The norm in serum creatinine in men

Creatinine is the norm in men over the age of the table

Creatinine is an organic compound which is the final product of protein and amino acid metabolism.

It is formed primarily in muscle tissue, where enters the bloodstream and in the kidneys excreted in the urine through glomerular filtration in the kidney.

Determination of blood concentration of the compound in men is diagnostically important indicator of renal functional activity.

How shall Analysis

Determination of the concentration of creatinine in the blood of men refers to the biochemical research. To analyze blood taken from the cubital (ulnar) vein in an amount of 5-10 ml.

Blood sampling is performed in the office of the manipulation of medical institutions with obligatory observance of aseptic and antiseptic rules designed to prevent infection getting into the patient's body.

After taking the blood anticoagulant is added to the tube (Compound preventing clot formation), it sent to the laboratory, where creatinine level determination is performed using a special biochemical analyzer.

The result of the study can usually be obtained within 1 working day. For a reliable blood test results to the patient's creatinine preparation usually includes a number of recommendations, which include:

• Blood is desirable to take in the morning on an empty stomach (the last meal should be in the evening in the form of a light dinner without meat products and alcohol, in the morning allowed only mineral water without gas).
• 2 days before the study is recommended to avoid intense exercise, as this can cause a physiological increase in the concentration of the compound.
• During the 1st day before delivery of the analysis it is not desirable to use in food products, which increase the level of creatinine (coffee, alcohol, meat).
• 15-20 minutes prior to blood donation man should get some rest, sit in a relaxed position.

Implementation of such recommendations will prevent the physiological increase in serum creatinine level and get the most reliable results of laboratory research.

The norm in serum creatinine in men

Normal creatinine in men is slightly higher than in women, due to greater muscle mass. It is a relatively constant figure. creatinine concentration hardly changes with time and is the same for the different age groups.

In men, the level of the organic compound in the blood varies between 74-110 umol / L (micromoles of 1 liter of blood). In children this figure is somewhat lower due to slight muscle mass, it constitutes 45-105 mol / l. In older children, a normal creatinine level is slightly lower - 27-62 mmol / l.

During the final formation of the musculoskeletal system creatinine level reaches adult standards. Normal levels can be represented in a table:

The period of man's life	Normal creatinine in mmol / l
Child	45-105
Teenager (school age)	27-62
Adult male	74-110

Knowledge of the normal level of creatinine in the blood of male figures allows the doctor to interpret the results of research quality.

Reasons for increase

Increase in blood creatinine in men is quite common, which develops under the influence of physiological and pathological reasons. By pathological factors include:

1. muscle tissue destruction due to severe trauma, certain infectious diseases, and circulatory disorders in the tissues. In this case creatinine in large quantities released into the blood.
2. Redistribution with its reduced blood entering the kidney and the violation of the filtering process in the renal glomeruli.
3. Disruption of water-electrolyte balance with increasing concentrations of sodium salts that promote fluid retention in the body.
4. Blood loss or dehydration (dehydration) man's body, leading to a relative increase in serum creatinine level.
5. Significant reduction of renal functional activity characterized by impaired blood filtering process of the renal glomeruli.
6. Intoxication, which is a consequence of exogenous (external) Incoming or endogenous (internal) form various toxic compounds.
7. Pathology of endocrine system (various endocrine glands), which leads to a change in creatinine levels.

physiological factors also stand out, under the influence of which it is possible transient increase in the concentration of creatinine in the blood of men.

These include an increased intake of certain foods with food containing a compound, creatinine precursors (output power protein power) sufficiently fast muscle mass increase (typically the case in athletes), prolonged heavy loads on the striated skeletal muscles.

Reasons for decrease

Reduction in serum creatinine concentration in men is a rare enough occurrence. It shows a pronounced violation of protein metabolism, such as the depletion of energy substrate striated skeletal muscle phosphocreatine, which is formed from creatinine.

This may be at significant exhaustion men on the background of a long course of infectious processes as well as in the later stages of cancer development with a lot of metastases.

Also, there are several factors that may lead to further reduction in creatinine concentration in blood:

• A diet with minimal intake of protein compounds in the body, leading to a marked male emaciation (cachexia).
• Decrease in body weight in a systematic physical stress, in which the energy lost to perform muscular work, is not compensated power.
• Long-term treatment with the use of hormonal therapy of corticosteroids, which cause a gradual change basal metabolism with disintegration body's own proteins, including members of the skeletal striated musculature.

These factors, in which reduced blood creatinine levels in men require thorough diagnosis and appropriate treatment of the corresponding destination.

