. Diclofenac and indirect anticoagulants slightly increase the rate of tamsulosin elimination.
2. In in vitro studies, no interaction was found at the level of hepatic metabolism with amitriptyline, salbutamol, glibenclamide and finasteride.
3. With the simultaneous use of tamsulosin with cimetidine, there was a slight increase in the concentration of tamsulosin in the blood plasma, and with furosemide, a decrease in the concentration; with other α1-blockers - a pronounced increase in the hypotensive effect is possible.
4. Other α1-blockers, acetylcholinesterase inhibitors, alprostadil, anesthetics, diuretics, levodopa, antidepressants, beta-blockers, slow calcium channel blockers, muscle relaxants, nitrates and ethanol can increase the severity hypotensive effect.
5. Diazepam, propranolol, trichloromethiazide, chlormadinone, amitriptyline, diclofenac, glibenclamide, simvastatin and warfarin do not alter the free fraction of tamsulosin in human plasma in vitro. In turn, tamsulosin also does not change the free fractions of diazepam, propranolol, trichloromethiazide and chlormadinone.

Reviews

We have selected some reviews of men who used the drug Omnik:

1. Semyon. I have been taking Omnik for the second year already. I drink Prestans even longer because of the pressure. The pressure is never below 120/70 mm Hg. did not go down. Last year, kidney stones were crushed, after which every 2 months I go to the clinic for tests. The doctor said that it is necessary to monitor the kidneys, since I take Omnik capsules. A year has passed, and the analyzes are in perfect order. It would be good if there were drugs from the Forte series. One tablet a week is better than seven.
2. Valera. We have been living with my wife for 25 years. Two were raised. As she entered menopause, we no longer needed contraception. And then the prostate adenoma joined, the problems began with urination and potency. The treatment took place under the supervision of a urologist. He was drinking Omnik and some other medicines, when suddenly his wife became pregnant. I have never read that tamsulosin has such an effect.
3. Victor. I have been taking omnik for a year already as prescribed by a doctor, the result is good, it worked immediately, urination is abrupt improved, the severity during intercourse weakened, I think due to the effect of the drug on muscle tissue urethra. Sperm secretion is normal, I am taking befungin at the same time, after surgery for stomach cancer for 5 years. Befungin - chaga inhibits the growth of cancer cells, what I mean, and the adenoma is close to this. Therefore, prevention will not hurt anyone, plus daily exercise. I wish everyone a long active life. I am 58 years old.

Analogs

Omnik analogs are:

• According to the active substance - Sonizin, Taniz-K, Proflosin, Tamsulosin, Tamzelin, Hyperprost, Revokarin, Fokusin, Omsulosin, Tamsulosin;
• By the mechanism of action - Alfuzosin, Urorek, Dalfaz retard, Alfuprost MR.

Before using analogs, consult your doctor.

Storage conditions and shelf life

Omnik should be stored in a place protected from access by children at a temperature of 15˚C to 25˚C.

Shelf life is 4 years. The drug is dispensed from pharmacies with a prescription.

Source: http://simptomy-lechenie.net/omnik/

Omnik: what reviews of the drug are there?

Omnik tablets can be useful for a man who suffers from benign hyperplasia of an organ such as the prostate gland. Hyperplasia is an enlarged prostate.

It is associated with aging processes and is present in a significant proportion of men over the age of 60.

This ailment has nothing to do with oncological processes, its symptoms do not always progress, on the contrary, hyperplasia responds well enough to medical treatment.

Stages of benign hyperplasia and their treatment

The main problem with prostate adenoma is that the disease negatively affects the process of urination, this can lead to a number of severe disorders in the body (vesicoureteral reflux, stones in the bladder and etc.). Therefore, the first manifestations of hyperplasia need to be paid attention to and go to the doctor in order to receive timely treatment.

The clinical classification of prostatic hyperplasia identifies several stages in the development of the disease and, accordingly, treatment options.

At the first stage, the detrusor is compensatory hypertrophied, which ensures complete evacuation of urine.

There have not yet been noted violations of the kidneys or upper urinary tract, however, signs of dysuria already appear in the form of changes in the frequency and duration of urination.

How many times does a grown man need to go to the toilet? Experts believe that the total average volume of urine excreted per day is about 1.5-2 liters, and the normal bladder capacity is 0.25-0.3 liters. Therefore, a healthy person should give about 4-5 mictions per day. Otherwise, dysuric disorders are observed, for the correction of which “Omnik” tablets are prescribed.

At the 2nd stage of the development of prostate adenoma, the detrusor already undergoes dystrophic changes, which gives insufficient contractility and, as a result, the appearance of residual urine - from 0.1 to 1.0 l.

