Stugeron: to whom is Stugeron prescribed, indications for use, comparison with Cavinton

The drug is an excellent therapeutic and prophylactic agent, which has proven itself in vestibular disorders. The effect of the calcium channel blocker Stugeron is mainly based on the elimination of circulatory disorders in the brain.

Simply put, it is able to dilate the vessels of the brain and peripheral organs, improving blood circulation. It can be used to effectively treat ailments: numbness of the extremities, atherosclerosis, vestibular disorders.

Stugeron is produced as round flat tablets of the traditional white color for medicinal products. The medication is odorless and contains on one side the tablet at risk for breaking, and on the other, the name of the medication in English - "STUGERON".

The main active ingredient used in it is a biologically active substance called cinnarizine. One tablet contains 25 milligrams of cinnarizine and such auxiliary components: lactose, povidone, starch, silicic acid.

Subject to exact adherence to the dosage, if you take the medicine as prescribed by the attending physician, there are no dangerous effects on the body. Resorption of Stugeron occurs in the stomach and intestines. Achievement of the concentration of the drug Cmax in the blood plasma is observed in the interval from 1 to 3 hours from the moment of administration.

Plasma protein binding of cinnarizine occurs at 91 percent. Further, the complete metabolization of the drug by the liver begins. The half-life is four hours and occurs as metabolites.

The share of participation of body systems in cleansing from residual products of the drug is as follows:

• one third of the metabolites are excreted by the kidneys through the genitourinary system;
• two-thirds of the metalobids are excreted by the intestines.

The mechanism of action of the drug is a complex effect on the brain and ears, as well as the sympathetic nervous system. The complex of biologically active substances included in it has a vasodilating effect of brain tissues, at the same time practically does not affect the level of blood pressure. It allows you to selectively block the slow calcium channel, reduce the cellular intake of calcium ions, and optimize their concentration in the plasmolemma depot.

There is also an effect on the smooth muscles of the blood vessels, which is aimed at reducing their response to natural biologically active substances produced by the body - norepinephrine, adrenaline, dopamine, vasopressin, angiotensin.

In addition, Stugeron:

• increases the vasodilation of carbon dioxide;
• reduces the tone of smooth muscles of arterioles;
• increases muscle resistance to hypoxia;
• exhibits moderate antihistamine activity;
• lowers the tone of the sympathetic nervous system;
• reduces the excitability of the vestibular mechanism.

Additionally, the important pharmacological effect of the drug on erythrocytes should be noted. Taking Stugeron improves the elasticity of the membranes of red blood cells, increases their resistance to deformation, and reduces blood viscosity in general.

The drug Stugeron: indications for use, contraindications and side effects

The manufacturer of the medicinal product is Gedeon Rihter.

The pharmacy dispenses it in packs of tablets containing two blisters of 25 units.

The composition of each tablet includes 25 milligrams of cinnarizine and excipients used in pharmacology. The purpose of the excipients used in it is to improve the disintegration and absorption of the tablet after administration.

In addition, Stugeron is also available in capsules that contain 75 milligrams of cinnarizine, which is the equivalent of three tablets. Available in packs of 20 or 60 capsules.

It can be purchased as drops in pharmacological vials of 20 milliliters.

The content of the drug in one (1) milliliter is 75 milligrams, which corresponds to one capsule or three tablets.

The drug Stugeron has quite extensive indications for use. He is able to help with the treatment of a whole range of cerebrovascular accidents.

Prescribing a medication is often carried out in the case of a diagnosis related to diseases in one of four main categories:

1. Disruption of cerebral blood supply of various etiologiescaused by vascular spasm, the development of cerebral atherosclerosis, traumatic brain injury, discirculatory encephalopathy, ischemic stroke, genesis of the cerebral vessel. In this case, it acts as a supportive therapy.
2. Chronic cerebrovascular accident, which is complicated by the derivative range of inconveniences caused by this. These include irritability, headaches, migraines, memory impairments, fatigue, dizziness, tinnitus, senile dementia. Stugeron allows you to improve the patient's condition and reduce the discomfort caused by this circumstance.
3. Labyrinth disease of the inner ear and its symptoms. Its consequence is nausea, dizziness, nystagmus, vomiting.
4. Peripheral circulation disorders, which are accompanied by intermittent claudication (this disease is curable with Cilostazol), disorders of tissue trophism in diabetes, sensation of coldness in the extremities, night cramps of leg muscles, acrocyanosis, varicose and trophic ulcers, bedsores, obliterating atherosclerosis.