Additional studies with a deviation from the norm

After performing the analysis and detection of the fact of change in creatinine level in the blood of male doctor additionally appoint other research methods that accurately determine the cause of the changes:

1. Clinical urine analysis for the study of the kidneys and the exclusion or confirmation of the pathological process in them.
2. Determination of creatinine clearance to the introduction of the compound into the blood, and then subsequent determination of concentration in the urine - the study carried out for the intensity flow analysis filtering process in blood plasma glomeruli.
3. Determination of other organic compounds in the blood which also the urine excreted by the kidneys (uric acid, urea, creatine).

Also myography may further conducted, through which investigated contractility striated skeletal muscles.

Blood creatinine is informative diagnostic assay which belongs to the group of kidney performance.

A source: https://mag.103.ua/analizy/13693-kreatinin-norma-u-muzhchin/

Creatinine in the blood, the rate for men age, the table

Creatinine - an organic compound, the final product of amino acid and protein metabolism.

Material is first formed in the muscles, then penetrates into the blood, where kidneys displayed after filtering. Determination of the concentration of the compound - an important indicator of diagnosis of renal disease.

What is the rate of creatinine in the blood in adult males? This value depends on the person's age.

Indications for the analysis of creatinine

Often the reasons for increasing the concentration of the substance creatinine different. In most cases, an indication of the analysis is a suspicion of renal failure, chronic type. Alert the patient should be the following factors:

• decrease in the volume of muscles;
• difficulty urinating;
• disruption of thyroid function (increased hairy, dry mucous membranes);
• pathology of the urogenital area.

Reasons analysis in men

The increasing concentration of the substance often causes lifestyle men. Developing this condition due to pathological or physiological reasons. The former include the use of products that increase testosterone in males, muscle overload, which leads to a change in the percentage of nitrogen in the blood and creatinine.

Among the pathological factors such causes should be noted:

1. Muscle breakdown due to severe injuries, certain infectious diseases, disorders of blood circulation of the tissue. Because of this, there may be high concentration of the substance, and the kidneys do not have time to print it.
2. The redistribution of the blood, which reduces the flow of the compound in the kidney, it is a violation of glomerulus filtration.
3. Dysfunction of fluid and electrolyte balance. Present dewatering because increasing the concentration of sodium salts. This delay provokes state fluid output.
4. Blood loss provoking relative increase in creatinine concentration.
5. Kidney acute form characterized by dysfunction of the blood-filtering process kidney glomeruli.
6. Poisoning of the body due to external or internal to the formation of toxic compounds therein.
7. Diseases of the endocrine system, altering the value of creatinine in the laboratory analysis.

Reasons analysis in women

Normal levels of substance in women vary not only with age. They also depend on the complexion. In deciphering the biochemical analysis of the women's blood it is important to always take into account the possibility of pregnancy.

Doctors have developed a separate table the concentration of creatinine in the women's blood. Any deviation indicates a problem in the body.

They, like men, are both pathological and physiological natural character.

Method for analyzing creatinine

Biochemical analysis of blood determines the accurate reading of creatinine concentration. To carry out the analysis, it is necessary to select 10 ml of blood from the cubital vein.

The procedure is performed in a medical facility, be sure to following the established rules in order to prevent penetration into the body of infection.

After collection of blood is added to the test tube anticoagulant, then the sample is moved to the lab and determine the concentration of a biochemical analyzer. Interpretation of the results obtained in the study on the same day.

Preparation for analysis

To get a good value, the patient is required to perform a number of recommendations:

• analysis should take in the morning on an empty stomach;
• avoid any intensive exercise 2 days prior to the study;
• a day before a visit to the lab do not use products that increase creatinine;
• relax quarter of an hour before blood sampling, relax.

Performing such recommendations eliminates the risk of physiological growth substances that ensure the reliability of research results.

Methods for the analysis of

3 embodiment designed for determining the concentration of the compound wherein each characterized by its information content:

1. Creatinine clearance. The basis of the method is the rate of passage through the kidney blood substance. During the study, fixed ratio of blood volume to enzymes identified in the urine. This analysis shows a reliable picture. The material for the implementation of the research is daily urine.
2. Blood biochemistry. the concentration of growth gives an indication of the pathological kidney ailment. Lower values ​​indicate muscular dystrophy.
3. The ratio of the substance with nitrogen. This ratio reveals the extent of tissue dehydration.

Risks when depositing analysis

Puncture sometimes forms a hematoma - it disappears completely within a week. With a weak blood clotting should be informed about the problem of the doctor, so that he can stop the bleeding in a timely manner.

