Application of venlafaxine

preparation Each person in life there are difficult periods. Some people easily cope with difficulties, while others fall into depression, which is hard to get out of. To help such patients overcome the oppressive feeling, the doctor prescribes special treatment. The basis of therapy is a group of drugs called "antidepressants."Recently, venlafaxine or its analogs are often used. This drug was among the four best drugs tested in 2009, and remains one of the most effective antidepressants. As

acts

Venlafaxine Venlafaxine hydrochloride - is unique in its chemical action of a substance that does not belong to the same subgroup antidepressants. Getting into the body, the drug affects the activity of neurotransmitters, greatly enhancing it. Selection of the target depends on the amount of active ingredient: effect on serotonin activates when receiving up to 125 mg, increasing the dose to 225 mg - activated noradrenergic effect, to 375 - dopamine.

The substance is well absorbed in the gastrointestinal tract( GI tract).Assimilation occurs regardless of the presence of food in the stomach. It is important to remember that venlafaxine is bonded to proteins that circulate in the blood plasma, and this contributes to its penetration into breast milk. Metabolism of the drug occurs in the liver. It is excreted mainly by the kidneys with urine after 72 hours.

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Instructions for use Venlafaxine

venlafaxine or its analogues( Velafaks, Dapfiks, Velaksin) appoint a doctor after examination of the patient. Do not engage in self-medication, since any drug has contraindications and dosages. Venlafaxine is used to treat depression, panic disorders and social phobias. Sometimes the drug is used to treat migraine or polyneuropathy, which is caused by diabetes.

Dosage

Dosage is selected depending on the expected effect. At appointment the condition of internal organs of the patient, especially a liver and kidneys is considered. Take medicine is recommended during meals, squeezed with a small amount of water. We must try to do this at the same time of day. It is forbidden to chew the medicine, dissolve in a liquid or divide into several receptions.

At the beginning of treatment, the daily dose should not exceed 75 mg, in the future the dosage is gradually increased. Patients with kidney or liver pathology treatment are selected individually with a minimum dosage of the drug( the dose is reduced by half).The medicine is addictive, so the abolition is gradual. If the reception lasted more than one and a half months, the dose is reduced for a minimum of two weeks.

Contraindications

Venlafaxine has a number of contraindications:

• children under 18 years;
• severe disorders in the functioning of the liver and kidneys;
• tendency to bleeding;
• presence of arterial hypertension;
• episodes of seizures in the anamnesis;
• angina or infarction;
• glaucoma;
• manic states.

In some cases, the drug may be taken. But only the doctor can do this after calculating the intended benefit and harm to the patient.

prohibited reception Venlafaxine people with allergic reactions to make up the formulation components, as well as patients who are taking or have taken MAO inhibitors( antidepressants used in parkinsonism and narcolepsy).To allow the reception of venlafaxine, should take 14 days after the withdrawal of MAO inhibitors.

With care, prescribe medication for people with low body weight, as venlafaxine contributes to its even lower. If the patient is obese and takes therapy to get rid of excess weight, select an analogue of venlafaxine or control the state of the body.

Pregnancy and lactation

It is not recommended to take the drug during pregnancy, especially in the first trimester, as it has a teratogenic effect. Assign only if safer options are ineffective and there are no other means of fighting the disease. If you have to take venlafaxine, then the baby should be stopped feeding. This is due to the fact that the active substance has the property of passing into breast milk.

Side effects of

Severe side effects alone are rare, most often they are caused by violations of the instructions for the use of venlafaxine. Undesirable reactions are divided into several groups depending on the body's response:

• general condition - weakness, Quincke's edema, occasionally anaphylactic reactions;
• sense organs - decrease in smell and hearing, tinnitus, mydriasis( dilated pupil), disruption of accommodation of the lens;
• nervous system - decreased sexual desire, headache, sensitivity disorder, seizures, apathy, tremor, dizziness, suicidal thoughts, manic behavior, aggression;
• heart and blood vessels - pressure disorders( hyper- or hypotension), tachycardia;
• GIT - bruxism( grinding of teeth), diarrhea or constipation, nausea, vomiting, decreased appetite;Sometimes prolonged use of the drug provokes the development of hepatitis or pancreatitis;
• respiratory system - shortness of breath, pneumonia;
• genitourinary system - impotence, anorgasmia, pollakiuria, menstrual disorders, incontinence or urinary retention.
• skin - increased sweating, rashes, erythema.

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Reviews about the drug

You can not buy an antidepressant without a prescription in the pharmacy. The price for venlafaxine 75 mg ranges from 350 to 500 rubles per package for 30 pieces. The form of release for 37.5 g will cost a little cheaper - from 250 rubles for 30 tablets. It is important to store the drug in a place inaccessible to children, since it significantly affects the child's nervous system.

Judging by the opinions of doctors and patients, venlafaxine quite often causes minor side reactions. At the time of taking the drug, the dose is carefully selected. At the first side manifestations the drug should be replaced or adjusted dosage. More information about the drug, find out from the video: