Overview of Drugs for Constipation

development of modern pharmacology offers a huge selection of laxatives, among which is easy to choose a cure for constipation, right on the principle of action and effectiveness.

When selecting, it is necessary to take into account the cause and duration of constipation, the age of the patient, the individual characteristics of the organism.

Before starting therapy, you should undergo a check-up, get a doctor's consultation, get acquainted with side effects with the goal of choosing the right drug for constipation.

Prebiotics in combating constipation

most sparing drugs for constipation are prebiotics - the components that make up the food, which is not susceptible to cleavage under the influenceGastric juice and enter the intestinal tract in an unchanged form, where they have a beneficial effect on the human body: they promote the growth of a usefulBacterial flora, improve the metabolism of carbohydrates, normalize the work of the intestine.

Prebiotics are considered delayed effects of the drug, as they act directly on the cause of constipation, providing a stable result compared with the drugs for constipation instant action, which bring only temporary relief.

The use of prebiotics is important for acute and chronic constipation, dysbiosis, abnormalities of the digestive tract.

They have the ability to remove toxic substances from the human body, do not allow propagating to pathogenic organisms.

most studied prebiotic - lactulose used as a basis for numerous pharmaceutical agents used in the treatment of a large number of intestinal pathologies.

effective medicine against constipation by lactulose are as follows:

1. «Normase" - means a laxative effect, enhances the formation of bile. Getting into the body, the drug blocks the release of toxins, characteristic of stool feces. The drug is prescribed to eliminate chronic constipation, the normalization of microflora, the destruction of pathogenic organisms, getting rid of dysbiosis. In the first three days, the drug is consumed in a total amount of up to 20-40 ml, then - up to 10-20 ml per day. The duration of treatment of constipation is adjusted by the attending physician and can last up to 4 months;
2. "Lactusan" - a gentle laxative medicine of complex effect. It is used for acute and chronic constipation. The drug is available in the form of syrup and tablets. Dosage is prescribed by the doctor, taking into account the age and individual characteristics of the organism. The course of treatment can be from 1 to 2 weeks. It is used from constipation for children, it can be used in pregnant and lactating women. The advantage of the drug "Laktusan" is that when it is used there is no addiction.
3. "Prelax" is a good preparation with soft laxative properties. It is used for constipation caused by various causes, with hemorrhoids and as an additional source of lactulose. Produced in the form of syrup. Dosage for adults is from 2 to 6 spoons a day, taken after meals. The duration of the course can be from 2 weeks to 3 months. With prolonged use, flatulence, pain in the abdominal cavity, diarrhea may occur. Contraindications to the use of the medicine are individual lactulose intolerance, intestinal obstruction, rectal bleeding.

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Before choosing a particular remedy, you should consult a specialist to avoid side effects.

Laxatives osmotic effects

Emptying intestine under the influence of this group of drugs is due to increase osmotic pressure and fluid accumulation in the intestinal lumen, resulting in the contents softens and expands. Among the drugs of osmotic action the most popular are:

1. "Microlax" - a solution that exerts a diluting effect on fecal masses. For convenience, it is represented by a microclyster of 5 ml. The drug is characterized by a rapid effect: removal of the intestinal contents occurs within 15-20 minutes after taking the medication. The effect of the drug "Mikrolaks" is of a short-term nature, does not cause a habit and does not affect the subsequent functioning of the intestine;
2. Karlovy Vary salt is an artificially created analogue of natural salt, which has a choleretic effect. It is used in the presence of poisoning, chronic cholecystitis, is a good cure for constipation for adults. Contraindications are intestinal obstruction, individual intolerance, not suitable for pregnant women. Among the undesirable effects can be identified diarrhea, a change in the water-salt balance, relaxation of the intestine. The drug is used in the morning: adults are bred 1 tablespoon, children from two years - one teaspoon in a glass of water;
3. "Macrogol" is an effective medicine for constipation in the elderly. Its peculiarity is the possibility to continue the course of treatment for 3 months. The medicine, like all preparations of osmotic action, is aimed at softening the feces and relieving defecation in case of constipation. The solution is taken orally during the first meal. The result is visible after 1-2 days. Accepted medication does not provoke the appearance of pain, swelling, flatulence, burning in the anal opening;
4. Magnesium sulfate heptahydrate is an inexpensive drug with choleretic and laxative properties. It is used to treat cholecystitis, hemorrhoidal formations, constipation, heavy metal intoxication. Often it is used to purify the digestive tract before a diagnostic examination. Use the medication one day, on an empty stomach, dissolving the contents of the sachet in 100 ml of liquid. Side effects include nausea, vomiting, diarrhea, increased fatigue, headache and muscle pain, dizziness. Contraindications are appendicitis, pregnancy and lactation.

Osmotic preparations can be used as a one-time aid in the fight against constipation or to remove toxins from food poisoning.

It is not recommended to use osmotic drugs in the presence of chronic constipation, if the cause of their formation is unknown.