This stage is accompanied by a change in the transport of urine in the kidneys and ureters, which leads to compensated renal failure.

Dysuria persists, there are more frequent urges to go to the toilet, accompanied by pain.

It is better to start taking drugs for the treatment of adenoma without bringing the disease to the 3rd stage, at which the detrusor acquires decompensation functions, the upper urinary tract is dilated, the renal pelvis and calyx are enlarged, renal failure increases. Urine is retained chronically, involuntarily excreted at night, then in the daytime (paradoxical ischuria, based on the urine overcoming the cystic sphincter).

When treating hyperplasia, Omnik tablets are often combined with drugs that correct the state of the body that led to adenoma.

These can be hormonal disorders at the level of the gland itself or in the region of the pituitary-hypothalamus ligament.

The ratio of sex hormones (estrogens-androgens, prolactin, luteinizing and follicle-stimulating hormones) is also of great importance for the proper functioning of the prostate gland.

Hyperplasia may have as a prerequisite a violation of the synergistic action of androgens with estrogens, which gives distortion of enzyme reactions and a corresponding effect on some DNA strands that trigger cell growth prostate gland.

The main indication for the appointment of the drug "Omnik" are various dysuric disorders associated with benign hyperplasia. The main active ingredient of the tablet is tamsulosin.

This substance has the ability to reduce the increased tone of smooth muscles in the prostatic urethra, in the neck of the bladder, in the prostate itself, which gives a good outflow of urine, reduces urinary irritation channels.

Omnik is almost completely absorbed in the gastrointestinal tract (90%), excreted mainly by the kidneys (up to 10% unchanged), partly with feces.

In addition to the active substance, tamsulosin hydrochloride, the drug contains the following additional substances:

1. Iron oxides (red and yellow).
2. Talc.
3. Indigotin.
4. Gelatin.
5. Titanium dioxide.
6. Polysorbate 80 and MCC.
7. Methacrylic acid as a type C copolymer.
8. Sodium lauryl sulfate.
9. Triacetin.
10. Calcium stearate.

Omnik is available in modified-release capsules, which are not recommended to be chewed when taken, so as not to change the rate of passage of chemical reactions. It is taken in the morning after breakfast (food intake increases bioavailability). The medicine box contains 1 or 3 blisters with 10 capsules of 0.4 g each.

Unpleasant side effects from the drug

The drug containing tamsulosin can be used for treatment only after verification of the diagnosis (to exclude carcinoma) and with regular digital examination. In some cases, the determination of the prostate-specific antigen will be required. The drug should be used with caution for persons whose profession is associated with increased concentration of attention (drivers, etc.).

Reviews of Omnik capsules are very diverse, since the drug has a fairly large number of side effects.

Among them, asthenia and headache, dizziness, drowsiness or insomnia may appear on the part of the nervous system.

A number of patients note retrograde ejaculation (failure in the semen ejection mechanism) with increased sexual excitability (2-3 intercourse per hour).

Many men are wary of the disappearance of sperm during intercourse, but this is only a temporary side effect. phenomenon from taking the drug, since the ejaculate for a certain period is not released correctly, but is thrown into the urinary bubble.

There are more than enough negative reviews about the omnic. Some representatives of the stronger sex, after taking it, developed itching, shortness of breath, headaches, anxiety, after which some quit taking it without completing the course of treatment. Thus, the side effects from the work of the drug appeared (plus changes in the functioning of the prostate, which also made themselves felt).

Most likely, in such a situation, the doctor simply did not explain to the patient that negative reactions will disappear after 2-3 weeks together with the manifestation of the medicinal properties of the drug, which can be prescribed to individual patients for treatment by 2-3 months.

Contraindications to use and reception features

In addition to the effect on the genitourinary and nervous system, reviews report that omnic can give hypotension, chest and back pain, rhinitis, fainting and tachycardia. Someone taking the drug caused constipation or, conversely, diarrhea, nausea, vomiting (reaction of the gastrointestinal tract).

Sometimes treatment is accompanied by such a phenomenon as priapism (prolonged erection, not associated with sexual arousal, often painful) or, conversely, a temporary decrease in libido.

Reviews of the drug "Omnik" indicate that it should only be taken in courses on an ongoing basis, that is, every day, without gaps, so that the vascular tone does not experience stress.

Overdose gives acute hypotension, in which the patient is placed in a supine position, vasoconstrictor is administered drugs, plasma replacement solutions, wash the stomach and give an osmotic laxative or drugs like activated carbon. The drug is often prescribed not immediately, but after a course of suppositories, massage of the prostate gland, if they did not give the desired effect.