The results after analysis

Creatinine abnormalities detected by known techniques, using the formula. Sometimes the processing of biomaterials takes more than one day.

normal levels

Creatinine level is constant in a specific age, it decreases as the aging man. Ratio substance depends on the available muscle tissue, but its rate decreases significantly with age. On the connection content affects kidney function. The table lists the values ​​of creatinine according to age:

Age	Indicators (u mol / l)
Indicators to fifty years	87–150
With 60 years the rate of creatinine in the blood of men	72–111
Those who are older than 90	61–114

The ratio of nitrogen to the substance varies within 10: 1 to 20: 1. rate of excretion of urine is as follows:

Age	Norm (ml / min)
Up to 40 years	106–140
40-50 years	98–132
Indicators from 50 to 60 years	90–126
Over 60 years	82–118

false figures

Unreliable results elevated creatinine in the blood is obtained when properly produced blood sampling (too quickly and inappropriately thin needle). There are also some cases that become the cause of the increased concentration of the compound:

• the presence of the huge muscle mass, at which the healthy muscles to overstate the value of creatinine without indicating kidney problems;
• use of certain medications on the eve of the diagnosis.

The analysis should be carried out, taking into account the individuality of the patient.

Indicators below normal

Significantly reduced rate - a rather rare phenomenon. This figure is typical for problems with protein metabolism proteins. Also decline in provoking:

• anemia;
• leukemia;
• atrophy of the muscle mass in men;
• diet without protein content;
• liver disease;
• oncology.

Patients with such indicators feel muscle weakness, dizziness, loss of performance, memory impairment.

The indicators above the norm

If renal failure develops rapidly, the blood creatinine greater urinary same - less. Increasing values ​​affects physiology, provoking various pathologies. Physiological factors causing the growth of the compound include:

• the rapid increase in muscle mass (weightlifters and bodybuilders), caused by the exhausting workouts or taking growth hormones;
• high protein diet;
• antibacterial and anti-inflammatory drugs;
• shock states;
• prolonged fasting;
• dehydration.

Pathological provocateurs elevated creatinine are:

• impaired renal function;
• acute nephritis;
• chronic pyelonephritis;
• cancer;
• damage to muscle tissue;
• prolonged compression of tissues;
• diabetes;
• thermal burns;
• certain endocrine disorders in which the thyroid gland produces a large number of hormones;
• heart failure.

Unpleasant symptoms of kidney, if not cure them, can cause complications such:

• discomfort in the lumbar region, is gradually developing into a constant aching pain syndrome;
• high blood pressure;
• swelling;
• kidney disease, causing troublesome urination.

You can not use the study for early detection of abnormalities of the kidneys. Growth performance occurs only when defeat most of the body.

Stabilization of the concentration of creatinine in the blood

To restore the index requires treatment. If, however, a slight excess, just enough to change lifestyle, to limit the consumption of meat products. Add the vegetables to the menu, vegetables, cereals. Prefer baked bread with bran. Drink plenty of fluid fasting and between meals.

When the creatinine concentration increased provoked strenuous physical exertion required to reduce them. To prevent serious disease, it is recommended to periodically survey. If the concentration of the substance does not fit the norms, will certainly go a survey to take adequate steps to restore the normal state.

increased creatinine

Increase the level of a substance. For this:

• Increase daily physical activity at the same time trying not to overtax the body too;
• Sleep at least 7 hours and lying down in the bed is not too late;
• change the diet: Eat foods rich in protein;
• drink more water, if the kidney cope with its processing;
• take to fill protein deficiency of vitamin and mineral agents.

lowering creatinine

When the concentration has increased slightly, it provoked a certain physiological adjustment of the organism. In such a situation will help:

• Power correction. Add in the diet of lean meat, eating it at least three times a week. To normalize digestion, eat porridge.
• Provide a full-fledged drinking regime. Daily drink at least 2 liters of plain water.
• It should also reduce the physical load.

But if the deviation provoked renal pathology - therapy should only deal with doctors.

A source: https://pro-analiz.ru/krov/norma-kreatinina-u-muzhchin-v-krovi.html

What creatinine values ​​are normal in men?

Creatinine - final matter obtained in the process of protein conversion. It is produced in muscle tissue and secreted into the circulatory system. The more men muscle muscles, the higher creatinine levels in the blood.

Output only through the urinary system, therefore, is an important indicator of kidney function. If lifelong human being has the same constitution, the creatinine level will be constant.

Available pro creatinine

Indications for analysis

Any deviations in the operation of the kidney and muscle tissue are indications for analysis. Can cause anxiety symptoms and following diseases:

• Urinary problems (pain, cramps and other unpleasant sensations).
• Dystrophy muscle tissue.
• Diseases of the endocrine organs.
• Renal insufficiency.
• Observation of the dynamics in the treatment of renal or urinary system.
• Pregnancy, since in this state, the load on the kidneys is increased in times.

