Preparations for the treatment of intestinal dysbiosis

Preparations for the treatment of intestinal dysbiosis are a large group, the effect of which is aimed atReplenishment of the level of natural microflora and oppression of pathogenic. Probably everyone at least once in their lives suffered from digestive problems and intestinal dysbiosis faced, so to know how is the treatment of this condition , and what preparations you can restore the normal microbial balance, will be useful for many.

Dysbacteriosis does not arise spontaneously - it may be preceded by prolonged use of antibiotics, prolonged stress, dieting and eating disorders, intestinal infections or diseases of the digestive tract. All this leads to the fact that a useful microflora is dying, and the number of conditionally pathogenic microorganisms increases dramatically.

Treatment of dysbacteriosis

In the event of imbalance between obligate and pathogenic gastrointestinal microflora, the diagnosis results in a diagnosis of "dysbiosis".Its symptoms are different and can be expressed by constipation or diarrhea, flatulence, abdominal pain. Sometimes there are diarrheal disorders, and sometimes allergic manifestations.

Therapy and choice of group of drugs for intestinal dysbacteriosis depend on the severity of the disorders.

The treatment is as follows:

1. First and foremost, you should establish the cause that triggered the digestive disorder. Reception of antibiotics, inaccuracies in the diet, inflammatory diseases of the stomach, as well as pathologies from the gallbladder and biliary tract - all this leads to a violation of microflora. Therefore, the main pathogenetic treatment should be aimed at eliminating the primary source of dysbacteriosis.
2. Coping of acute signs of imbalance and normalization of diet allow to achieve the correct ratio of natural and conditionally pathogenic microflora. The main role in this is nutrition, so doctors recommend table number 4.
3. The correction of the bacterial composition of the gastrointestinal tract is made by using drugs that eliminate the intestinal dysbacteriosis. These include probiotics, prebiotics, bacteriophages and intestinal antiseptics.
4. The consolidation of the achieved result, for which the patient needs to take immunomodulators.

There are three degrees of intestinal dysbiosis intensity, so prescriptions against this disease must take place not only with the patient's age, but clinical manifestations:

• 1 degree - the number of coliform decreases to 105 - 106 CFU / gor greater than 109 cfu / g, the number falls to 104 lactobacilli and bifidobacteria - up to 109.
• 2 degree - lactobacilli drop below 103 - 104, bifidobacteria - less than 108, an increase in the number of Escherichia and otherx pathogens over conditional 106.
• 3 degree - the number of colonies of pathogenic microflora exceeds 107, bifidobacteria - below 107 and Lactobacilli - below 102 - 103.

Medications and basic principles of treatment of intestinal dysbiosis in adults and childrenDepending on the degree of the disease:

1. At 1 degree - nutrition correction, vitamin preparations and enterosorbents, prebiotics.
2. At 2 degrees - in addition to the normalization of diet and consumption of vitamins, treatment with probiotics is necessary.
3. At 3 degrees - the above listed components of complex therapy are joined with the use of antibacterial agents, bacteriophages and intestinal antiseptics.

Drug groups

For dysbacteriosis of the intestine, the doctor prescribes various groups of drugs, depending on the initial pattern of intestinal microflora disorders.

Probiotics

to this class of drugs for intestinal dysbiosis include substances that contain high amounts of beneficial microorganisms.

Classification of funds is based on the microbes that make up their composition:

1. Based on lactobacilli - they are available in the form of tablets, candles or powder. The drugs are well combined with the intake of antibiotics, however, because of their unidirectional actions are not suitable for eliminating severe forms of dysbiosis.
2. Based on bifidobacteria - presented in different forms, however, tableted and rectal forms should not be used in children who have not reached the age of three. More details on how to treat dysbiosis in children →
3. Combined drugs - contain lacto- and bifidobacteria, so these drugs have a more pronounced effect and help cope with dysbiosis of varying degrees.

Prebiotics

This name is worn by substances that enter the digestive tract in the gastrointestinal tract and are a substratum for the reproduction of the natural intestinal microflora. Medicines are not absorbed, so they are removed from the intestines almost unchanged.

This group includes lactulose, fructose, inulin, galactose and other oligosaccharides. On sale are such drugs as Dufalac, Normaise and Prebio. Medications can not only restore the microbial balance, but also eliminate constipation. The relaxing effect is mild, observed three days after the start of the treatment.

These are fairly inexpensive drugs for intestinal dysbiosis, especially if you take into account the cost of domestic medicines.

Bacteriophages

This is what viruses are called that are built into the genome of bacteria and break their synthesis, as a result of which the microbe is killed. They are allowed to be used as an independent therapy or in combination with antibiotics. The application is carried out per os( through the mouth) or per rectum( through the anus in the form of an enema).