Contraindications to taking the drug are: severe hepatic failure, renal severe insufficiency, orthostatic hypotension, allergy to the main or side Components.

Source: https://kakbik.ru/andrologiya/prostata/omnik-otzyvy.html

Medicine Omnik - instructions for use, analogues of the drug, side effects, reviews of urologists, what is the difference from Omnik Okas

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Omnic is a medication to facilitate urination, which can be hampered by overgrowth and pressure of prostate tissue. The active ingredient of this drug is tamsulosin, which selectively blocks alpha-adrenergic receptors and thus relaxes the smooth muscles of the prostate gland and urinary tract.

Omnik begins to act gradually and the effectiveness of its use becomes noticeable after two weeks of admission. In this case, the phenomena of irritation of the ureters are removed. Omnik does not have a vasodilating effect and does not lower blood pressure either in patients with normal parameters or in hypertensive patients.

This drug is indicated for prostate adenoma, accompanied by impaired urine outflow.

Omnik is produced in the form of capsules and tablets Okas with prolonged, dosed release. The instruction of the drug indicates that even in the presence of concomitant violations of liver or kidney function of moderate severity, it is not required to adjust its dose.

Omnic should not be used with intolerance to its components, orthostatic hypotension. Also, severe renal and hepatic pathologies are contraindications or reasons for taking it especially carefully.

Side effects and overdose by Omnik

At the time when treatment with Omnik is carried out, the patient may experience undesirable effects of this drug. on the cardiovascular and nervous systems, for example, palpitations, drop in blood pressure, dizziness and rarely - fainting. The work of the digestive organs may be disrupted, which will result in nausea, diarrhea, and so on. Also, sometimes the reproductive system or respiratory system is exposed to the side effects of the drug, allergies can develop - up to Quincke's edema.

It is not known about cases of acute overdose by Omnik, but when an excessive dose of this drug is taken, the pressure may drop sharply and tachycardia, that is, rapid heartbeat, may develop. In these cases, it is proposed to flush the sick stomach, give activated charcoal, and provide rest. But the main thing is to seek medical help on time.

Analogues cheaper than Omnik

The active component tamsulosin, which forms the basis of Omnik, is also present in a number of products. Here is a list of them:

For the most part, these analogues of the Omnik drug are cheaper. Their cost is practically the same. For example, a package of 30 capsules of 400 mg of Proflosin, Fokusin, Sonizin, Tamsulosin will cost about 420-450 rubles.

Reviews about Omnik

Reviews about taking the drug Omnik are very different. For many, the drug helps, makes life more comfortable. But one man described that over time, Omnik began to act weaker - its effect was not enough for a day. As a result, this patient had to replace this remedy with another, more powerful one.

Another post talks about the side effect of Omnik - retrograde ejaculation. This symptom is characterized by the absence of sperm ejection at the end of intercourse - that is, it is thrown out, but not outside, but into the bladder. The development of this pathology is associated with a violation of the tone of the sphincters of the genitourinary system.

For some patients, Omnik does not bring any relief.

Obviously, prostate adenoma is a complex disease, combined with a number of symptoms and concomitant pathologies.

Therefore, it is so difficult to make general recommendations or create drugs that are suitable for all patients suffering from this disease.

Likewise, Omnik does not help someone at all, but for someone it becomes a guarantee of normal existence. And only doctors should be engaged in the selection of drugs, on the basis of the conducted research.

Overall Rating: 3.7 out of 5Please sign in to post comments Overall Rating: 3.7 out of 5

Source: http://zhivizdorovim.ru/lekarstva/drugie-lekarstva/975-omnik.html

Omnic

1 capsule of the drug Omnik contains 400 mcg tamsulosin.

Additionally: microcrystalline cellulose, triacetin, methacrylic acid copolymer (type C), lauryl sulfate sodium, polysorbate 80, calcium stearate, talc, indigodin, gelatin, titanium dioxide, iron oxide yellow and red.

Release form

Medicine Omnik is produced in the form of capsules with modified release No. 10, No. 30 or No. 100 in a package.

pharmachologic effect

Alpha adrenolytic.

Pharmacodynamics and pharmacokinetics

Tamsulosin refers to drugs from the group of specific blockers postsynaptic alpha1-adrenergic receptorspresent in smooth muscles prostate (prostate), prostatic department urethra and the neck of the male Bladder. When blocking tamsulosin alpha1-adrenergic receptors there is a decrease in muscle tone prostate, prostatic urethra and bladder, which leads to an improvement urination. In parallel with this, there is a weakening of symptoms. emptying and filling bladder with prostate adenomawhich are due detrusor hyperactivity and high muscle tone of these organs.

