Rinza: instruction on the use of tablets, analogues
Jul 08, 2018
Rinza is a combined preparation for the symptomatic treatment of colds and ARVI( including influenza).It helps reduce the severity or stop the febrile reaction, pain and cold( nasal congestion and rhinorrhea).Table of contents: Active components and form of release What helps Rince?In which cases can not apply Rince?Recommended doses Side effects Mechanism of action Overdose Interaction with other drugs Additional Rince during pregnancy Storage and dispensing conditions from pharmacies Analogues Rings
Active ingredients and form of release
Rinza is produced in tableted form.Each tablet contains 500 mg of paracetamol, 30 mg of caffeine, 10 mg of phenylephrine hydrochloride and 2 mg of chlorphenamine maleate.
The drug is supplied in blisters for 10 pieces.
What helps Rince?
This pharmacological agent is indicated for influenza and other acute respiratory viral infections, as well as for colds. Rinza does not affect the cause of pathologies( i.e., bacteria and viruses) and does not reduce the period of malaise.
The drug helps reduce the severity of the following symptoms:
- hyperthermia( fever);
- feeling of heat and chills( feverish reaction);
- aches in the bones;
- muscle and headaches;
- nasal congestion;
- flow from the nose( rhinorrhea).
Please note: medication helps with allergic rhinitis and conjunctivitis.
When should Rince not be used?
Important: is an absolute contraindication to the commencement of taking this medication is an individual hypersensitivity to one or more active components or excipients.
Pathologies in which the drug is not prescribed:
- atherosclerosis of the heart arteries;
- "aspirin triad"( intolerance to salicylates and other NSAIDs in combination with bronchial asthma and polyposis of the nose or paranasal sinuses);
- severe functional kidney failure;
- hepatic insufficiency( incl. Against the background of alcoholism);
- hepatitis and other active liver diseases;
- erosive and ulcerative lesions of the digestive tract( in the phase of exacerbation);
- bleeding in the digestive tract;
Note: Rinsa is contraindicated in children and adolescents under 15 years of age.
Recommended doses of
Rinzu take inside 1 tablet during or after a meal.Multiplicity of taking the drug from pain and heat - 3-4 times a day( it is desirable to withstand 6-hour time intervals).The permissible daily dose is 4 tablets.It is not recommended to drink for more than 5 days in a row.
Side effects of
In the presence of allergies to the components of the drug, itching, rashes( "urticaria") and angioedema can occur.In severe cases, anaphylaxis is possible - the development of a life-threatening shock state.
In rare cases, the following side effects are noted:
- drowsiness during the day;
- is a psychomotor agitation;
- sensation of dry mouth;
- dyspepsia disorder;
- pain in the epigastric region( in the projection of the stomach);
- dilated pupil;
- violation of vision sharpness near;
- increased intraocular pressure;
- renal colic;
- interstitial nephritis;
- hepatic impairment;
- hepatonecrosis( necrosis of liver tissue);
- bronchial obstruction.
Mechanism of Action
Paracetamol inhibits the synthesis of cyclooxygenase and affects the hypothalamic centers of thermoregulation and pain, which is responsible for its analgesic and antipyretic properties.
Pheniafrin is α1-adrenomimetic.It has vasoconstrictor properties;Due to the narrowing of the vessels, the hyperemia and swelling of the nasal mucosa decreases.Thanks to this, nasal breathing is noticeably improved.
Chlorfenamine is a blocker of specific histamine receptors.By reducing the permeability of the vascular walls, it reduces inflammatory exudation and swelling.
Caffeine is a psychostimulator that helps to overcome general weakness and drowsiness.It somewhat strengthens the effect of the remaining components.
Against the backdrop of accidental excess of recommended single and( or) daily dosage, the symptoms, mainly caused by paracetamol poisoning, develop.The danger is the intake of 10 or more g of this substance.
Symptoms of overdose:
- abdominal pain;
- skin blushing;
- nausea and vomiting;
- worsening of blood clotting.
In case of paracetamol poisoning, the injured person should be called "ambulance", and before the doctors arrive, they should rinse the stomach and give enterosorbents( regular or white activated charcoal).
Within 8-9 hours, it is necessary to introduce a specific antidote - methionine, and after 12 hours, acetylcysteine is required to control the intoxication of .Overdose is the basis for hospitalization in the profile department of the hospital.In severe cases, the device is used to purify blood( hemosorption).
Interaction with other drugs
It is necessary to exclude simultaneous reception of Rinza with β-adrenoblockers, monoamine oxidase enzyme inhibitors and tricyclic antidepressants in association with a high risk of hepato- and nephrotoxic effects.
This preparation for colds potentiates the effect of sedatives( soothing).
Glucocorticosteroid hormones, when used concurrently, increase the likelihood of developing glaucoma.
Antiparkinsonics and antipsychotics increase the risk of diuresis and chronic constipation.
The active ingredient chlorphenamine in combination with furazolid can trigger a sharp jump in blood pressure and even hypertensive crisis.
Tricyclic antidepressants enhance the α-adrenomimetic effect of another ingredient - phenylephrine.
Special care must be taken in patients with the following diseases and pathological conditions:
- elevated blood pressure;
- bronchial asthma;
- closed angle glaucoma;
- blood diseases( including disorders of coagulability);
- ulcers and erosions of the gastrointestinal tract( without exacerbation, including in the anamnesis);
- prostate adenoma;
- pheochromocytoma( hormone-active tumor).
For the duration of treatment, it is necessary to refrain from taking alcoholic beverages and pharmacy alcoholic infusions, since ethanol enhances the hepatotoxic effect.
To avoid overdose, do not use other pharmacological agents that contain paracetamol.
For those who accept Rinzu, it is not recommended to drive vehicles and work with potentially dangerous mechanisms.There may be a decrease in the ability to concentrate.
Rinsa during pregnancy
During the period of gestation and breastfeeding of the baby, these tablets can not be taken from a cold. If it is necessary to carry out symptomatic therapy during lactation, you should consult a doctor.There may be a question about the temporary transfer of the child to artificial milk mixtures or about substituting the drug for a safer for the child's organism.
Storage and dispensing conditions from pharmacies
To purchase Rince tablets in a pharmacy, you will not need a doctor's prescription.
The drug should be kept in dark places with low humidity.Permissible storage temperature is not higher than + 25 ° С.
Shelf life is 3 years from the date of issue( marked on the package).
Keep out of the reach of children!
The analogues of Rinza are tableted preparations:
- COLD CONTACT FLUIP;
Plisov Vladimir, medical reviewer