In addition, for the drug Stugeron, indications for use include Buerger's disease, Raynaud's and Parkinson's syndrome. It is often prescribed for the prevention of kinetosis in children and adults, better known as motion sickness. Also, this drug is often used not only as a therapeutic agent, but also a prophylactic drug for a whole range of discomfort conditions caused by a violation of the normal blood supply brain.

For the drug Stugeron, indications for use include a fairly extensive list of cases, due to its safety. But, being a drug, it has some contraindications, which is considered the norm for any drug. Contraindications are mainly based on the lack of data on the effect of the components of the drug on a woman's pregnancy and her future fetus. Its reception is justified only by an urgent need, since there is a potential risk for the unborn child.

Similarly, the drug Stugeron, the indications for the use of which make it possible to recommend it as a treatment for numerous disorders of blood supply to the brain and peripheral nervous system - has not been studied for the effect of cinnarizine during the period lactation. The reasons for this, as in the first case, are clear - in addition to the moral and ethical standards of such research, no sane mother would risk the health of her future or newborn baby. Therefore, in case of an urgent need to take the drug, lactation is recommended to stop.

It is recommended to refuse taking the medicine for people who have an individual intolerance to any of the components that make up the drug.

It is noted that the reception cinnarizine does not have any side effects if the correct dosage and recommendations of the attending physician are followed.

In some cases, there are such uncomfortable conditions as:

• upset gastrointestinal tract;
• allergic reactions;
• drowsiness;
• feeling of dry mouth;
• sweating;
• headache and others.

Many of them are eliminated by simply changing the dose of the drug. However, when side effects appear, taking it at an advanced age should be adjusted and continued only with the permission of a doctor.

The maximum permissible daily dose should not exceed 225 mg or 9 tab. There is no specific antidote. Drug overdose is eliminated by the classical method of detoxification of the body, consisting of gastric lavage and intake of activated charcoal. If necessary, symptomatic therapy is carried out.

Stugeron tablets: instructions for use, interaction with other drugs

The instructions for use allow taking the medicine before meals, but then the patient must prepare for the consequences of possible irritation of the gastric mucosa. Basically, Stugeron tablets produced by Gedeon Richter are taken orally after meals. It is recommended to bite the Stugeron tablet, write down with at least one glass of still water.

Side effects in a person taking the drug indicate a possible allergy. Most likely, the patient has a hypersensitivity to one or more of the ingredients in the drug, such as lactose or magnesium stearate. In addition, each Stugeron tablet contains silicon, magnesium, and talc, which, although they are hypoallergenic, are still capable of enhancing the action of other biologically active elements.

Depending on the severity and intensity of side effects, the attending physician will be able to determine the optimal dose of the drug in order to provide an auxiliary effect. Usually, to ensure the "habituation" of the body to cinnarizine, the description of the drug suggests prescribing half the standard recommended dose. In this mode, the drug is taken for one to three weeks. After that, they usually move on to the selected dosage.

The standard dosage of the drug depends on the diagnosis. An adult and children from 12 years old can take:

• from 25 to 50 milligrams three times a day for circulatory disorders of the brain, for the prevention of migraine;
• three times a day from 50 to 75 mg. in the treatment of disorders of peripheral blood supply;
• one tablet or 25 milligrams three times a day for the treatment of vestibular disorders;
• prevention of kinetosis requires taking 1 tablet 30 minutes before the start of the trip and 25 milligrams every 6 hours after its completion, as needed.

For children under twelve, half of the "adult" dose of the drug is prescribed, which is relevant for a particular disease. Reception is also carried out three times a day. Remember that only Stugeron tablets are suitable for children, and drops or capsules are indicated only after the age of twelve. Dr. Komarovsky has already proved once that a healthy baby does not need him.

The use of the drug, regardless of its pharmacological form, is absolutely contraindicated during pregnancy (it is said above that it has simply not been studied). A newborn should also not receive it during breastfeeding. The effect of the drug on the formation of an unborn child's body or its development when cinnarizine enters the mother's breast milk has not been studied. In these situations, medicine strictly recommends refraining from taking it until its benefits or harms have been proven.

Interaction of the drug with other drugs and alcohol can increase the sedative effects of either the drug or mixed drugs.