Information about that, why do we need to carry out this analysis

REFERENCE! Spent on analysis and decode it Only a doctor can.

Analysis

Creatinine levels in the body can be found in several ways, which differ in information content:

• Blood chemistry.
• Creatinine clearance: the ratio of the number of enzymes in the urine to blood quantity. Clearance - a body's ability to purify the blood from harmful substances.
• The ratio of nitrogen and creatinine. It is used to determine the degree of dehydration.

REFERENCE! The most informative method is the definition of creatinine clearance. The highest concentration of creatinine is observed in the eveningAnd the lowest in the morning.

Preparation for analysis

Blood chemistry:

• Blood must be collected in the morning on an empty stomach.
• In just a few days to minimize the amount of meat products in the diet.

Read also: Investigated together what seromucoid?

Biochemical analysis of urine:

• Careful hygiene of the genital organs, but without the use of chemicals that kill the natural microflora.
• The day before the assay should be consumed about two liters of pure water (physiological rate for an adult human).
• Rules collect daily urine: after you wake up you must urinate (this urine collected is not necessary), all subsequent times (for 24 hours) urine should be collected in a container and storing it in a dark cool place. The last portion of urine should be a morning urine the next day.

Norma men

creatine levels decrease with age, with a decrease in muscle tissue.

The norm in the blood:

Age	Creatinine, mmol / l
from 18 to 60 years	87-150
from 60 to 90 years	72-114
more than 90 years	61-114

Norma creatinine in urine liberated per day, depending on body weight and physique. For men, the rate of 122-220 micromoles per kilogram of body weight. The norm in nitrogen and creatinine ratio is from 10: 1 to 20: 1.

Creatinine clearance in men:

Age	ml / min
from 18 to 40 years	106-140
from 41 to 50 years	98-132
51 to 60	90-126
61 to 70	82-118

REFERENCE! With the progression of kidney disease in the blood creatinine level rises, and in urine, on the contrary, it reduced.

Abnormalities

Deviations from the norm is not always svidetelstuet of serious diseases. Raising or lowering the level of creatinine in the blood may be a physiological norm in a certain way of life.

Vegetarians, athletes with large muscle mass, models and dancers, who adhere to a strict diet.

In these cases, deviation from the norm is not as criticalAs in pathologies of internal organs.

Level up

The reasons for the increased level of creatinine in the blood can be caused by physiological factors and the development of serious pathologies.

Read also: Causes and treatment of elevated creatinine

Physiological factors include:

• Set a large muscle mass, such as athletes and bodybuilders heavyweights.
• The predominance in the diet of animal protein.
• Acceptance of anti-inflammatory drugs, "Ibufrofen", "Nurofen".
• The use of antibiotics.

Pathology of the disease include the following:

• Renal failure in any form.
• Disruptions in the endocrine system. Thyroid disease associated with its increase, and excess hormones.
• Violation circulatory systems in heart muscle, which leads to renal tissue hypoxia and lowers their performance.
• Oncological diseases.
• Damage to muscle: traumas and fractures Crush Syndrome.
• Dehydration (an increase of blood counts).
• Diabetes.

If you do not treat kidney disease, it can cause a number of complications:

• Urinary problems from complete retention of urine in the body to over-allocation (up to two liters per day).
• Constant aching pain.
• Swelling (due to fluid retention in the body).
• Increased blood pressure.

IMPORTANT! Creatinine level unacceptable for the early diagnosis of diseasesAs well as an increase is observed in lesions mostly kidneys.

How to reduce the level of

Recommendations to reduce the level of creatinine vary, depending on the reasons for the increase. If the level is increased slightly and the survey did not reveal serious renal disease, you should follow these tips:

• It is necessary to normalize the diet. For an adult human in need of weekly meat is 450 grams (150 grams, 3 times a week). Meat should not be too fat and high-calorie, suitable rabbit, veal, chicken, turkey. The basic daily rate of protein is better prepared from products of plant origin. Enrich your diet foods rich in fiber to normalize bowel function: porridge (oats, buckwheat, millet), bran bread.
• Correct dehydration. An adult should drink more than two liters of clean water. By that hard to get used, so keep a record of the number of drunk, take a bottle of water to work or walk. Remember that the most important technique of water - in the morning on an empty stomach.
• Reduce physical activity. If you are a professional athlete, for the sake of his health is better to skip the competitive season and to restore the functioning of kidneys.

See also: Learn rules of creatinine in the blood

If in addition to the increased level of creatinine diagnose serious kidney disease and urinary tract, the treatment must take place strictly under the supervision of a specialist. The main treatments for kidney failure:

• Appointed by medication drugs aimed at the normalization process of protein breakdown.

ATTENTION! Self-regulate blood creatinine level is dangerous for health.