Impact tamsulosin on the alpha 1A-subtype adrenergic receptors 20 times its effect on adrenergic receptors alpha 1B-subtypelocated in vascular smooth muscle tissue.

Due to such a high selectivity, the reception tamsulosin does not lead to clinically significant lowering systemic blood pressure, both in relation to patients with normal blood pressure, and in relation to patients suffering from arterial hypertension, from which the drug Omnik can be prescribed for hypertensive patients.

In the intestines tamsulosin absorbed quite well and has almost 100% bioavailability. With a combined meal, the absorption process slows down slightly. An equal degree of absorption of the drug can be achieved with constant intake by the patient tamsulosin after daily breakfast.

Characteristic of tamsulosin is its linear kinetics. A single internal intake of 0.4 mg of the drug leads to its plasma Cmax after 6 hours.

With a constant daily oral intake of 0.4 mg tamsulosin its equilibrium concentration is observed already by the 5th day, at the same time it is approximately 2/3 higher than this value observed with a single dose of the drug.

Binding to plasma proteins is 99%, Vd is about 0.2 l / kg.

Hepatic metabolic transformations tamsulosin pass rather slowly, with the release of less active products metabolism. Main part tamsulosin is in blood plasma in a natural unaltered form.

Conducted research tamsulosin proved its ability to slightly induce the activity of microsomal liver enzymes.

At liver pathologies, up to a moderate degree, adjustment of the dosage regimen of Omnik is not required.

Unchanged tamsulosin, like the products of its metabolism, are mainly excreted by the kidneys. T1 / 2 of a single oral dose (0.4 mg) of the drug after meals is equal to 10 hours. With repeated administration, this figure is 13 hours.

At kidney pathologies moderate dose adjustments tamsulosin not required. In the case of severe kidney failure (CC less than 10 ml / min), there is a need for the careful appointment of Omnik.

Indications for use

Indications for use of the drug Omnik include therapy of dysuric disordersobserved at prostate adenoma.

Contraindications

• personal hypersensitivity sick to tamsulosin or other ingredients of capsules;
• heavy failure of hepatic function;
• orthostatic hypotension (including indications in history).

The careful use of Omnik is required by patients with severe kidney pathologies (CC is less than 10 ml / min).

Side effects

During therapy with the use of Omnik capsules, it was occasionally observed:

Omnik, instructions for use

Taking capsules of the Omnik medication involves taking them orally (inside) immediately after completing breakfast, drinking 100-200 ml of water. The intake of 400 mcg of the drug (1 capsule) is shown per day. Instructions for use Omnik does not allow chewing capsules, as this can lead to an increase in the rate of release of the active ingredient from them.

Overdose

Evidence of acute overdose when taken tamsulosin does not exist. Theoretically, when taking excessive dosages of this drug, there can be a rapid decrease in blood pressure and development compensatory tachycardiarequiring symptomatic treatment.

The patient's heart rate and blood pressure can return to normal when he takes a horizontal position. If this method is ineffective, it is possible to use drugs that increase the volume bloodcirculating in the vascular bed. If necessary, appoint vasoconstrictor medications.

Against the background of the treatment, it is necessary to monitor renal function. Efficiency hemodialysis due to significant binding tamsulosin with plasma proteins is questioned.

It will also be advisable to cleanse the gastrointestinal tract (laxative, washing) and reception sorbents.

Interaction

Combined administration of tamsulosin with Atenolol, Nifedipine or Enalapril did not lead to any interaction of these drugs.

When used in parallel Cimetidine observed a slight increase in plasma concentration tamsulosin, and when applying Furosemide - a decrease in this indicator. This combination of drugs does not require a change in the dosage regimen of Omnik, since the content of its active ingredient in the plasma remains within the therapeutic norm.

Warfarin, Propranolol, Diazepam, Trichloromethiazide, Amitriptyline, Chlormadinon, Diclofenac, Simvastatin and Glibenclamide in vitro do not affect the free fraction in plasma tamsulosinwhich, in turn, does not violate free factions Chlormadinona, Propranolol, Diazepam and Trichloromethiazide.

Also in vitro, at the level of metabolism in the liver, no interaction of the active ingredient Omnik with Amitriptyline, Glibenclamide, Salbutamol and Finasteride.

Simultaneous reception Warfarin and Diclofenac may increase the rate of excretion tamsulosin.

With joint therapy with other antagonists of alpha 1-adrenergic receptors, a decrease in blood pressure is possible.

Terms of sale

The purchase of Omnik requires the presentation of a prescription.

