Akinozoospermia - causes, symptoms, treatment methods and the likelihood of conception
Akinozoospermia is a pathology in which spermatozoa lose their motor capacity.Disease is one of the main causes of male infertility.With akinozoospermia, spermatozoa can not reach the ovum and fertilize it.This is a fairly severe pathology that is difficult to treat.Table of contents: Characteristics of pathology Causes of occurrence of akinozoosperia Symptoms and signs of disease Diagnosis of akinozoospermia Methods of treatment of akinozoospermia Will children with akinosoospermia
Characteristics of the pathology of
Normally, spermatozoa develop a speed of up to 1.5 cm per minute, moving along the female genital tract.The thorn on the front helps the sperm penetrate the egg shell.It is at this moment that fertilization takes place.
With akinozoospermia, spermatozoa are practically immobile, which leads to problems with conception.
Sperm motility is determined by examining semen under a microscope and four main categories are identified:
- A: moving sperm moving in a straight line.In the absence of pathology, their number is 30%.
- In: sedentary spermatozoa moving in a straight line.The norm is considered if their content in the ejaculate is 25-30%.
- With : the spermatozoa move non-rectilinearly.The norm is no more than 25%.
- D : completely immobile sperm.Normally their number should not exceed 15%.
Please note! Reducing the number of mobile spermatozoa of category A and B to 10% is considered critical.
Depending on the species and degree of motility of the spermatozoa, the disease is divided into several types:
- The number of immobile spermatozoa is much higher than that of the moving ones.
- Sperm are mobile, but the speed of translational movements is significantly reduced.
- Spermatozoa move only pendulum-like.
- Complete absence of motile spermatozoa.
Causes of the onset of akinozoosphere
Pathology can be congenital and acquired.Congenital akinosoospermia can develop due to a genetic malfunction, or be inherited.
To the most likely reasons for the development of acquired pathology, the following factors can be attributed:
- clumping of spermatozoa among themselves;
- inflammation in the male genital organs, especially if they affect the testicles and the prostate;
- infections that are sexually transmitted;
- connection of spermatozoa to other cells;
- bad habits( smoking, alcohol, drugs);
- injuries of the testicles, which can cause autoimmune damage in which the own destruction of the reproductive cells occurs;
- the effect of radiation and certain drugs;
- autoimmune pathologies;
- violation of the ejaculate environment;
- decrease in the amount of testosterone;
- diabetes mellitus.
Important! Akinozoospermia can develop at any age in men, even in those who already have the offspring of .
Symptoms and signs of the disease
Unfortunately, akinozoospermia is asymptomatic.Immobility of sperm does not affect the quality of the intimate life of a man.Libido does not decrease, and in some cases even increases.
Often pathology is detected during examination with concomitant disease.Basically, a man can guess about the problem if for a long time in a married couple there is no conception.
Diagnosis of akinozoospermia
Pathology in men is diagnosed during a multistage semen analysis( spermogram).It is assumed a triple fence of ejaculate, with interruptions between each analysis in two weeks.
For accurate results, the following rules are recommended before passing the tests:
- for three days before the test is given to give up sexual intercourse;
- to quit smoking at least 24 hours a day;
- refrain from drinking alcohol.
In addition to the spermogram, the doctor may prescribe additional tests:
- blood tests for assessing the hormonal balance and the presence of infection;
- Prostate examination;
- scrotal ultrasound.
Based on the number of mobile spermatozoa, the pathology is divided into two types:
- Total, in which all the spermatozoa in the ejaculate are dead.
- Partial, in which among inferior spermatozoa are also present.
Important! During the diagnosis, the doctor not only diagnoses, but also determines the factors that have caused the disease.
Based on the survey, a specialist prescribes treatment and predicts the likelihood of conception.
Methods of treatment of akinosoospermia
Treatment of pathology is possible only in the initial stages. The use of agents that affect the motility of spermatozoa and improve the quality of seminal fluid. These include drugs with a high content of folic acid, L-carnitine, vitamin E and zinc.One of these drugs is Sperhoton.Clinical studies have shown that when it is taken, the number and mobility of spermatozoa with direct translational motion increases.The course of treatment is two to three months.During this time, sperm are formed.
A 5% glucose solution is also used in combination with horse serum and magnesium chloride.This means restores sperm activity.Efficacy is increased if a mixture is used in a complex of drugs to strengthen immunity.
Will children with an akinozoospermia
Conception in pathology possible if treatment is started in the early stages of development.Unfortunately, in advanced cases the probability of conception is zero.
Pair for conception is recommended to conduct ICSI + IVF procedure.With ICSI, they take seminal fluid, clean it and the doctor selects the most active and qualitative spermatozoa.
With total akinozoospermia, conception is impossible even with ICSI and IVF.In this case, the couple is offered conception by donor sperm.
Radevich Igor Tadeushevich, a doctor and sexologist andrologist of the Center for Family Planning