Causes and symptoms of low level

Symptoms are mild, there is a general weakness in muscles, dizziness and a reduction of efficiency. creatinine level decreases because of the following diseases and conditions of the body:

• The first six months of pregnancy.
• Anemia, anemia.
• The sharp decrease in muscle tissue (extremities failure).
• Improper diet (no protein).
• Starvation, anorexia.
• Leukemia.
• Paralysis.

The risk at the time of analysis

• At the puncture site may form a bruise or hematoma, which will take place on their own within a week.
• If you have poor blood clotting, be sure to inform your doctorTo take measures to stop the bleeding.

Approximate prices for Analysis

Laboratory	In blood	creatinine clearance
"Invitro"	460 rubles	750 rubles

Additionally, you can watch another material that can be useful. Athlete talks about the various blood tests, including creatinine and about

A source: http://1pokrovi.ru/analizy-krovi/bioximicheskij-analiz/pokazateli-belkovogo-obmena/kreatinin-u-muzhchin.html

The norm in serum creatinine in men by age

Creatinine is produced after the protein conversion. The substance is produced in muscle tissue, and then released into the bloodstream.

The volume of its production depends on development of muscle men. Displays it in the urine. If creatinine in the blood of men in norm - human kidneys are working without sboov.

At constant physique creatinine level is stable throughout life.

Reason to get tested

Indications for tests - abnormality in the muscle or kidney. Particular concern should call the following factors:

• urinary discomforts due rezey, pain and other sensations;
• dystrophy;
• hormonal disorders;
• kidney problems.

Test results are also needed in the treatment of the entire urinary system, or kidneys in particular. Girls they are needed during pregnancy, because it is accompanied by an increase in the load on the kidneys.

Types of checks and preparation for them

There are several ways to find out the level of creatinine. They differ informative:

1. Blood chemistry.
2. Creatinine clearance. Clearance is called the body's ability to blood purification from worthless substances. It is measured in the study of the ratio of the enzymes in the blood to their number, while it is in the blood.
3. Balance nitrogen and creatinine. It is relevant to determine the possible dehydration of the body, if necessary.

A more effective method in this list is considered to be a study of creatinine clearance. It plays an important role for analyzes, because the concentration of the substance grows in the evening. These and other nuances you need to know to be ready for all types of checks - it's important to obtain reliable information about the body.

In the study of urine:

• Carefully prepare the genitals to the procedure. It is prohibited to use chemicals, adversely affecting the natural microflora.
• About two liters of bottled water to drink per day prior to analysis.

We must not forget about the rules of the urine collection. First you have to go to the bathroom immediately after waking up. You will not need to collect the urine - accumulates only the material that is displayed for all of the following day. Thus urine container should be stored in a cool place protected from light. Last piece - the one that the examinee will receive the next morning.

Men's regulations

With age, muscle mass is reduced as the amount of the substance. It looks like a table with a creatinine standards in men age.

age of the patient (s)	blood creatinine content in micromoles per liter (mmol / l)
18−60	87−150
60−90	72−114
90 and more	61−114

The choice of the upper and lower limit of the determination of creatinine in urine standards depends on the human body, as well as the weight of his body. The men considered normal: 122-220 umol creatinine per kilogram; nitrogen balance and creatinine of 10 to 20 to one.

Creatinine clearance is normal in men corresponds to the table.

age (years)	output rate (ml / min)
18−40	106−140
41−50	98−132
51−60	90−126
61−70	82−118

Delivery of any analysis is accompanied by a health risk. Patients should be sure to inform your doctor about low capacity of the blood clot and diseases associated with a strong decrease in immunity. Hematomas and bruises, that sometimes appear on the puncture site, usually held towards the end of the week.

Abnormalities

Non-compliance - not always a cause for panic. Sometimes increasing or enhancing quantity of substance - physiological rate for a particular life image. Example: model, vegetarians, dancers, athletes. they all adhere to strict diets, so an abnormality in their case quite uncritically and does not indicate violations of the organs.

The reasons for exceeding the

Increased creatinine levels may indicate the development of pathologies the treatment of which should not be delayed. Distinguish physiological and pathological factors.

Natural causes:

• Step increasing muscle mass in sports.
• Diet with lots of animal protein.
• Admission of antibiotics and antiinflammatory drugs.

But this is not true of such diseases in which creatinine level is also increased:

• Renal insufficiency.
• Disruption of the endocrine system. They may relate to problems with the thyroid gland - it increases because of an overabundance of hormones.
• Oxygen starvation of renal tissue can be caused by malfunction of the circulatory system. Of course, the body can not function properly with a lack of necessary materials.
• Cancer of any type and stage.
• Injuries to the muscle tissue.
• Diabetes.
• Lack of water in the body.