Storage conditions

The temperature indicators for storing capsules should be within 15-25 ° C.

Shelf life

From the moment of capsule production - 4 years.

special instructions

During therapy with the drug Omnik, it was occasionally observed lowering blood pressure the patient receiving it, which can cause fainting.

If the first signs of formation are detected orthostatic hypotension (feeling weaknesses, dizziness) the patient is recommended to take a sitting or horizontal position, until the negative signs completely disappear.

Surgical interventions on the organs of vision for cataracts at the reception tamsulosin can lead to the onset of the syndrome intraoperative instability of the ocular iriswhat must be remembered by the surgical staff for the correct preoperative preparation of the patient.

Before starting treatment using Omnic, the patient must undergo an examination in order to exclude pathologies with symptoms identical to the manifestations prostate adenoma.

Before the appointment of therapy, and regularly throughout its duration, the patient should be rectal digital examination and, if necessary, determine the presence of a specific prostatic antigen.

Omnik's analogs

The price of Omnik analogs varies over a fairly wide range and depends on many factors (active ingredient and its mass content, number of tablets / capsules, manufacturer, etc.). For example, 30 tablets Uroreka can be bought for an average of 750 rubles, while purchasing 30 tablets Dalphase will cost 2,200 rubles.

Avodart and Omnik

Although these two medicinal preparations are analogous in their pharmacological affiliation, but include in their composition various active ingredients that affect different pathological processes, inherent adenoma.

The drug Omnik is rather a symptomatic remedy designed to get rid of dysuric disorders (normalizes urination) by relaxing the muscles of the prostate.

Medicine Avodarton the contrary, designed to reduce the size of the tumors, by reducing the concentration dihydrotestosterone, contributing to its growth.

Both of these medications are often used in combinatorial therapy, where they complement each other's effects.

Synonyms

Omnik and Omnik Okas

These drugs are 100% synonyms, that is, they include the same active ingredient (tamsulosin) in an identical mass fraction (400 μg). Naturally, patients with prostate adenoma often ask themselves what is the difference between Omnik and Omnik Okas.

The difference between these drugs lies in their dosage form, capsules for the first and tablets for the second, and Omnik Okas tablets are characterized by controlled release, in other words, have a more constant concentration of their active ingredient observed in the body throughout the day.

This quality of tablets allows tamsulosin with equal force to influence musculature of the prostate within 24 hours, and also, due to the absence of changes in the concentration of the active ingredient, less often leads to the development of negative side effects, from which Omnik Okas tablets are considered more effective and safe.

Which is better - Omnik or Fokusin?

Fokusin as well as the previous preparation, it is 100% synonymous with Omnic in terms of the active ingredient, its mass content and release form (capsule).

The manufacturers of both drugs have approximately equal credit of trust among doctors and patients, which indicates a complete interchangeability of these medicines.

When choosing between these drugs, you should proceed from their availability in pharmacies in your city and the cost (price Fokusina in Russia about a third lower).

For children

Due to the formation prostate adenoma, mainly in adulthood, the appointment of Omnik to children is not practiced.

During pregnancy (and lactation)

The drug is intended exclusively for the treatment of male patients.

Reviews about Omnik

In 70% of cases, doctors' reviews, as well as patient reviews about the effectiveness of Omnik, when used strictly according to indications, are positive.

Many urologists prescribe this medication for prostatitis, prostate adenoma and with other painful conditions that occur with problems urination, where the relaxing effect of tamsulosin on the muscles prostate really helps to get rid of the negative symptoms of the disease.

In fairness, it is worth noting some negative reviews about Omnic on the forums discussing its side effects, the most significant of which are development hypotension and retrograde ejaculation.

It must also be remembered that during therapy prostate adenoma the appointment of Omnik is symptomatic, aimed at getting rid of dysuric disorders, and a full-fledged treatment of this disease requires an integrated approach, with the use of drugs of various groups, indicated for such pathologies.

Omnik price where to buy

The average price of Omnik # 10 is 350 rubles; No. 30 - 750 rubles. You can buy 100 capsules of this drug for 2200-2500 rubles.

• Online pharmacies in Russia
• Online pharmacies of Ukraine
• Online pharmacies of KazakhstanKazakhstan

WER.RU

• Omnik Okas tablets 0.4 mg 10 pcs. Astellas Pharma Inc. [Astellas Pharma]
• Omnic capsules 0.4 mg 10 pcs. Astellas Pharma Inc. [Astellas Pharma]
• Omnic capsules 0.4 mg 100 pcs. Astellas Pharma Inc. [Astellas Pharma]
• Omnik Okas tablets 0.4 mg 30 pcs. Astellas Pharma Inc. [Astellas Pharma]

Zdravzona

• Omnik Okas 0.4mg No. 30 controlled release tablets Astellas Pharma Europe B.V.
• Omnic 0,4mg No. 10 capsules with modified release Astellas Pharma Europe B.V.
• Omnic 0,4mg No. 30 capsules with modified release Astellas Pharma Europe B.V.
• Omnik Okas 0.4mg No. 10 controlled release tablets Astellas Pharma Europe B.V.
• Omnic 0,4mg No. 100 capsules with modified release Astellas Pharma Europe B.V.