To date, the following varieties of bacteriophages have been developed for the treatment of intestinal dysbiosis in adults:

1. Staphylococcal.
2. Pseudomonas aeruginosa.
3. Protein.
4. Bacteriophage that infects the E. coli and proteins.

Intestinal antiseptics

Against the dysbacteriosis of the intestines also help drugs, whose main function is to suppress the growth of pathogenic colonies. Intestinal antiseptics are not absorbed by the mucosa of the gastrointestinal tract and do not affect the obligate microflora.

Such preparations are :

• monocomponent, ie having a part of one active substance - nifuroxazide( ersefuril);
• combined, that is, consisting of several components - derivatives of quinolones( Dependal-M, Sumetrolim).

Antimicrobial agents

Preparations for intestinal dysbacteriosis included in this group are prescribed only by a physician taking into account bacteriological examination of feces and are both inexpensive and of high cost.

Drugs in this group are selected based on the predominant species of pathogenic organisms:

1. In identifying staphylococci treatment performed macrolide antibiotic( clarithromycin), penicillins( amoxicillin) and lincosamides( lincomycin).
2. Escherichia and Proteins - the maximum effectiveness in the fight against these microorganisms showed preparations of the nitrofuran series. In some cases, doctors prescribe sulfonamides( Ftalazol).
3. Enterococci - widely used antibiotics from the group of tetracyclines, macrolides( Azithromycin) and Levomycetin.
4. Pseudomonas aeruginosa - its growth and reproduction inhibit polymyxin, carbenicillin and drugs from the class of aminoglycosides( Tobramycin, Amikacin).
5. Fungi of the genus Candida - mycosis cope with fluconazole and amphotericin B.

immunomodulators

advisability of the use of drugs to enhance immune defense due to the fact that the imbalance of the intestinal microflora, in many cases, there is violation of local immunity.

Reception of such means allows to restore in a shorter time the natural colonization of the intestine. For this purpose, medicines are used, based on plant extracts: ginseng, eleuturococcus and echinacea.

Vitamin preparations

Vitamins A, D, E, K belong to the group of fat-soluble, so their digestion is disrupted when dysbacteriosis develops. To fill the missing substances it is recommended to take vitamin complexes( Complivit, Elevit).

Overview of the most popular drugs

To cope with intestinal dysbiosis, pharmaceutical industry produces a huge amount of drugs.

Consider the most famous of them:

1. Lactobacterin - the drug from intestinal dysbiosis, included in the probiotic group, which included lactobacillus acidophilus. Produced in the form of tablets, as well as in the form of rectal suppositories.
2. Bifidumbacterin is a probiotic containing bifidobacteria. Presented in tableted form. Its complex purpose with antibacterial medicines is not supposed.
3. Floritin Forte - combined medication that contains natural inhabitants of the gastrointestinal tract and is used for the treatment of intestinal dysbiosis. It can be used even in newborns, for this purpose it is necessary to dissolve the powder in breast milk or infant formula and offer the baby to drink from the bottle.
4. Linex is a medicament from the group of probiotics . In addition to lactobacteria and bifidobacteria, it contains enterococci, which makes it the best drug against intestinal dysbiosis from this class of drugs.
5. Dufalac is a substance whose active ingredient is lactulose. This is an enzyme obtained synthetically, belonging to the group of oligosaccharides. Due to the absence of harmful effects, the drug is allowed to be used by pregnant and lactating women, and also used in infants. Dufalac helps to normalize intestinal biocoenosis, and also eliminates constipation.
6. Norme is an analogue of the previous drug, which is available in liquid form. It is forbidden to use by people suffering from lactose intolerance.
7. Hilak forte - combined formulation comprising natural representatives gastrointestinal microflora and the lactic acid, whereby the medicament can restore the natural pH.The drug can be used from birth, and also performs its functions when taken together with antibacterial drugs.
8. Acipol is a remedy that normalizes the intestinal microflora. In its composition, lactobacilli and representatives of the genus of fungi. Available in capsules containing powder. Can be used in children who have reached the age of three months.
9. Enterosgel - a product that adsorbs toxins, harmful substances, and microorganisms from the intestinal lumen. It is produced in liquid form. The medicine is not absorbed and is withdrawn 12 hours after use.

To find the right remedy, you need to consult a doctor.

The choice of drugs for the treatment of intestinal dysbiosis in children and adults is great, therefore, in order not to make mistakes in the choice of medication, you should seek help from a gastroenterologist.

The specialist will conduct all necessary examinations, including appointing tests for dysbiosis. Based on the data obtained in the study of bacterial contamination of the gastrointestinal tract, the doctor will select the necessary preparations from the intestinal dysbacteriosis.

Author: Violeta Kudryavtseva, doctor,
specifically for Moizhivot.ru

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