These diseases are sure to be treated. Otherwise it will lead to complications:

• The increasing complexity of the problems with urination. Urine may be delayed or completely in the body, which is fraught with rupture of the bladder, or undue prominence, it is dangerous to full dehydration.
• Aching pain in the lower back.
• General swelling of the skin.
• The growth of blood pressure.

Creatinine level helps only in the later stages of kidney disease. The method is useless in the early diagnosis: at this point the kidney is not affected. However, it helps to detect in the early stages of the disease, only indirectly related to this body.

Methods normalize content

Depending on the reasons for the increase should be resorted to different methods. With a slight increase in the amount of creatinine, when at the end of a more serious examination no abnormalities were found, enough to take advantage of these tips:

1. Monitor the diet. An adult should have only a pound of meat per week, dividing them into several portions. Optimal - 3 days 150 grams. In this case, it is necessary to monitor the quality of the meat - it should not be too fat and high-calorie. Rabbit, veal, chicken, turkey - apply. The basic daily rate of protein is best to fill with food of plant origin. It is better to take care of the gut and eat more foods rich in fiber. First of all - it's bran bread and cereal.
2. Monitor the amount of water you drink to prevent dehydration. The norm for an adult - more than two liters. A person who drinks a little, it will be difficult to get used to it. In this case one can make notes and record all drunk liquid into it, and take with water to work. It is necessary not to forget to drink one glass of fasting. Receiving liquid and can be fruit drinks and herbal teas. But if a person is afraid to eat too much sugar or suddenly discover allergic to a plant, it can just drink pure water.
3. Regulate the exercise. If a person is not engaged in sport on a serious level, it just took a little break. Even professional athletes better to refuse to participate in the competitive season for the sake of their own health. This time is enough for the full recovery of renal function.

If found serious pathology, required mandatory treatment. Medical procedures to correct problems of the urinary system and the kidneys are determined by your doctor.

Usually doctors prescribe drugs needed to bring the processes of protein breakdown in the norm.

Trying to control their own level of creatinine medication way is strictly forbidden - it is dangerous to health.

Symptomatology lack substance

Symptoms of deficiency are mild creatinine. General muscle weakness, malaise and performance accompany many diseases, so keep track of it is difficult to decrease the norm.

By lowering the amount of substance result:

• the first six months of pregnancy;
• anemia, and anemia;
• rejection limbs and a sharp decrease in muscle tissue mass, paralysis;
• leukemia.

This is possible when disturbed ration (partial or complete absence of proteins, including plant), starvation and anorexia.

Investigation creatinine clearance helps diagnose many problems with health. Among these are diseases that are associated with kidney both directly work or indirectly. One should not ignore the direction of a doctor for analysis or a full examination: it is an effective method for the detection of diseases, is not developed to the stage problematic to treat.

Testimonials

I donated blood for analysis. First got results and got acquainted with them, I did not understand. Then the doctor told me what the rate of creatinine in the blood of men. After that, I almost froze - I had too much performance.

It turned out that it is only due to malnutrition - I ate too much meat. If everything went well, I would just put the liver and kidneys.

No need to give up medical examinations just because of laziness or empty faith in their own health.

Maksim

A year ago, I passed a comprehensive examination, including making this analysis. The doctor said that my performance in serum creatinine is normal, as well as clearance, but, but he still suspected that I have any kidney problems.

At first I did not understand it - like, such analyzes precisely diagnose the state of the urinary system - but agreed to a deeper investigation.

As a result, we have cured the disease at an early stage - if I refused and waited, then everything would be much worse.

Edward

Once I realized that the whole week feel some inexplicable weakness. I really could not bring myself to work. For some reason decided that the need to pass tests.

When I looked at the results, I saw very little value for the number of creatinine contained in blood. At first I thought that for a girl that's fine.

However, the doctor said that women over the age of creatinine rate differs from the male in about half (it is smaller). I was scared even more.

My husband and I tried for a long time and so have a baby, and if I showed some serious problems with the kidneys, the family of such plans could forget. After passing the comprehensive examination, doctors found no abnormalities. But I soon learned about the beginning of pregnancy, because of which matter has fallen and content in my body. My joy knew no bounds.

Victoria

A source: http://nebolel.com/analizyi/norma-kreatinina-v-krovi

What is creatinine: a norm than an increased level of danger

What is creatinine in blood tests, and why we need his record hardly knows ordinary visitor clinics. He thinks he (or she) is like this: "Well, here I immediately wrote creatinine.

And even the rate of creatinine is shown. And what to do with these indicators do? ".

Of course, a sheet with the results of the blood test comes to the doctor and the illegible handwriting writes in the book a lot of unknown.