Pharmacy IFK

• Omnik Okas Astellas Pharma Europe B.V./Ortat CJSC, Russia
• Omnik Astellas Pharma Europe B.V./Ortat CJSC, Russia
• OmnikZdorovye ZAO, Russia
• Omnik Astellas Pharma Europe B.V./Ortat CJSC, Russia
• Omnik Okas Astellas Pharma Europe B.V./Ortat CJSC, Russia

Pharmacy24

• OmnicYamanouchi Europe (Netherlands)
• Omnic Astellas Pharma Europe (Netherlands)
• Omnik Okas Controlled Release Tablets 0.4mg No. 30 Astellas Pharma Yurop BV Leiderdorp (Netherlands)

PaniApteka

• Omnic caps. 0.4mg No. 30Astellas Pharma Europe B.V. Leiderdorp
• Omnic caps. 0.4mg No. 30Astellas Pharma Europe B.V. Leiderdorp
• Omnic caps. 0.4mg No. 30Astellas Pharma Europe B.V. Leiderdorp

BIOSPHERE

• Omnic 0.4 mg No. 30 capsules with modified release. Astellas Pharma Europe B.V. (Netherlands)
• Omnik Okas 0.4 mg No. 30 tabl.p. Astellas Pharma Europe B.V. (Netherlands)

NOTE! Information about medicines on the site is a general reference, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medicines in the course of treatment.

Before using the drug Omnik, be sure to consult with your doctor.

Source: https://medside.ru/omnik

The action of the drug Omnik in benign prostatic hyperplasia

In the treatment of prostate adenoma, the drug Omnik is used. The drug helps to eliminate the clinical picture of benign prostatic hyperplasia. The medicine relieves pain, irritation and inflammation in soft tissues. The therapeutic effect relieves obstruction and normalizes the activity of the urethra.

1 International non-proprietary name

Tamsulosin

In the treatment of prostate adenoma, the drug Omnik is used.

Trade name

Tamsulozin, Omnik

Registration number

LS-000849-140817

ATX

G04CA02

2Composition and dosage forms

The drug is available in only one dosage form - capsules. The units of the medication are covered with an orange gelatinous shell. The body of the preparation is painted in 2 colors.

One half is bright orange (marked with the manufacturer's trademark and number 701), the other is dark green with 0.4 engraving.

The contents of the capsules are visually white with a yellowish tinge porous granules.

The drug unit contains 400 μg of the active ingredient - tamsulosin hydrochloride. The following are used as auxiliary components in production:

• microcrystalline cellulose;
• calcium stearate;
• ethyl acrylate and methacrylic acid copolymer;
• triacetin;
• sodium lauryl sulfate;
• talc.

The adrenolytic effect of the drug leads to a decrease in the tone of the urinary tract.

The hard shell consists of gelatin, titanium dioxide, indigo carmine. The orange color of the capsules is given by yellow and red dyes based on iron oxide. The drug is contained in contour cell packs of 10 pieces. The carton contains 1, 3 or 10 blisters.

3 Pharmacological group

The drug belongs to the group of inhibitors of alpha-adrenergic receptors and is included in the class of drugs used in diseases of the prostate gland.

4 Pharmacological action

The adrenolytic effect is due to the blocking of alpha1-adrenergic receptors by tamsulosin, which leads to a decrease in the tone of smooth muscles of the prostate, bladder neck and urinary tract.

As a result, the outflow of urine improves, the symptoms of urine release and accumulation decrease, which are observed only when the smooth muscles of the urinary system organs are stressed.

The situation can be complicated by involuntary contractions of the detrusor (muscles of the bladder) in the benign form of prostatic hyperplasia.

Tamsulosin acts on beta1-adrenergic receptors located in the vascular walls, 20 times weaker than on alpha1-adrenergic receptors localized in muscles. This selectivity (selectivity) allows you to avoid a decrease in blood pressure against the background of arterial hypertension or hypotension at normal blood pressure (arterial pressure).

When taken orally, tamsulosin begins to be rapidly absorbed in the small intestine by 100%.

