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Pantogam in the treatment of neurological diseases

Contents:

  • Mechanism of action
  • Indications for use
  • Side effects and contraindications
  • Method of application

Assign Pantogam to an adult Pantogam is a nootropic drug similar in chemical composition to the natural mediator of the nervous system by gamma-aminobutyric acid. The active substance is gopantenic acid. What is the purpose of adult Pantogs? It is used for the treatment of alcoholic intoxication of the nervous system, hyperactivity syndrome in children, and also for the prevention of Parkinson's disease. Suppresses convulsive activity with episendrome and other pathologies of the nervous system.

Mechanism of action

Pantogam is an oxyacetic acid, similar in chemical structure and action with gamma-aminobutyric acid( GABA), which is the inhibitory mediator of the nervous system. GABA reduces the overall excitability of the central nervous system. Glutamic and aspartic acids have an exciting effect on the nervous system.

Normally, the balance of excitation and inhibition is maintained by the body itself. However, with intoxication( ethyl alcohol, narcotic substances, taste enhancers) and circulatory disorders, the regulatory mechanisms are violated.

To eliminate excess excitement leading to aggressiveness, hyperactivity and dissociation of attention, a preparation containing gamma-hydroxybutyrate of calcium is used. Pantogam is able to increase the resistance of the brain to hypoxia in cases of circulatory disorders in the brain, as well as in alcoholic intoxication. Produced in the form of syrup and tablets. Analogues Pantogam in tablets - Gopantam, Calcium Gopantenate, Pantokaltsin.

Indications for use

Hopanthenic acid, Pantogam indications for use:

  1. Small cerebral dysfunction in children( including cerebral palsy with convulsive syndrome).
  2. Extrapyramidal disorders( hyperkinesis such as epilepsy, chorea, Wilson-Konovalov's disease).
  3. Nervous exhaustion and mental fatigue.
  4. Convulsive syndrome of various origin.
  5. Disorders of urination and defecation associated with brain damage in the intrauterine and ancestral periods( enuresis and encopresis).Hyperactivity of the bladder in adults.
  6. Mental retardation in children, dementia in the elderly.
  7. Neuroses in adults and children.
  8. Stuttering.
  9. Syndrome of hyperactivity and attention deficit.
  10. Alcoholic brain damage and abstinence syndrome.
  11. Vegeto-vascular dystonia.
  12. Post-stroke state.
  13. Schizophrenia having an organic substrate.
  14. Disorders caused by taking antipsychotics.
  15. Nerve ticks in children and adults, muscle twitching( fasciculation) with neurosis.

What helps Pantogam? Acting on GABA-receptors, gopantenic acid reduces the excessive activity of the nervous system in alcoholic intoxication, the syndrome of hyperactivity, irritability.

In addition, Pantogam acts as a light anticonvulsant, which allows it to be used in various diseases associated with extrapyramidal system damage. Used for all types of epilepsy( myoclonic epilepsy including), convulsive syndrome with cerebral palsy in children.

Important! When alcohol intoxication reduces the stimulating effect of ethyl alcohol on the glutamate transfer system. The use of Pantogam facilitates the course of the withdrawal syndrome with alcoholism and drug addiction.

In elderly people Pantogam restores memory processes, eliminates irritability and aggressiveness. Prevents Parkinson's disease, tk. Suppresses the pathological hyperactivity of neurons and reduces the excitotoxic effect of glutamic acid.

Hepattenic acid is used for children with hyperactivity syndrome who have problems with academic achievement due to increased excitability of the nervous system. Suppressing the activity of glutamate transfer in the brain leads to more stable behavior in children in the classroom. In addition, hapantenic acid increases the ability to teach the child to writing, reading and counting.

Pantogam and its analogues are used in psychological and mental overloads for the prevention of nervous exhaustion in adults and children. The drug reduces the conflict of personality.

Side effects and contraindications

Side effects of Pantogam Side effect of Pantogam:

  1. Allergic reactions.
  2. Drowsiness, retardation.

It should be taken into account that glycine is also a brake meiator of the nervous system, therefore its preparations intensify the action of gopantenic acid. Etidronic acid also potentiates the effects of Pantogam. The drug enhances the effect of local anesthetics. Contraindicated Pantogam under the following conditions:

  1. Pregnancy and feeding.
  2. Severe renal insufficiency.
  3. Intolerance to the drug.
  4. For syrup - phenylketonuria, due to the content of aspartame.

How to use Pantogam? For this it is necessary to consult a neurologist. With increased excitability and irritability in adults and elderly people, one tablet( 0.25 g) 3-4 times a day is used. If necessary, increase the dose.

In order to eliminate the side effects of antipsychotics in organic schizophrenia, doses up to 3 g per day are used. Adults with a hyperactive bladder appoint 1-2 tablets( 0.5 g) 3-4 times a day.

How to apply Pantogam to children? With neurotic conditions, accompanied by tics and fasciculations, children are given 1-2 tablets( 0.25 g) 3 times a day. In the case of enuresis and encopresis( the flow of feces) with organic brain damage apply a dose of up to 3 g per day. The course of treatment - a month. Before using the drug, a consultation with a doctor is mandatory. Drivers and operators of complex mechanisms Pantogam is not recommended.

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