Naturally the desire of many recipients by a physician at least something out for themselves. Investigated.

Creatinine - is an important chemical compound in the human body, which is formed by the decay of protein molecules. This material is an integral part of the residual nitrogen.

At the beginning of the chain of transformations necessary creatine. This component carries out a long path through the body, since in the renal parenchyma. Methylation occurs in the liver. After this matter is sent to the muscles, which is created from creatine creatine. The resulting component goes into myofibrils, where it splits into creatinine and phosphate, giving muscles for energy reduction.

After using the remnants of the blood followed. The liver is not exposed to creatinine since due to its structure, and without the hassle excreted in the urine. This energy circulation occurs continuously, because of this, the amount of substance in the circulatory system remains the same under normal condition of the body.

creatinine content depends on the condition of musculature and human kidneys. Also on its level in the body affected by age and gender. Elevated levels of this substance says about changes in the kidneys.

energy revolution

The above-described process of converting creatinine to creatine using the received energy rather complicated. However, we use the result of unconsciously. Who in your life to think that I have to raise my hand, and this should go here such here biochemical processes? That's right - none. But they are as a person is a "biochemical machine."

Everything happens instantly literally running commands from the brain. Suppose you decide to pour himself a cup of tea in a kettle. How does this happen? You have to raise your hand, take the kettle, bring it to a cup and pour. Whereby the origin of all these movements? Due to the energy that gives (allocates) creatinine muscles.

Do not delve into a complex process, but it is quite clear that to perform an action by our muscles should be allocated the necessary amount of creatinine (ie, energy). This amount is determined by our body itself, depending on many factors. Including on the training of muscles.

It is no accident so-called "pitching" gyms often use special supplement called "Creatine". Ostensibly these additives are added to the raw material to convert it into creatinine that seemingly allows you to pump up the huge muscles. In fact, these additives do not work (tested by the author of this article) so we would like.

So, the use of dedicated energy, the body is unable to process any way superfluous and excess creatinine should be withdrawn from the body.

creatinine level

This indicator is totally dependent on age and sex, as well as kidney operability accumulated muscle mass and preferences in food intake. In the human circulatory system contains 2 kinds of biologically active substances, endogenous - which is formed directly in the body - and exogenous (supplied from outside).

Therefore, if the serum creatinine level is slightly higher than the norm, and the person who has passed the tests, has athletic build, and does not apply to people who eat only plant foods, there is no reason to concern.

On examination, the patient should also take into account his age category. If it is the elderly, the creatinine level is lowered, therefore, the results of the analysis simply state age-related changes of the body.

We draw attention to the fact that the rate of creatinine for the different sexes is different. This can be explained by the fact that the strong half endowed with greater muscle mass, which must be set in motion (and therefore energy must stand out more) than women (usually roundness appear due to fat deposition, which produces a reduction and does not need additional energy).

In childhood and adolescence creatinine changes accordingly age category.

Normal creatinine in mg / l:

• newborn baby up to 1 year from 3.0 to 11.0;
• from 1 year to 7 years from 2.0 to 5.0;
• from 7 to 14 years, from 3.0 to 8.0;
• from 15 to 16 years from 5.0 to 11.0;
• Men from 8.4 to 13.6;
• women from 6.6 to 11.7.

The analysis may also be used other units - a micromoles per liter (mmol / l). In this case, the normal rate will be considered in women range from 44.0 to 97.0 mmol / l, and for men from 44.0 to 115.0 pmol / l. This indicator is most often determined in the urine. In a healthy person with a urine output of up to 2 grams of creatinine per day (rate from 1 to 2 g).

creatinine level differs between men and women by the fact that the female half metabolic processes body proceed more slowly, and the different diet, has the effect of hormones, especially during pregnancy.

Children of different sexes to 14 years, the content is the same level of creatinine.

How dangerous elevated creatinine

Creatinine slight deviation from the norm can not be considered for the problem because a person is in constant energy metabolism and in the next moment the excess energy can be used. But the dangerous state when the creatinine rate exceeded seriously?

Recall that the body is nothing to creatinine can not do, but to bring it. Due to some reasons arising from the withdrawal of the problem lead to the accumulation of creatinine in the blood. Accumulates in the blood over a measure creatinine begins to exert a toxic effect on the body's system, gradually increasing their poisoning.

Often that too high a level leads to the need to conduct dialysis (blood purification) not to cause the body to fracture.

Research on creatinine

The main task blood test creatinine, which may recommend a doctor - is to identify the disruption of the urinary system (mainly kidneys).

The fact is that the good work of the kidneys with no problems and the withdrawal rate of creatinine is observed.

But above normal may indicate the presence of any hidden diseases, kidney disease, namely renal failure.