Irritant action agents

Antipyretic drugs are the fastest in the fight against difficult emptying.

Influencing the receptors of the mucous membrane, the preparations strengthen the motor activity of the intestine, which leads to a laxative result and easier removal of stool from the body.

The most effective pharmaceutical agents for constipation are:

1. "Bisacodyl" is a cheap drug that is prescribed for acute constipation or weak motor activity of the intestinal tract in the elderly, with the goal of emptying the bowel before endoscopic or radiographic procedures, an operation on the digestive tract or delivery. Tablets are taken orally, suppositories - rectally, before bed. A single dose for an adult is 1-2 tablets or 1-2 suppositories. Relief occurs after 7-9 hours. Reception can be repeated in the morning for half an hour before breakfast. Contraindicated to use "Bisacodyl" for cystitis, peritonitis, hemorrhoids, uterine bleeding, inflammation of the digestive system. The following laxatives have a similar effect: Bisadil, Laxbene, Stadalax, Laxacodyl, Dulcolax;
2. sodium picosulphate is an active chemical compound that is the basis for pharmaceutical preparations "Guttalax", "Guttasil", "Laxigal", "Regulax", "Slabilen".They are activated exclusively in the large intestine, which comes in its original form. Local effects significantly reduce the risk of side effects. The recommended dose of a drug for constipation in the elderly is 7-8 drops dissolved in water. It is better to choose the evening time, as the medicine will work for 8-10 hours. A child older than 4 years can take 2-3 drops. The course of treatment for constipation should not exceed 7 days. Patients with high sensitivity to sodium picosulphate, with inflammatory processes in the gastrointestinal tract, with renal insufficiency or intestinal obstruction to take the drug is contraindicated;
3. suppositories based on glycerol - "Glycerin", "Glycerax" have a laxative effect due to liquefaction of intestinal contents. Encouraging hardened stool and acting on the mucous membrane of the intestinal tract, they facilitate the process of defecation."Glycerol" is a good cure for constipation for the elderly. It is effective for removing feces in those who can not exert themselves due to a disease: hemorrhoids, heart attacks, anorectal stenosis. Suppositories are used rectally in half an hour after breakfast. Removal of stool occurs 12 hours after the administration of the drug. Candles are contraindicated in the presence of malignant formations in the rectum, during the exacerbation of hemorrhoids and proctitis, as well as hypersensitivity to the components that make up the drug for constipation."Glycerol" weakens the natural process of defecation, so it should be taken with caution;
4. a large group of drugs against constipation is represented by sennosides A and B - these are laxatives based on Senna holing. These include "Herbion Laxana", "Senade", "Anthrasennin", "Tisasen", "Senalex", "Senadexin".These drugs are used to normalize the stool with hemorrhoids and constipation of various origins. It is better to take medication in the evening just before bedtime, defecation occurs within 6-12 hours. The person taking the medicine can suffer from bloating, painful sensations in this area, nausea.

Drugs against constipation should be selected individually. When choosing a remedy, always consult a specialist.

Vegetable preparations

To normalize the functioning of the intestine, to remove from the body toxic substances and to establish a natural physiological process of excreta feces will help laxatives, made on the basis of plant components.

Medicinal products of plant origin will make it possible to get rid of constipation at home and do not harm the patient's body.

Treatment of constipation can be effective and safe due to laxative dues, including yarrow, anise fruits, buckthorn bark, senna leaves, nettle, licorice root. Of these, prepare a decoction, which must drink a 0.5-1 glass shortly before sleep.

"Phytolax" - a preparation that is a biologically active additive, favors the restoration of normal functioning of the intestine: it strengthens the contractile function, improves the evacuation capacity.

It contains an extract of apricot, dill, senna, plantain. Adults to eliminate constipation should take 2 tablets in the evening after a meal.

The tablet is thoroughly chewed. The processes leading to a lax effect occur at night, so the result will be obtained in the morning. The duration of treatment for constipation is 14 days.

"Kafiol" - natural laxative, made on the basis of leaves and fruits of senna and fig fruits.

An effective anti-constipation medicine is produced in briquettes and taken by mouth through chewing.

Herbal preparations for the treatment of constipation should be taken under the supervision of a doctor.

Despite the natural origin, taking medication can have undesirable consequences: allergic reactions, headaches, weakness, dehydration, weight loss.

Contraindications to use are intolerance of the drug components, intestinal obstruction, bleeding of various origin, inflammatory processes in the abdominal cavity, pregnancy and lactation, early age.

Using laxative anti-constipation drugs, several rules should be remembered in order to avoid undesirable consequences:

• systematic administration of drugs from constipation can lead to weakening of peristalsis, and the natural feces removal process will be disturbed, therefore, the reception should be done under medical supervision;
• exposure to drugs with a laxative effect can cause dehydration. To avoid this during the treatment of constipation, you need to consume a lot of fluid.

When choosing which laxative to take, it must be remembered that most of them have a short-term effect and are aimed at eliminating symptoms, but do not relieve the pathology that causes constipation.