Features of the use of Acetylsalicylic acid

Acetylsalicylic acid belongs to the group of non-steroidal anti-inflammatory drugs. This medicine and its analogs are one of the most popular drugs. It has anti-inflammatory, and therefore antipyretic, and also analgesic effect. In addition, this drug is considered one of the most affordable drugs for the price category. Does Acetylsalicylic Acid Help with Headache? This non-steroid drug reduces any pain, but acetylsalicylic acid is more effective against headaches, and for any reason.

The mechanism of analgesia of acetylsalicylic acid

The analgesic effect of Acetylsalicylic acid is as follows:

1. The inflammation is suppressed by inhibiting the synthesis and action of inflammatory mediators, including their effect on pain receptors.
2. This drug has a retarding effect on the center of pain sensitivity. As a result, the pain decreases.
3. Pain in any part of the body, and the headache in particular, may be the cause of insufficient blood supply to a particular organ or part of it as a result of spasm of blood vessels, overlapping of small vessels with thrombi. Acetylsalicylic acid reduces platelet aggregation of blood, which rises in any inflammatory process, "dilutes it."Possessing spasmolytic activity, it stops the spasm of the vessels, expanding their lumen. Due to these properties, the drug improves the blood supply to the structures of the brain and other organs.
4. Reducing the phenomenon of vasospasm, Acetylsalicylic acid reduces the level of intracranial pressure, which also contributes to reducing head pain.

Therefore, Acetylsalicylic Acid from the head is relevant in that it will reduce pain not only by stopping the inflammatory response, affecting pain receptors. She removes it, improving the blood supply of the affected area.

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Admission Features

The maximum dose for a single adult should not be more than 2 tablets. In the event that a person has the opportunity to lie down with a headache, rest, then you can confine to taking one tablet.

It is believed that Aspirin is more effective for taking with a headache immediately, when it occurs. Children are prescribed by sex tablets( 250 mg).In a day you can take 3 tablets. Take the drug after eating. They wash it with water in large quantities. As an analgesic, you should not take it longer than a week.

Contraindications

The drug is not used in the following conditions:

• in pregnant women of the first semester;
• up to 12 years;
• ulcerous changes in the gastric mucosa and 12-colon;
• for any bleeding, especially from the digestive tract;
• portal hypertension;
• hypersensitivity to salicylates;
• deficiency of vitamin K.

Adverse events

Adverse manifestations are as follows:

• abdominal pain;
• nausea, vomiting;
• diarrhea;
• allergic manifestations;
• bleeding.

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Features of Acetylsalicylic Acid in Children

Children with caution are prescribed Acetylsalicylic acid for pain of different etiology of moderate intensity. Avoid her appointment is recommended to those under 12 years of age. Today, there is a sufficient choice of pain killers and antipyretics. Therefore, for children Acetylsalicylic acid with headache can be replaced with Paracetamol, Ibuprofen. Unfortunately, these drugs also have side effects, but they occur sporadically.

Reye syndrome

This pathology is defined in some children who took Aspirin( Acetylsalicylic acid) for diseases of the respiratory tract of a viral nature. Reye's syndrome is a high probability of lethality without timely treatment.

Fact! For the first time this pathology was described in 1963 as a syndrome of encephalopathy not of an inflammatory form associated with fatty degeneration of organs in children. The edema of the brain was diagnosed, but there was no inflammation. Diseases of this pathology children on the eve of taking as an anti-inflammatory and antipyretic agents drugs group of salicylates, which includes Acetylsalicylic acid.

The exact relationship between the disease and the administration of this drug is not clear until the end. Long-term syndrome associated with viral nature. In addition to encephalopathy, children had fatty degeneration of liver cells, an increase in the level of transaminases several times, impaired renal function, an increase in the urea index. Changes at the cellular level consist in the disturbance of the functioning of mitochondria of cells in different organs.

When the connection between Ray's syndrome and the intake of Acetylsalicylic Acid was discovered, the number of prescriptions in European countries was reduced. After that, the number of cases of diseases decreased. The risk of developing this condition in the child is very small. However, given its heavy current is highly undesirable. Manifestations of Ray's syndrome are not specific. They were often taken for intestinal infection or intestinal flu form:

1. Increased respiration rate.
2. Reducing blood glucose. It happens in a short time. The younger the child, the more difficult is the lack of glucose. In infants, unlike adults, the glycogen reserve, from which glucose deficiency is compensated if necessary, is too small. Therefore, the lack of it is difficult to tolerate.
3. Pronounced lethargy, apathy.
4. Accumulation of ammonia in the blood.
5. Nausea and vomiting for no apparent reason.
6. Convulsions.
7. Impaired consciousness.
8. Aggression, not logical deeds.
9. Paralyzes of separate groups of muscles of the extremities.

It's difficult to diagnose it. Laboratory and instrumental studies are conducted. An important clue is information about ARVI the day before and about taking Acetylsalicylic acid. Check the level of liver enzymes, blood coagulation, bilirubin, amylase, lipase, glucose. An electroencephalogram is performed, CT of the brain, intracranial pressure is determined.

Important! When is suspected of this pathology, hospitalization is urgently carried out. Treatment at home is unacceptable. In the absence of treatment, deterioration of the condition is possible up to a lethal outcome.

Treatment consists in monitoring and maintenance at the vital level of the functioning of the body, symptomatic therapy( correction of glucose levels, reduction of ammonia from the blood, cramping of convulsions, vomiting).This drug can be taken from a headache, but taking into account age, contraindications and individual medical recommendations.