A blood test for creatinine needs to be done if:

• You are a kidney donor;
• Do you have a suspicion of renal failure, urolithiasis, or muscle system diseases;
• To determine the precise dosage of the drug with a toxic effect on the body.

In order to identify the content of creatinine in the blood system need to donate blood for biochemical research. To obtain accurate measurements, per day to abandon the use of alcoholic beverages, coffee, strong tea, and do not abuse the protein food such as meat. Abandon the high physical loads.

The analysis is taken on an empty stomach in the morning from a vein. Before any analysis needs some time to sit in a calm and relaxed state. analysis of studies begin immediately. The result will be ready on the same day.

sample Rehberg

Otherwise, this test is called "creatinine clearance" and is a more thorough method of determining its level. It detects the presence of renal failure and the impact of blood flow through the renal glomeruli. For its implementation shall be two biological environment of the body - it's urine and blood.

A blood test is done in the morning on an empty stomach.

Urine was collected for 24 hours, except for the portion after a night's sleep.

All collected samples are poured into a container of 5 liters and kept in a cool dark place. After the final urine sample in a separate container part of the molded urine (enough 30 mL) and submit for analysis in the laboratory.

For the reliability of the results the following conditions must be met:

• It is necessary to abandon the use of drugs or inform the doctor about the use of them in advance;
• Observe hygiene rules for the genitals;
• Contraindication for taking the analysis are the female half monthly uterine bleeding.

Upon delivery to the laboratory in a hospital need to enter your weight and height.
The result represents the rate of purification of the biological fluid and creatinine indicated in milliliters per minute.

Reberga sample is assigned to the disputed cases where ordinary analysis sufficient. But in fact, modern medicine is constantly improving and finding new methods of diagnosis.

Reference. Despite the fact that the analysis in the creatinine level is used for a long time and is widely enough lately medical community is inclined to the fact that more precise marker for detection of renal disease is a protein cystatin C.

A major long-term study of almost proved that cystatin C is able to predict the development of chronic kidney disease and cardiovascular disease in the elderly. A very important research conclusion!

Reasons creatinine abnormalities

The main reasons for increasing the level include enhanced its production process, elimination or degradation of the substance from the body. However, elevated creatinine can also occur in the following pathologies:

• Liver disease of toxic, inflammatory and cirrhotic;
• Necrotic tissues and the internal organs of the body;
• Renal failure;
• A disease associated with excessive formation of thyroid hormones;
• Injury muscular and skeletal systems, and large-area burns;
• Complication of diabetes caused by vascular lesions in the kidney;
• An excess of the adrenal cortex;
• The disease is characterized by weakness of the skeletal system;
• Diseases of the pulmonary system;
• Long febrile illness;
• Gestation period;
• Exposure to drugs that have toxic effects on the kidneys;
• The increased load on the muscular system.

By reducing the content of this component results:

• Starvation;
• Gestation period;
• Long-term treatment with corticosteroids.

It should be noted that in pregnancy and during starvation may occur as a reduction or increase in blood creatinine levels.

Symptoms of elevated creatinine

Awareness may be accompanied by the following symptoms:

• weakness, drowsiness, lack of energy;
• nausea;
• headache;
• hard breath.

Accordingly, the highest rate of creatinine in the blood is an indirect indication of renal failure, destruction and inflammation in the musculoskeletal system, or the presence of infectious diseases involving lesions kidney.

How to reduce blood creatinine

Attention! Tutor is highly undesirable decrease in creatinine levels. It is necessary to consult a specialist to determine the most appropriate treatment or compliance with dietary restrictions. If the high rate is the result of a disease, it is necessary to deal with the root cause of this disease.

If the reason lies in the wrong diet, it is recommended to refuse the following products:

• Oil-rich fish and meat;
• Smoked and spicy foods;
• Milk and lactic acid products;
• cheeses;
• Strong coffee and tea;
• Salt and sugar.

In general, you should limit itself to the use of food rich in protein and salt, and it is better to move on Products containing antioxidants (cabbage, beans, pistachios, walnuts, oranges, strawberries, eggplant and others). And also it is recommended to use at least 1 liter of pure water.

To reduce creatinine specialist may prescribe medications such as Lespeflan, Ketosteril, Lespenefril and others.

It may also be recommended such different medicinal herbs charges and correction of physical activity.

At very high levels of creatinine hospitalization in specialized department of a hospital. In extreme cases, conduct artificial blood purification system using the apparatus "artificial kidney".

Attention. Elevated creatinine refers to the first "bells" about the presence of any serious pathology, so it is imperative to find and eliminate the cause.

A source: http://serdcet.ru/kreatinin-v-krovi.html