When taken orally, tamsulosin begins to be rapidly absorbed in the small intestine by 100%. Food intake slows down the absorption of the active compound. After receiving a single dosage, the active substance reaches its maximum values ​​in blood plasma after 6 hours. With repeated administration, the equilibrium plasma concentration is observed on the 5th day of drug therapy.

When a chemical compound enters the bloodstream, a 99% connection with plasma proteins is observed. Thanks to this complex, the drug is quickly distributed throughout the tissues.

The active compound and metabolic products leave the body with urine. In this case, 9% of the drug is excreted in its original form. The half-life after a meal reaches 10 hours with a single application, and 13 hours with repeated use.

5Indications for the use of Omnik

The drug is intended for the treatment and prophylaxis of violations of the urinary function against the background of benign hyperplasia (adenoma) of the prostate gland. In clinical practice, it is used for pathological narrowing of the urethra in women.

6 Benefits and harms of the drug Omnik

The medication helps at various stages of benign prostate adenoma and avoids surgery. Moreover, the drug has additional advantages:

1. When taking the medicine, the urination process is normalized.
2. As a result of achieving a therapeutic effect, there is no negative effect on potency. The drug acts safely on soft tissues.
3. The drug has no direct effect on blood pressure, which allows people with hypertension to take the drug.
4. With a decrease in the tone of smooth muscles, the metabolism in the prostatic part of the urethra is normalized.

It should be remembered that taking medications is an artificial interference in the activity of the body. When taking the medication, allergic reactions or side effects may develop. The drug must be taken for medical reasons.

7 Method of administration and dosage

The drug is used for oral administration by mouth. The standard treatment regimen is 1 capsule with a dose of 0.4 mg per day. In this case, the drug should not be chewed or crushed, because the hard gelatin packaging is designed to reduce the rate of release of chemicals.

How long to take

The duration of treatment to maintain the therapeutic effect is determined on an individual basis by a medical specialist. The severity of the disease and the nature of the pathological process play a key role in determining the duration of therapy.

It is recommended to take the capsules after breakfast.

In most cases, capsules are taken for 1-2 months, 2 times a year as a preventive measure or when a symptomatic picture of prostate adenoma appears. The therapeutic effect occurs within 2 weeks from the start of treatment. If relief does not come within 14 days, you need to consult with your doctor about changing the drug or adjusting the daily dose.

Before or after meals

It is recommended to take the capsules after breakfast. You need to drink the drug with plenty of water.

8 Special instructions for Omnik

In special cases, during treatment with Omnik, a strong decrease in blood pressure is possible, as a result of which loss of consciousness occurs. At the first signs of a fall in blood pressure - dizziness and weakness in the skeletal muscles, it is necessary to take a sitting or horizontal position. In this position, it is necessary to remain until the signs of hypertension completely disappear.

During the rehabilitation period or during a cataract surgery, instability of the iris of the eye (disease of the narrow pupil) may occur. Before the operation, it is necessary to inform the surgeon about taking Omnik in order to avoid unpleasant consequences.

In special cases, during treatment with Omnik, a strong decrease in blood pressure is possible, as a result of which loss of consciousness occurs.

Before prescribing the drug, it is necessary to examine the patient for the presence of other diseases that can recreate the clinical picture of benign prostate adenoma. An accurate diagnosis is required.

Before starting and during the period of drug therapy, it is necessary to regularly palpate the rectal passage.

For violations of liver function

The drug is metabolized in hepatocytes, which is why in case of incorrect liver function, care must be taken when taking it.

With impaired renal function

The drug does not affect the activity of the kidneys, therefore, in case of renal failure, no additional dose adjustment is required.

9 Side effects

Organs and systems from which the violation occurred	Negative reactions
The cardiovascular system	orthostatic hypotension; tachycardia; sensation of blood flow in the temples.
Central and peripheral nervous system	dizziness; headache; general weakness.
Reproductive system	Retrograde ejaculation, in which there is a violation of ejaculation. As a result of inflammation, semen enters the bladder and mixes with urine.

10 Contraindications

The only contraindication to taking the drug is tissue hypersensitivity to structural components.

11 Overdose

In the course of clinical practice, there were no cases of manifestation of symptoms of an overdose with the abuse of Omnik. Hypothetically, acute hypotension (drop in blood pressure) and a compensatory increase in heart rate are possible.

With a decrease in pressure in the blood vessels, it is necessary to transfer the victim to a horizontal position and raise his legs in order to normalize blood pressure. There is no specific antidote, therefore, treatment when the condition worsens while taking a high dose is aimed at eliminating the symptoms of an overdose.

If the drug is taken within 4 hours, gastric lavage should be performed.