An increase in the sedative effect is observed with the simultaneous administration of cinnarizine and:

• alcohol;
• tricyclic antidepressants - Desipramine and similar;
• hypnotics - Zaleplona, ​​Melatonin, Zopiclone, others;
• sedatives - Corvalol, Validol and others.

Mutual enhancement of therapeutic effects is observed while taking the drug Stugeron:

• antihypertensive drugs - Adelfana, Metoprolol, Anaprilina, Captopril, Losartan, their analogues;
• drugs of the nootropic group - Biotredin, Idebenone, Cerebrolysin, Meclofenoxate, Cortexin and others;
• vasodilators - Actovegin, Trental, Vinpocetine, Euphyllin, and other drugs belonging to this group.

The simultaneous reception of Stugeron and hypertensive drugs reduces the severity of their action. That is, the effect of increasing blood pressure with Caffeine, Cordinamine, Mezaton and others in this case will be minimal. The effectiveness of Stugeron is minimized by exposure to Phenylpropanolamine.

Stugeron or Cavinton, which is better: comparison, drug analogues and reviews

Analogous drugs, which are Cavinton and Stugeron, have a similar effect on cerebral blood flow.

Therefore, the question of Stugeron or Cavinton is that it is better to be asked quite often by a person who is unfamiliar with the peculiarities of the effect on the body of each of them. Providing a similar effect on the problem of cerebral circulation, each of the drugs does it in its own way.

Therefore, it is impossible to argue that one is better than the other - it depends on the characteristics of the organism. It all depends on which of them the neurologist recommends to a particular patient.

At the same time, choosing from Stugeron or Cavinton, which is better to use, it can be difficult to find out. Any of them can become not only a cure for an ailment, but also a source of problems at the same time. For example, Cavinton has more than one positive review. Its reception is accompanied by clarity in the head, the speed of mental reactions increases.

But along with this comes the feeling of "work to wear" during the usual rhythm of life. Cavinton is capable of causing deterioration in concentration, reduces the effectiveness of a person during monotonous work and is not suitable for cases where perseverance or prolonged stress is required attention.

Stugeron also offers a clear head effect, but instead of boosting the nervous system, it calms it down. Therefore, its reception is recommended not only for the treatment of problems with cerebral circulation, but also for those who are faced with a monotonous educational process, an occupation that requires perseverance, high concentration. The choice of "calm" Stugeron or Cavinton, which is better suited for active, but not monotonous work - it must be done with the above in mind.

Cinnarizine is a drug complex that is often presented as an analogue of Stugeron due to the same main active substance in the tablet. But all the same, there are differences between them, mainly qualitative. For the production of Stugeron, a higher degree of purification of cinnarizine is carried out than for the drug, the name of which corresponds to the main component of the tablet.

The degree of purification is an important condition for the effectiveness of any medical product and is calculated by simple formula - the cleaner, the more effective any biologically active ingredient in the drug substance. Also, the high purity of cinnarizine means a decrease in the likelihood of developing side effects caused by impurities. In the bare residue, when comparing Stugeron and Cinnarizin, we can say that their main difference between themselves is only the degree of purification of the main biologically active component.

Analogues of the drug Stugeron are divided into two main groups - analogs and synonyms. Each group is a complex of drugs that have a similar therapeutic effect, but have their own unique pharmacological characteristics.

Similar drugs are a structural analogue of the "parent" drug with the same main active ingredient in the composition. For Stugeron, "similar" are: the already mentioned Cinnarizin, as well as Vertizin, Cinnasan, Tsinedil, Cinnaron.

Also, to prevent the development or cure atherosclerosis will help Alirokumab, and with Parkinson's disease will help Selegiline.

An analogue is a group of medicines that contains another active substance or a combination of those, but has a similar therapeutic effect on the body.

For Stugeron, there are many analogs that are produced in tablets or in another form. The most famous of them are:

1. Tablets: Asniton, Betagistin, Betahistin-C3, Betaver, Betacetrin, Betaserc, Vestibo, Deinos, Mexidol and Microzer in the form of tablets, Neuroxymet, Tagista, Tanakan, Enerion.
2. Oral solution: Microserine in the form of drops, Memorin, Tanakan in a soluble form for oral administration.
3. Oral capsules: Cerebrovital.
4. Solution for injection: liquid form of Mexidol, Neurotropin.

The cost of one package of Stugeron (50 tablets) varies depending on the region of Russia. Usually it is within 140-250 rubles. Stugeron is a prescription drug. The price for the pharmacological option in the form of capsules or solution for injection changes in the same way.