Adenosine: indications for use, instructions, influence on immunity

By its chemical composition, this compound is a nucleotide. Adenosine is needed for the transmission of nerve impulses and signals, for the production of cellular energy. A substance is important and necessary for the functioning of the body, it is present in all cells, protecting them from the effects of unfavorable factors. Refers to biologically active compounds. If the cell is inflamed or damaged, then its amount rises sharply.

How to apply the drug correctly?

The drug has an antiarrhythmic effect, improves cerebral and coronary circulation, increases the rate of peripheral circulation. If a person has problems with the cardiovascular or nervous system, then, probably, in specific cases, this drug will be assigned to him. Let's consider its action in more detail. So, Adenosine: Instructions for use:

1. When arrhythmias in adults Adenosine is administered intravenously, quickly( for 1-2 sec).The dosage used is 6 mg. If the improvement does not occur approximately after 1-2 minutes, then a double dose is administered, it is also considered the maximum( should not exceed 12 mg).If necessary, the injections are repeated at regular intervals.
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2. At the risk of complications, treatment begins with minimal doses, which increase gradually, based on the disease.

Children are also given medication intravenously, bolus( rapid infusion).The dose is calculated based on the weight of the child. For each kilogram of weight, 50 mg of substance is taken. The dose should not exceed 250 mg per kg of body weight. Repeated injections are performed as needed every 2 minutes.

Recommendation! If adenosine is used for diagnostic purposes, then the administration of either intravenous or intraosseous amounts of 6 mg. The injection is made as close as possible to the heart. After 1-2 minutes, if such a need arises, an additional dose is administered.

Ophthalmology also uses Adenosine, the instructions for use of which will differ:

1. Slows down the negative changes that can occur in the lens( processes of degeneration: destruction).It is excreted through the kidneys in the form of metabolites.
2. Use local: the substance penetrates well through the cornea of ​​the eye and is evenly distributed throughout the tissues of the eye. Form release - 1% solution for injection or eye drops.
3. The action of the drug is a vasodilator, therefore the blood supply to the eye is improved. Relieves inflammation in various tissues of the eye.

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Side effects of

Based on the instructions for use of Adenosine, there may be side effects. They can be of two types. The first occurs with rapid intravenous administration:

1. Influence on the nervous system: headache, nervousness, vision problems.
2. Cardiovascular system: low blood pressure, blood flow to the mouth. In the chest area, a feeling of pain, sometimes there may be new arrhythmias, tachycardia, a change in the pulse rate.
3. Breathing: the occurrence of dyspnoea and chest pressure.
4. GASTROINTESTINAL TRACT: feeling of nausea, metallic taste in the mouth.
5. Sweating profusely.

The second type of side effects is possible with a slow introduction:

1. Body condition: weakness, discomfort in the back or lower extremities.
2. Heart and blood vessels: increased sweating, severe palpitation, possible myocardial infarction without lethal outcome, lowering blood pressure.
3. Nervous system: constant desire to sleep, loss of vision, trembling in the whole body.
4. Respiratory: Possible strongly pronounced cough.

In the instructions for the use of Adenosine, it is said that such side effects are rare. The probability of their occurrence is 1%.Perhaps they will not be at all. If any signs still appear, you need to contact the attending physician to correct the treatment. With other drugs, he interacts in different ways: weakens or intensifies their action. This is worth considering when treating.

Analogues of

Like most other drugs, Adenosine has analogues. They have a similar effect, but not 100%.In addition, similar substances can have the opposite effect on different people. Do not change the drug without consulting a doctor. So you can get additional side effects and hurt yourself.

The most common analogues of Adenosine:

• Adenocorus;
• Vitakik;
• ATP;
• Romekor.

The cost of adenosine is relatively low and is 250 rubles per pack.

Contraindications

The instructions say that Adenosine has contraindications. The drug categorically can not be used in case of hypersensitivity, bronchial asthma, weakness syndrome of the sinus node. Its use is possible, but with special care, in the following cases: heart defects, hypovolemia( decrease in the volume of blood circulating in the human body), unstable angina, sinus bradycardia( low heart rate).

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Overdose

In case of an overdose, the substance is quickly removed from the bloodstream. All reactions proceed with great speed and no consequences arise. You can use antagonists of this drug. After you need to carefully examine the ECG.Of course, both an overdose and adenosine intake affect immunity. Immunity suffers from taking any medications.

Intravenous administration is important in a hospital setting under the supervision of physicians. To the effect of the drug was effective, and the dose was consistent with the instructions. It is worthwhile to draw the attention of people with diabetes to the fact that stopping adenosine intake improves the absorption of insulin.

The drug is universal, and its effects are many good reviews, so it is used in a variety of ways. But in any case, do not self-medicate, act only under the supervision of a doctor.