If the drug is taken within 4 hours, it is necessary to wash the stomach, give an adsorbent and induce vomiting. In the absence of a patient's response, it is required to enter funds that increase the volume of circulating blood. If necessary, take vasoconstrictor medications. In the process of symptomatic treatment, renal function must be monitored. Hemodialysis is ineffective.

12 Drug interactions and compatibility

With the simultaneous use of Omnik with other medications, the following reactions are observed:

1. Cimetidine increases the plasma concentration of tamsulosin, while furosemide reduces the level of the active substance in the blood. At the same time, no dose adjustment of the drugs is required - the changes are insignificant, the concentration of the compounds remains within the normal range.
2. In combination with alpha1-blockers, a sharp drop in blood pressure is possible.
3. Diazepam and Diclofenac do not affect the therapeutic effect of the drug. Tamsulosin does not alter the concentration of Chlormadinone and Propranolol.
4. Diclofenac and Warfarin are able to reduce the half-life of tamsulosin, which increases the excretion of the latter.

With alcohol

When ethanol enters the bloodstream, the vasodilating effect is enhanced, which leads to a sharp drop in blood pressure to a critical minimum. The person loses consciousness. When taking a large amount of alcohol, a coma and death may occur.

Diclofenac and Warfarin are able to reduce the half-life of tamsulosin.

With the simultaneous neutralization of tamsulosin and ethyl alcohol, the liver cells are exposed to high stress. Under such conditions, hepatocytes do not have time to deactivate toxic compounds, and massive cell death begins. The necrotic areas are replaced by connective tissue, which leads to fatty degeneration of the liver.

Negative consequences are dangerous for the normal functioning of organs, therefore, during the period of drug therapy, it is necessary to refrain from drinking alcoholic beverages.

13 Conditions of dispensing from pharmacies

The drug is sold only with a doctor's prescription.

Manufacturer

Astellas, Netherlands.

Price

The average cost of 10 Omnik tablets reaches 388 rubles, 30 - 860 rubles, the price for 100 pcs. is 2325 rubles.

14 Conditions and shelf life

It is recommended to keep the preparation in a dry place, away from sunlight, at temperatures up to +25 ° C. Shelf life is 4 years.

Before replacing the Omnik, you should consult with your doctor.

15Analogues

On the pharmacological market there are analogs, the mechanism of action of which is based on tamsulosin. The only difference is pharmacokinetics. These drugs include:

• Tamsol;
• Tamsulosin;
• Omnik Okas;
• Urorek;
• Fokusin;
• Proflosin.

Drugs with a similar mechanism of action are represented by Prostamol, Dalfaz, Afirum. It is important to remember that it is not recommended to switch to another medication on your own. Before replacing the Omnik, you should consult with your doctor.

16Reviews by men

Igor Barinov, 35 years old, Yekaterinburg

Prescribed a drug for taking 1 capsule per day. After the first intake, my erection fell by 70%, I woke up from feeling unwell. I tried to drink, but then ejaculation disappeared, dizziness began. And all this in 4 days of therapy. Urination improves, but it did not suit my body.

Alexander Tverdolobov, 43 years old, Rostov-on-Don

Omnik capsules were prescribed after an ultrasound of the prostate gland, on which an adenoma was found. Drank during the year 2 times for one month. Improvements were observed after the first dose, because immediately felt relief when urinating.

But there is only one strong drawback - the drug dilates blood vessels. I have chronic rhinitis and within 2 hours after taking it, my nose gets stuffy to such an extent that I stop breathing. You have to drip vasoconstrictor.

Urination has returned to normal, so I recommend it to those who do not suffer from hypotension and runny nose.

17Reviews of doctors

Yuri Kaptsov, urologist, 54 years old, Arkhangelsk

Omnik capsules have established themselves as an original drug for improving the condition of benign prostatic hyperplasia. Has a prolonged effect.

The tool has a quick and lasting therapeutic effect, thanks to which the medication can be used several times a year, and not on an ongoing basis.

At the same time, the drug had drawbacks in my clinical practice - patients complained of backward ejaculation, dizziness and a drop in pressure.

Anton Mukhtyarov, urologist, 38 years old, Krasnoyarsk

A common drug for the treatment of prostate adenoma. Has a minimum of side effects. You can buy 10 capsules cheaply from pharmacies.

Vasily Lange, urologist, 43 years old, Vladivostok

The original, high-quality drug has repeatedly saved from surgery for prostate adenoma. I am seeing a pleasant drop in prices for 30 capsules, which has made the drug more affordable. Well tolerated for a long course.

Source: https://prostatis.ru/omnik.html